Results 1 to 10 of about 7,244 (150)

Characterisation of Orthohantavirus Serotypes in Human Infections in Kazakhstan [PDF]

Viruses
Orthohantavirus infection is a zoonotic disease transmitted to humans through contact with infected rodents. In Eurasia, Old World Orthohantaviruses can cause haemorrhagic fever with renal syndrome (HFRS), while in the Americas, New World ...
Nur Tukhanova, Anna Shin, Abhishek Bakuli, Lyazzat Yeraliyeva, Nurbek Maikanov, Guenter Froeschl, Zauresh Zhumadilova, Gulnara Tokmurziyeva, Edith Wagner, Sandra Essbauer, Lukas Peintner   +10 more
doaj   +3 more sources

First Molecular Detection of Orthohantaviruses (Orthohantavirus hantanense and O. jejuense) in Trombiculid Mites from Wild Rodents in the Republic of Korea [PDF]

Pathogens
Orthohantaviruses are zoonotic pathogens that cause severe diseases in humans primarily through inhalation of aerosols from rodent excreta. Recent studies suggest that ectoparasites may be potential vectors for Orthohantaviruses.
Seong Yoon Kim, Hak Seon Lee, Hyunyoung Yoon, Hee Il Lee   +3 more
doaj   +2 more sources

Discovery and characterization of Sager Creek virus, a new orthohantavirus in prairie voles (Microtus ochrogaster) [PDF]

npj Viruses
We report the discovery and characterization of a new orthohantavirus species in prairie voles (Microtus ochrogaster) named Sager Creek virus (SACRV).
Nathaniel Mull, Mert Erdin, Michael Letko, Stephanie N. Seifert, Tarja Sironen, Teemu Smura, Kristian M. Forbes   +6 more
doaj   +2 more sources

A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies. [PDF]

PLoS Pathogens
Orthohantaviruses are emerging zoonotic viruses that can infect humans via the respiratory tract. There is an unmet need for an in vivo model to study infection of different orthohantaviruses in physiologically relevant tissue and to assess the efficacy ...
Melanie Rissmann, Danny Noack, Thomas M Spliethof, Vincent P Vaes, Rianne Stam, Peter van Run, Jordan J Clark, Georges M G M Verjans, Bart L Haagmans, Florian Krammer, Marion P G Koopmans, Judith M A van den Brand, Barry Rockx   +12 more
doaj   +2 more sources

Pathogenicity and virulence of Rodent-Borne Orthohantaviruses [PDF]

Virulence
The Orthohantavirus genus in the family Hantaviridae includes viruses that cause zoonotic diseases in humans known as hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Exposure of humans to these viruses occurs through
Shannon L. Taylor, Connie S. Schmaljohn, Evan P. Williams, Colleen B. Jonsson   +3 more
doaj   +2 more sources

Interactions Between Hantavirus Nucleoprotein and Glycoproteins: A Quantitative Fluorescence Microscopy Study [PDF]

Viruses
Orthohantaviruses are tri-segmented negative-sense RNA viruses that can cause severe pathologies in humans. Currently, limited information exists on the molecular interactions driving orthohantavirus assembly in infected cells.
Amit Koikkarah Aji, Titas Mandal, Salvatore Chiantia   +2 more
doaj   +2 more sources

Novel Orthohantavirus Associated with Hantavirus Pulmonary Syndrome in Northern Argentina [PDF]

Viruses
In this work, we performed the genetic characterization of a new variant of orthohantavirus associated with a fatal case of hantavirus pulmonary syndrome, outside the known endemic region, in northwestern Argentina.
Carla M. Bellomo, Sebastian Kehl, Daniel Oscar Alonso, Walter López, Flavia Cassinelli, Rocío María Coelho, Gabriela Bravo, Sara Aguirre, Marcela Dib, Natalia Periolo, Concepción Toscano, José Gil, Francisco García Campos, Ignacio Ferro, Valeria Paula Martinez   +14 more
doaj   +2 more sources

Serological Evidence of Human Orthohantavirus Infections in Barbados, 2008 to 2016

Pathogens, 2021
Background: Hantavirus pulmonary syndrome (HPS) is well-known in South and North America; however, not enough data exist for the Caribbean. The first report of clinical orthohantavirus infection was obtained in Barbados, but no other evidence of clinical
Kirk Osmond Douglas, Thelma Alafia Samuels, Rommel Iheozor-Ejiofor, Olli Vapalahti, Tarja Sironen, Marquita Gittens-St. Hilaire   +5 more
doaj   +1 more source

Clinical and Molecular Epidemiology of Hemorrhagic Fever with Renal Syndrome Caused by Orthohantaviruses in Xiangyun County, Dali Prefecture, Yunnan Province, China

Vaccines, 2023
Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease transmitted by several rodent species. We obtained clinical data of HFRS patients from the medical records of the People’s Hospital of Xiangyun County in Dali Prefecture from July 2019 to
Hao Huang, Meng Fu, Peiyu Han, Hongmin Yin, Zi Yang, Yichen Kong, Bo Wang, Xinglou Yang, Tilian Ren, Yunzhi Zhang   +9 more
doaj   +1 more source

Prevalence of Orthohantavirus-Reactive Antibodies in Humans and Peri-Domestic Rodents in Northern Ethiopia

Viruses, 2021
In 2012, Tigray orthohantavirus was discovered in Ethiopia, but its seasonal infection in small mammals, and whether it poses a risk to humans was unknown.
Yonas Meheretu, Åsa Granberg, Gebregiorgis Berhane, Hussein Khalil, Olivia Wesula Lwande, Mengistu Mitiku, Kiros Welegerima, Joëlle Goüy de Bellocq, Josef Bryja, Hagos Abreha, Herwig Leirs, Frauke Ecke, Magnus Evander   +12 more
doaj   +1 more source