Orthohantavirus Spp. – Review Of Genus [PDF]
The infections caused by orthohantaviruses were already known in the Middle Ages as “English sweats.” There are two main diseases caused by these viruses – HPS (hantavirus pulmonary syndrome) and HFRS (hemorrhagic fever with renal syndrome).
Leis Kamil +7 more
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Molecular evolution and reassortment dynamics of Orthohantavirus hantanense revealed through longitudinal genomic surveillance in the Republic of Korea. [PDF]
Orthohantavirus hantanense (HTNV), a major cause of hemorrhagic fever with renal syndrome (HFRS), remains a public health concern in East Asia. We investigated its evolutionary history, reassortment, and genetic diversity by analyzing 123 complete ...
Park K, Kim J, Kim SG, Kim WK, Song JW.
europepmc +2 more sources
Recovering Immunogenic <i>Orthohantavirus puumalaense</i> N Protein from Pellets of Recombinant <i>Escherichia coli</i>. [PDF]
(1) Background: Hemorrhagic fever with renal syndrome (HFRS) remains a prevalent zoonosis in Eurasia. Orthohantavirus puumalaense (PUUV), carried by bank voles (Myodes glareolus), is the principal zoonotic pathogen of HFRS in this region. Despite ongoing
Andreeva N +16 more
europepmc +2 more sources
Longitudinal study of Orthohantavirus hantanense in Apodemus agrarius and disease risk assessment in the Republic of Korea during 2000-2019. [PDF]
Orthohantavirus hantanense (HTNV) is a zoonotic pathogen transmitted by rodents and the causative agent of hemorrhagic fever with renal syndrome (HFRS) in East Asia.
Klein TA +13 more
europepmc +2 more sources
Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology. [PDF]
Puumala orthohantavirus (PUUV) is an emerging zoonotic virus that was first discovered in the Puumala region of Finland in the early 1980s and is the primary etiological agent of nephropathia epidemica (NE), a milder form of a life-threatening disease ...
Tscherne A +4 more
europepmc +2 more sources
Orthohantaviruses (family Hantaviridae, order Bunyavirales) can cause two serious syndromes in humans: hemorrhagic fever with renal syndrome (HFRS), associated with the Old World orthohantaviruses, and hantavirus cardiopulmonary syndrome (HCPS ...
Tabitha E. Hoornweg +8 more
doaj +2 more sources
Ecological determinants driving orthohantavirus prevalence in small mammals of Europe: a systematic review. [PDF]
Orthohantaviruses are emerging zoonotic pathogens that cause severe human disease and are considered an emerging public health threat globally. Mammalian orthohantaviruses are naturally maintained in rodent species and occasionally in other mammals.
Fabbri D +5 more
europepmc +2 more sources
Pathogenicity and virulence of Rodent-Borne Orthohantaviruses [PDF]
The Orthohantavirus genus in the family Hantaviridae includes viruses that cause zoonotic diseases in humans known as hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Exposure of humans to these viruses occurs through
Shannon L. Taylor +3 more
doaj +2 more sources
Interactions Between Hantavirus Nucleoprotein and Glycoproteins: A Quantitative Fluorescence Microscopy Study [PDF]
Orthohantaviruses are tri-segmented negative-sense RNA viruses that can cause severe pathologies in humans. Currently, limited information exists on the molecular interactions driving orthohantavirus assembly in infected cells.
Amit Koikkarah Aji +2 more
doaj +2 more sources
Molecular Evolution and Zoonotic Potential of Muju Virus (Orthohantavirus puumalaense) in Craseomys regulus, Republic of Korea [PDF]
Orthohantavirus puumalaense causes hemorrhagic fever with renal syndrome in Europe, with Puumala virus (PUUV) as its primary representative. Muju virus (MUJV), harbored by Craseomys regulus, an Arvicolinae rodent species endemic to the Republic of Korea (
Park K +12 more
europepmc +2 more sources

