Results 41 to 50 of about 4,808 (171)

Identification of Potential Drug Targets for Antiplatelet Therapy Specifically Targeting Platelets of Old Individuals through Proteomic Analysis

open access: yesBiomedicines, 2023
Aging is a growing problem worldwide, and the prevalence and mortality of arterial and venous thromboembolism (VTE) are higher in the elderly than in the young population. To address this issue, various anticoagulants have been used. However, no evidence
Seung Hee Lee   +6 more
doaj   +1 more source

Orosomucoid Content of Pleural and Peritoneal Effusions [PDF]

open access: yesJournal of Clinical Investigation, 1974
22 nonneoplastic, noninflammatory effusions (cirrhosis and congestive heart failure), 12 non-neoplastic inflammatory effusions (tuberculosis, lupus erythematosus, rheumatoid arthritis, and idiopathic pleuropericarditis), and 58 neoplastic effusions (cancer of lung, breast, ovary, and pancreas, and lymphoma) were analyzed by radial immunodiffusion for ...
D, Rudman   +5 more
openaire   +2 more sources

Salivary orosomucoid 1 as a biomarker of hepatitis B associated hepatocellular carcinoma

open access: yesScientific Reports, 2022
Saliva is rich in proteins, DNA, RNA and microorganisms, and can be regarded as a biomarker library. In order to explore a noninvasive and simple means of early screening for liver cancer, proteomics was used to screen salivary markers of hepatitis B ...
Jiaoxia He   +5 more
doaj   +1 more source

Orosomucoid: a promising biomarker for the assessment of exercise-induced fatigue triggered by basic combat training

open access: yesBMC Sports Science, Medicine and Rehabilitation, 2022
Background Orosomucoid (ORM) is a positive acute phase protein verified to be upregulated in various forms of exercise-induced fatigued (EIF) rodents. However, its association with EIF among human beings remained unknown.
Yi Ruan   +7 more
doaj   +1 more source

Orosomucoid, Carotid Plaque, and Incidence of Stroke [PDF]

open access: yesStroke, 2016
Background and Purpose— Orosomucoid (α-1-acid glycoprotein) is an acute-phase protein that has been implicated in anti-inflammatory, immunomodulating, and angiogenic pathways. Orosomucoid has also been associated with coronary disease and stroke.
John, Berntsson   +5 more
openaire   +2 more sources

Spectroscopic and Theoretical Analysis of the Interaction between Plasma Proteins and Phthalimide Analogs with Potential Medical Application

open access: yesLife, 2023
One of the groups of organic compounds with potential use in medicine and pharmacy is phthalimide derivatives. They are characterized by a wide range of properties such as antibacterial, antifungal, and anti-inflammatory.
Edward Krzyżak   +3 more
doaj   +1 more source

Association of the serological status of rheumatoid arthritis patients with two circulating protein biomarkers: A useful tool for precision medicine strategies

open access: yesFrontiers in Medicine, 2022
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints and presence of systemic autoantibodies, with a great clinical and molecular heterogeneity.
Cristina Ruiz-Romero   +13 more
doaj   +1 more source

Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients

open access: yesBMC Pharmacology and Toxicology, 2018
Background Recent studies indicate that inflammation may also affect CYP3A4 activity. Associations of CYP3A4-mediated metabolism of quinine, with inflammatory biomarkers were investigated in patients undergoing maintenance hemodialysis (HD).
Hadi Molanaei   +7 more
doaj   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin   +11 more
wiley   +1 more source

Retinal vascular caliber is associated with cardiovascular biomarkers of oxidative stress and inflammation: the POLA study.

open access: yesPLoS ONE, 2013
PurposeRetinal vascular caliber has been linked with increased cardiovascular risk and is predictive of cardiovascular pathology, including stroke and coronary heart disease. Oxidative stress, as well as inflammatory mechanisms, plays a major role in the
Vincent Daien   +7 more
doaj   +1 more source

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