Results 1 to 10 of about 8,842 (202)

Serological Evidence of Human Orthohantavirus Infections in Barbados, 2008 to 2016 [PDF]

Pathogens, 2021
Background: Hantavirus pulmonary syndrome (HPS) is well-known in South and North America; however, not enough data exist for the Caribbean. The first report of clinical orthohantavirus infection was obtained in Barbados, but no other evidence of clinical
Kirk Osmond Douglas, Thelma Alafia Samuels, Rommel Iheozor-Ejiofor, Olli Vapalahti, Tarja Sironen, Marquita Gittens-St. Hilaire   +5 more
doaj   +8 more sources

A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies. [PDF]

PLoS Pathogens
Orthohantaviruses are emerging zoonotic viruses that can infect humans via the respiratory tract. There is an unmet need for an in vivo model to study infection of different orthohantaviruses in physiologically relevant tissue and to assess the efficacy ...
Melanie Rissmann, Danny Noack, Thomas M Spliethof, Vincent P Vaes, Rianne Stam, Peter van Run, Jordan J Clark, Georges M G M Verjans, Bart L Haagmans, Florian Krammer, Marion P G Koopmans, Judith M A van den Brand, Barry Rockx   +12 more
doaj   +3 more sources

First Molecular Detection of Orthohantaviruses (Orthohantavirus hantanense and O. jejuense) in Trombiculid Mites from Wild Rodents in the Republic of Korea [PDF]

Pathogens
Orthohantaviruses are zoonotic pathogens that cause severe diseases in humans primarily through inhalation of aerosols from rodent excreta. Recent studies suggest that ectoparasites may be potential vectors for Orthohantaviruses.
Seong Yoon Kim, Hak Seon Lee, Hyunyoung Yoon, Hee Il Lee   +3 more
doaj   +3 more sources

Orthohantavirus seoulense as a cause of acute, dengue-negative febrile illness in southern Vietnam. [PDF]

Trans R Soc Trop Med Hyg
Background Dengue fever has surged in Vietnam since 2021; however, the aetiology of non-dengue undifferentiated febrile illnesses remains poorly understood.
Quynh Le MT, Yoshimatsu K, Abe H, Nguyen TT, Khanh Nguyen HL, Ung TTH, Hoang PVM, Koizumi N, Hasebe F, Miura K.   +9 more
europepmc   +3 more sources

Discovery and characterization of Sager Creek virus, a new orthohantavirus in prairie voles (Microtus ochrogaster) [PDF]

npj Viruses
We report the discovery and characterization of a new orthohantavirus species in prairie voles (Microtus ochrogaster) named Sager Creek virus (SACRV).
Nathaniel Mull, Mert Erdin, Michael Letko, Stephanie N. Seifert, Tarja Sironen, Teemu Smura, Kristian M. Forbes   +6 more
doaj   +3 more sources

Characterisation of Orthohantavirus Serotypes in Human Infections in Kazakhstan [PDF]

Viruses
Orthohantavirus infection is a zoonotic disease transmitted to humans through contact with infected rodents. In Eurasia, Old World Orthohantaviruses can cause haemorrhagic fever with renal syndrome (HFRS), while in the Americas, New World ...
Nur Tukhanova, Anna Shin, Abhishek Bakuli, Lyazzat Yeraliyeva, Nurbek Maikanov, Guenter Froeschl, Zauresh Zhumadilova, Gulnara Tokmurziyeva, Edith Wagner, Sandra Essbauer, Lukas Peintner   +10 more
doaj   +3 more sources

Novel Orthohantavirus Associated with Hantavirus Pulmonary Syndrome in Northern Argentina [PDF]

Viruses
In this work, we performed the genetic characterization of a new variant of orthohantavirus associated with a fatal case of hantavirus pulmonary syndrome, outside the known endemic region, in northwestern Argentina.
Carla M. Bellomo, Sebastian Kehl, Daniel Oscar Alonso, Walter López, Flavia Cassinelli, Rocío María Coelho, Gabriela Bravo, Sara Aguirre, Marcela Dib, Natalia Periolo, Concepción Toscano, José Gil, Francisco García Campos, Ignacio Ferro, Valeria Paula Martinez   +14 more
doaj   +3 more sources

Lanka virus, a Mus booduga-borne orthohantavirus infection-associated febrile illness in Sri Lanka. [PDF]

PLoS Negl Trop Dis
Background In Sri Lanka, a high seroprevalence of antibodies against hantaviruses was reported in communities affected by chronic kidney disease of unknown etiology (CKDu).
Muthusinghe DS, Senarathne P, Shimizu K, Sarathkumara YD, Nanayakkara S, Lokupathirage SMW, Wei Z, Rathnayake NS, Vijeyakumaran R, Koizumi N, Kawakami T, Koizumi A, Harada KH, Dissanayake N, Kularathne SAM, Tsuda Y, Urata S, Arikawa J, Gamage CD, Yoshimatsu K.   +19 more
europepmc   +3 more sources

Use of a diagnostic Puumala virus real-time RT-PCR in an orthohantavirus endemic region in the Netherlands [PDF]

Microbiology Spectrum
Laboratory diagnosis of orthohantavirus infection is primarily based on serology. However, for a confirmed serological diagnosis, evaluation of a follow-up serum sample is essential, which is time consuming and causes delay.
Felix Geeraedts, Mariska Wevers, Froukje Bosma, Maria de Boer, J. N. Brinkman, Corine Delsing, Corine GeurtsvanKessel, Barry Rockx, Adri van der Zanden, Gozewijn D. Laverman   +9 more
doaj   +3 more sources

Prevalence of Orthohantavirus-Reactive Antibodies in Humans and Peri-Domestic Rodents in Northern Ethiopia [PDF]

Viruses, 2021
In 2012, Tigray orthohantavirus was discovered in Ethiopia, but its seasonal infection in small mammals, and whether it poses a risk to humans was unknown.
Yonas Meheretu, Åsa Granberg, Gebregiorgis Berhane, Hussein Khalil, Olivia Wesula Lwande, Mengistu Mitiku, Kiros Welegerima, Joëlle Goüy de Bellocq, Josef Bryja, Hagos Abreha, Herwig Leirs, Frauke Ecke, Magnus Evander   +12 more
doaj   +2 more sources