Results 51 to 60 of about 4,091 (157)
Microbial Biotechnology, Volume 17, Issue 5, May 2024.The study investigates the symbiotic interaction between Veillonella dispar and three lactic acid bacteria strains, revealing a robust mutualism primarily with Lactobacillus acidophilus. Through co‐culture experiments and transcriptomic analysis, the research elucidates a complex metabolic relationship involving cross‐feeding of lactate and glutamate ...
Shi‐Min Zhang +3 more
wiley +1 more source
ELISA: Structure-Function Inferences Based On Statistically Significant and Evolutionarily Inspired Observations [PDF]
, 2010 The problem of functional annotation based on homology modeling is primary to current bioinformatics research. Researchers have noted regularities in sequence, structure and even chromosome organization that allow valid functional cross-annotation ...
Comeau, Steve +5 more
core +1 more source
EFSA Journal, Volume 22, Issue 3, March 2024.Abstract Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 6‐phytase produced by the genetically modified strain Aspergillus oryzae DSM 33737 (HiPhorius™ 10, 40, 20L and 50L) as a zootechnical feed ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +26 more
wiley +1 more source
Microbial Biotechnology, Volume 17, Issue 2, February 2024.Here we consolidate knowledge on chemical agents that affect DNA repair meechanisms and how they have been employed to enhance sucess in mammalian cells and some yeast. Abstract The ability to precisely edit genomes by deleting or adding genetic information enables the study of biological functions and the building of efficient cell factories.
Min Lu, Sonja Billerbeck
wiley +1 more source
A new target for differentiation therapy in AML [PDF]
, 2016 Despite major advances in understanding the genetics and epigenetics of acute myelogenous leukemia, there is still a great need to develop more specific and effective therapies.
Hess, Jay L, Ma, Peilin, Song, Weihua
core +1 more source
BioMed Research International, Volume 2024, Issue 1, 2024.Background. Aliarcobacter butzleri is a Gram‐negative, curved or spiral‐shaped, microaerophilic bacterium and causes human infections, specifically diarrhea, fever, and sepsis. The research objective of this study was to employ computer‐aided drug design techniques to identify potential natural product inhibitors of a vital enzyme in this bacterium ...
Zarrin Basharat +5 more
wiley +1 more source
EFSA Journal, Volume 22, Issue 1, January 2024.Abstract The food enzyme phosphoinositide phospholipase C (1‐phosphatidyl‐1D‐myo‐inositol‐4,5‐bisphosphate inositoltrisphosphohydrolase EC 3.1.4.11.) is produced with the genetically modified Pseudomonas fluorescens strain PIC by DSM Food specialties B.V. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable
EFSA Panel on Food Contact Materials +22 more
wiley +1 more source
Transcriptional alterations under continuous or pulsatile dopaminergic treatment in dyskinetic rats [PDF]
, 2018 Continuous dopaminergic treatment is considered to prevent or delay the occurrence of dyskinesia in patients with Parkinson's disease (PD). Rotigotine is a non-ergolinic D3>D2>D1 dopamine-receptor agonist for the treatment of PD using a transdermal ...
Gerlach, M. +4 more
core
The antilymphocytic activity of brequinar sodium and its potentiation by cytidine: Effects on lymphocyte proliferation and cytokine production [PDF]
, 1993 Based on its capacity to inhibit de novo pyrimidine biosynthesis by blocking dihydroorotate dehydrogenase activity, the antitumor agent brequinar sodium (BQR) has emerged as a new immunosuppressive agent.
Lemster, B +4 more
core +1 more source
Characterization of Treponema denticola pyrF encoding orotidine-5′-monophosphate decarboxylase [PDF]
, 2007 The Treponema denticola ATCC 35405 genome annotation contains most of the genes for de novo pyrimidine biosynthesis. To initiate characterization of pyrimidine synthesis in Treponema , we focused on TDE2110 (the putative pyrF , encoding orotidine-5 ...
Bach +37 more
core +1 more source