Serological Evidence of Human Orthohantavirus Infections in Barbados, 2008 to 2016 [PDF]
Pathogens, 2021 Background: Hantavirus pulmonary syndrome (HPS) is well-known in South and North America; however, not enough data exist for the Caribbean. The first report of clinical orthohantavirus infection was obtained in Barbados, but no other evidence of clinical
Kirk Osmond Douglas +5 more
doaj +12 more sources
First Evidence of Akodon-Borne Orthohantavirus in Northeastern Argentina [PDF]
EcoHealth, 2021 Orthohantaviruses (genus Orthohantavirus, family Hantaviridae) are the etiologic agents of Hantavirus Pulmonary Syndrome in the Americas. In South America, orthohantaviruses are highly diverse and are hosted by sigmodontine rodents (subfamiliy ...
Bellomo, Carla María +5 more
core +6 more sources
Orthohantavirus Replication in the Context of Innate Immunity [PDF]
Viruses, 2023 Orthohantaviruses are rodent-borne, negative-sense RNA viruses that are capable of causing severe vascular disease in humans. Over the course of viral evolution, these viruses have tailored their replication cycles in such a way as to avoid and/or ...
Autumn LaPointe +2 more
doaj +4 more sources
Characterisation of Orthohantavirus Serotypes in Human Infections in Kazakhstan [PDF]
VirusesOrthohantavirus infection is a zoonotic disease transmitted to humans through contact with infected rodents. In Eurasia, Old World Orthohantaviruses can cause haemorrhagic fever with renal syndrome (HFRS), while in the Americas, New World ...
Nur Tukhanova +10 more
doaj +3 more sources
Prevalence of Orthohantavirus-Reactive Antibodies in Humans and Peri-Domestic Rodents in Northern Ethiopia [PDF]
Viruses, 2021 In 2012, Tigray orthohantavirus was discovered in Ethiopia, but its seasonal infection in small mammals, and whether it poses a risk to humans was unknown.
Yonas Meheretu +12 more
doaj +2 more sources
Serological Evidence of Multiple Zoonotic Viral Infections among Wild Rodents in Barbados [PDF]
Pathogens, 2021 Background: Rodents are reservoirs for several zoonotic pathogens that can cause human infectious diseases, including orthohantaviruses, mammarenaviruses and orthopoxviruses.
Kirk Osmond Douglas +6 more
doaj +6 more sources
Evidence of orthohantavirus and leptospira infections in small mammals in an endemic area of Gampaha district in Sri Lanka [PDF]
One Health Outlook, 2022 Background Orthohantaviruses and leptospira are emerging zoonotic pathogens of high public health significance. The epidemiology of orthohantavirus infections and leptospirosis is similar and presents related clinical pictures in humans.
N. P. Sunil-Chandra +6 more
doaj +2 more sources
Increased Heparanase Levels in Urine during Acute Puumala Orthohantavirus Infection Are Associated with Disease Severity [PDF]
Viruses, 2022 Old–world orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS), characterized by acute kidney injury (AKI) with transient proteinuria. It seems plausible that proteinuria during acute HFRS is mediated by the disruption of the glomerular ...
Luz E. Cabrera +8 more
doaj +9 more sources
Discovery and characterization of Sager Creek virus, a new orthohantavirus in prairie voles (Microtus ochrogaster) [PDF]
npj VirusesWe report the discovery and characterization of a new orthohantavirus species in prairie voles (Microtus ochrogaster) named Sager Creek virus (SACRV).
Nathaniel Mull +6 more
doaj +2 more sources
A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies. [PDF]
PLoS PathogensOrthohantaviruses are emerging zoonotic viruses that can infect humans via the respiratory tract. There is an unmet need for an in vivo model to study infection of different orthohantaviruses in physiologically relevant tissue and to assess the efficacy ...
Melanie Rissmann +12 more
doaj +2 more sources