Results 81 to 90 of about 4,733 (152)

Therapeutic Target Discovery for Multiple Myeloma: Identifying Druggable Genes via Mendelian Randomization

Biomedicines
Background: Multiple myeloma (MM) is a hematological malignancy originating from the plasma cells present in the bone marrow. Despite significant therapeutic advancements, relapse and drug resistance remain major clinical challenges, highlighting the ...
Shijun Jiang, Fengjuan Fan, Qun Li, Liping Zuo, Aoshuang Xu, Chunyan Sun   +5 more
doaj   +1 more source

Corrigendum to "Orosomucoid 1 Attenuates Doxorubicin-Induced Oxidative Stress and Apoptosis in Cardiomyocytes via Nrf2 Signaling". [PDF]

Biomed Res Int, 2022
Cheng X, Liu D, Xing R, Song H, Tian X, Yan C, Han Y.   +6 more
europepmc   +1 more source

Comparison of orosomucoid-1 immunoexpression and angiogenesis between oral squamous cell carcinoma cases with different histological grades. [PDF]

J Oral Maxillofac Pathol, 2021
Sánchez-Romero C, Bologna-Molina R, González-González R, Salazar-Rodríguez S, Mendoza NB.   +4 more
europepmc   +1 more source

Pudilan Anti-inflammatory Oral Liquid and Organic Acid Component from Taraxaci Herba Attenuate Allergic Asthma in Young Mice Through Toll-like Receptor 2/Toll-like Receptor 4 Signaling Pathway

World Journal of Traditional Chinese Medicine
Objective: Allergic asthma (AA) is a chronic airway inflammatory disease characterized by airway hyper-responsiveness (AHR). Pudilan anti-inflammatory oral liquid (PDL), along with its main medicinal material, Taraxaci Herba (Taraxacum mongolicum Hand ...
Yu-Zhi Mao, Chen-Zi Li, Wei-Quan Bu, Bing Yang, Ya-Ping Chen, Jun Liu, Jing Zhao, E Sun, Xiao-Bin Jia, Liang Feng   +9 more
doaj   +1 more source

Independent association of a 17q21 variant with exacerbations in type 2–low adult asthma

Journal of Allergy and Clinical Immunology: Global
Background: The genetic factors contributing to exacerbations in type 2–low asthma are not well understood. Objective: We sought to clarify the association between variants in gasdermin B/orosomucoid-like 3 (GSDMB/ORMDL3) on 17q21 and exacerbations in ...
Yumi Ishiyama, MD, Hisako Matsumoto, MD, PhD, Hironobu Sunadome, MD, PhD, Yuji Tohda, MD, PhD, Takahiko Horiguchi, MD, PhD, Hideo Kita, MD, PhD, Kazunobu Kuwabara, MD, PhD, Keisuke Tomii, MD, PhD, Kojiro Otsuka, MD, PhD, Masaki Fujimura, MD, PhD, Noriyuki Ohkura, MD, PhD, Katsuyuki Tomita, MD, PhD, Akihito Yokoyama, MD, PhD, Hiroshi Ohnishi, MD, PhD, Yasutaka Nakano, MD, PhD, Tetsuya Oguma, MD, PhD, Soichiro Hozawa, MD, PhD, Yoshihiro Kanemitsu, MD, PhD, Tadao Nagasaki, MD, PhD, Isao Ito, MD, PhD, Tsuyoshi Oguma, MD, PhD, Hideki Inoue, MD, PhD, Tomoko Tajiri, MD, PhD, Toshiyuki Iwata, MD, PhD, Junya Ono, BS, Shoichiro Ohta, MD, PhD, Tomomitsu Hirota, DOS, PhD, Mayumi Tamari, MD, PhD, Akio Niimi, MD, PhD, Kenji Izuhara, MD, PhD, Michiaki Mishima, MD, PhD, Toyohiro Hirai, MD, PhD   +31 more
doaj   +1 more source

Transcriptional response to combination antiretroviral therapy predicts side effects and novel targets

Frontiers in Pharmacology
BackgroundAntiretroviral therapy (ART) has revolutionized the clinical management of people with human immunodeficiency virus (HIV), transforming HIV infection into a chronic condition.
Alexander Lachmann, Alexander Lachmann, Alexander Lachmann, Letizia Amadori, Letizia Amadori, Paola Nicoletti, Heidi M. Crane, Chiara Giannarelli, Avi Ma’ayan, Avi Ma’ayan, Avi Ma’ayan, Inga Peter   +11 more
doaj   +1 more source

Corrigendum: Orosomucoid 1 is involved in the development of chronic allograft rejection after kidney transplantation [PDF]

International Immunology, 2020
Haruka, Higuchi, Daisuke, Kamimura, Jing-Jing, Jiang, Toru, Atsumi, Daiki, Iwami, Kiyohiko, Hotta, Hiroshi, Harada, Yusuke, Takada, Hiromi, Kanno-Okada, Kanako C, Hatanaka, Yuki, Tanaka, Nobuo, Shinohara, Masaaki, Murakami   +12 more
openaire   +2 more sources

Fatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle Endurance. [PDF]

Sci Rep, 2016
Lei H, Sun Y, Luo Z, Yourek G, Gui H, Yang Y, Su DF, Liu X.   +7 more
europepmc   +1 more source

Functional Molecular Plasma Biomarkers of Inflammation and Repair in Kidney Disease Progression in Gum Arabica Modality of CKD. [PDF]

Int J Mol Sci
AlShelleh S, Suyagh M, Alhawari H, Bulatova N, Kasabri V, Wahbeh A, Alawwa I, Oweis A, Mustafa H.   +8 more
europepmc   +1 more source

Association of the rs7216389 Polymorphism in Orosomucoid-Like 3 (ORMDL3) Gene With Childhood Asthma: A Multicenter Case-Control Study. [PDF]

Cureus
Khan QU, Nasir M, Asif AB, Khan JA, Eman K, Farid M.   +5 more
europepmc   +1 more source