Results 11 to 20 of about 7,244 (150)
The Immune Correlates of Orthohantavirus Vaccine [PDF]
Vaccines, 2021 Zoonotic transmission of orthohantaviruses from rodent reservoirs to humans has been the cause of severe fatalities. Human infections are reported worldwide, but vaccines have been approved only in China and Korea. Orthohantavirus vaccine development has
Joon-Yong Bae +6 more
doaj +3 more sources
Hypopituitarism after Orthohantavirus Infection: What is Currently Known? [PDF]
Viruses, 2019 Several case reports have described hypopituitarism following orthohantavirus infection, mostly following Puumala virus. The pathogenesis of this seemingly rare complication of orthohantavirus infection remains unknown.
Soerajja Bhoelan +7 more
doaj +3 more sources
Orthohantavirus Replication in the Context of Innate Immunity
Viruses, 2023 Orthohantaviruses are rodent-borne, negative-sense RNA viruses that are capable of causing severe vascular disease in humans. Over the course of viral evolution, these viruses have tailored their replication cycles in such a way as to avoid and/or ...
Autumn LaPointe +2 more
doaj +3 more sources
Orthohantavirus Spp. – Review Of Genus [PDF]
Postępy Mikrobiologii, 2021 The infections caused by orthohantaviruses were already known in the Middle Ages as “English sweats.” There are two main diseases caused by these viruses – HPS (hantavirus pulmonary syndrome) and HFRS (hemorrhagic fever with renal syndrome).
Leis Kamil +7 more
doaj +2 more sources
Novel Ozark Orthohantavirus in Hispid Cotton Rats (Sigmodon hispidus), Arkansas, USA
Emerging Infectious Diseases, 2023 We report a novel orthohantavirus, putatively named Ozark orthohantavirus, in hispid cotton rats captured within the Ozark Plateau in Arkansas, USA.
Nathaniel Mull +4 more
doaj +4 more sources
5,6-Dichloro-2-Phenyl-Benzotriazoles: New Potent Inhibitors of Orthohantavirus [PDF]
Viruses, 2020 Orthohantaviruses, previously known as hantaviruses (family Hantaviridae, order Bunyavirales), are emerging zoonoses hosted by different rodent and insectivore species. Orthohantaviruses are transmitted by aerosolized excreta (urine, saliva and feces) of
Giuseppina Sanna +9 more
doaj +4 more sources
Orthohantavirus Pathogenesis and Cell Tropism [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Orthohantaviruses are zoonotic viruses that are naturally maintained by persistent infection in specific reservoir species. Although these viruses mainly circulate among rodents worldwide, spill-over infection to humans occurs. Orthohantavirus infection in humans can result in two distinct clinical outcomes: hemorrhagic fever with renal syndrome (HFRS)
Danny Noack +6 more
openaire +6 more sources
Achievement and Challenges in Orthohantavirus Vaccines. [PDF]
Vaccines (Basel)Orthohantaviruses (also known as hantaviruses) are pathogens that cause two distinct, yet related forms of severe human disease: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). These diseases pose a significant threat to global public health due to their high case fatality rates, which can range from 1% to 50%.
Chai S, Wang L, Du H, Jiang H.
europepmc +4 more sources
One Health Outlook, 2022 Background Orthohantaviruses and leptospira are emerging zoonotic pathogens of high public health significance. The epidemiology of orthohantavirus infections and leptospirosis is similar and presents related clinical pictures in humans.
N. P. Sunil-Chandra +6 more
doaj +1 more source
Hantavirus is Associated With Open Developed Areas and Arid Climates, Highlighting Increased Risk in the Western United States. [PDF]
Transbound Emerg DisIn the United States, hantaviruses can cause hantavirus pulmonary syndrome (HPS) in humans, an acute respiratory illness with a high mortality rate. Most people contract HPS from exposure to infected rodent excrement. The interannual dynamics of hantavirus transmission are tied to both environmental and human‐related factors, including changes in ...
Gorris ME +4 more
europepmc +2 more sources