Serological Evidence of Multiple Zoonotic Viral Infections among Wild Rodents in Barbados [PDF]
Pathogens, 2021 Background: Rodents are reservoirs for several zoonotic pathogens that can cause human infectious diseases, including orthohantaviruses, mammarenaviruses and orthopoxviruses.
Kirk Osmond Douglas +6 more
doaj +6 more sources
Species-specific responses during Seoul orthohantavirus infection in human and rat lung microvascular endothelial cells [PDF]
PLoS Neglected Tropical DiseasesSeoul orthohantavirus (SEOV) is a rat-borne zoonotic virus that is transmitted via inhalation of aerosolized infectious excreta, and can cause hemorrhagic fever with renal syndrome (HFRS) in humans worldwide.
D. Noack +5 more
semanticscholar +5 more sources
Evidence of orthohantavirus and leptospira infections in small mammals in an endemic area of Gampaha district in Sri Lanka [PDF]
One Health Outlook, 2022 Background Orthohantaviruses and leptospira are emerging zoonotic pathogens of high public health significance. The epidemiology of orthohantavirus infections and leptospirosis is similar and presents related clinical pictures in humans.
N. P. Sunil-Chandra +6 more
doaj +2 more sources
First Evidence of Akodon-Borne Orthohantavirus in Northeastern Argentina [PDF]
, 2021 Orthohantaviruses (genus Orthohantavirus, family Hantaviridae) are the etiologic agents of Hantavirus Pulmonary Syndrome in the Americas. In South America, orthohantaviruses are highly diverse and are hosted by sigmodontine rodents (subfamiliy ...
Eliana Burgos +5 more
openalex +4 more sources
Orthohantavirus rodent hosts and genotypes in Southern South America: A narrative review. [PDF]
PLoS Negl Trop DisOrthohantaviruses, family Hantaviridae, are zoonotic agents that pose a significant public health threat, particularly in South America, where they cause severe respiratory illnesses in humans.
Ortiz N +4 more
europepmc +2 more sources
Increased Heparanase Levels in Urine during Acute Puumala Orthohantavirus Infection Are Associated with Disease Severity [PDF]
Viruses, 2022 Old–world orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS), characterized by acute kidney injury (AKI) with transient proteinuria. It seems plausible that proteinuria during acute HFRS is mediated by the disruption of the glomerular ...
Luz E. Cabrera +8 more
doaj +9 more sources
Epidemiological surveillance and phylogenetic diversity of Orthohantavirus hantanense using high-fidelity nanopore sequencing, Republic of Korea. [PDF]
PLoS Negl Trop DisBackground Orthohantavirus hantanense (HTNV) poses a substantial global public health threat due to its role in causing hemorrhagic fever with renal syndrome (HFRS).
Park K +16 more
europepmc +2 more sources
Orthohantavirus Replication in the Context of Innate Immunity [PDF]
Viruses, 2023 Orthohantaviruses are rodent-borne, negative-sense RNA viruses that are capable of causing severe vascular disease in humans. Over the course of viral evolution, these viruses have tailored their replication cycles in such a way as to avoid and/or ...
Autumn LaPointe +2 more
doaj +2 more sources
Achievement and Challenges in Orthohantavirus Vaccines. [PDF]
Vaccines (Basel)Orthohantaviruses (also known as hantaviruses) are pathogens that cause two distinct, yet related forms of severe human disease: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS).
Chai S, Wang L, Du H, Jiang H.
europepmc +2 more sources
Standardization, validation, and comparative evaluation of a convenient surrogate recombinant vesicular stomatitis virus plaque reduction test for quantification of Hantaan orthohantavirus (HTNV) neutralizing antibodies. [PDF]
Virol JHantaan orthohantavirus (HTNV) is responsible for severe hemorrhagic fever with renal syndrome (HFRS), which has a case fatality rate of 1% to 10%. Currently, the inactive vaccine licensed in endemic areas elicit low levels of neutralizing antibodies ...
Wei J +16 more
europepmc +2 more sources