Serological study of vaccinia virus reservoirs in areas with and without official reports of outbreaks in cattle and humans in São Paulo, Brazil [PDF]
Vaccinia virus (VACV), the etiological agent of an exanthematic disease, has been associated with several bovine outbreaks in Brazil since the end of the global vaccination campaign against smallpox. It was previously believed that the vaccine virus used
Acácia Ferreira Vicente+13 more
core +1 more source
Antigen‐presenting extracellular vesicles (AP‐EVs) express peptide‐major histocompatibility complex (pMHC) class I, costimulatory molecules, and IL‐2. These AP‐EVs accumulated in the tumor microenvironment, promoting the expansion of IFN‐γ+ CD8+ T cells and decreasing exhausted CD8+ T cells, thereby enhancing the anti‐tumor immune response.
Xiabing Lyu+12 more
wiley +1 more source
Co-Circulating Monkeypox and Swinepox Viruses, Democratic Republic of the Congo, 2022
In September 2022, deaths of pigs manifesting pox-like lesions caused by swinepox virus were reported in Tshuapa Province, Democratic Republic of the Congo. Two human mpox cases were found concurrently in the surrounding community.
Thierry Kalonji+33 more
doaj +1 more source
Orthopoxvirus Infections: Epidemiology, Clinical Picture, and Diagnostics (Scientific Review)
Lack of immunity among the population against pathogenic orthopoxviruses and an increased number of these infections human cases testify to the need of development of the rapid high-sensitive methods for species-specific orthopoxvirus diagnostics.
E. V. Gavrilova+2 more
doaj +1 more source
New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections.
Currently, the spectrum of agents against orthopoxviruses, in particular smallpox, is very narrow. Despite the fact that smallpox is well controlled, there is, for many reasons, a real threat of epidemics associated with this or a similar virus. In order
E. Suslov+10 more
semanticscholar +1 more source
Microparasites and their potential impact on the population dynamics of small cetaceans from South America: a brief review. Document SC/59/DW8, Scientific Committee, International Whaling Commission, Anchorage, Alaska, 4-14 May 2007 [PDF]
We briefly review the pathology, epidemiology and molecular biology of cetacean viruses (including morbilli, papilloma and pox) and Brucella spp. encountered in South America.
Barrett, T.+6 more
core
A REVIEW OF MONKEYPOX DISEASE AND FUTURE TREATMENT OPTIONS [PDF]
The Monkeypox virus (MPXV) causative agent for Monkeypox disease resembles a smallpox-like illness and can lead to a number of serious medical issues in humans.
MISRA, SAURAV, SHUKLA, AJAY KUMAR
core +1 more source
Health Under Siege: Mpox and the Populations on the Ethiopia–Somalia–Kenya Border
Public Health Challenges, Volume 4, Issue 2, June 2025.
Abdisalam Yusuf Ali+3 more
wiley +1 more source
The inability of vaccinia virus A33R protein to form intermolecular disulfide-bonded homodimers does not affect the production of infectious extracellular virus [PDF]
The orthopoxvirus protein A33 forms a disulfide-bonded high molecular weight species that could be either a homodimer or a heteromultimer. The protein is a major target for neutralizing antibodies and the majority of antibodies raised against A33 only ...
Chan, Winnie M.+2 more
core +1 more source
Monkeypox Virus: WHO's Second Public Health Emergency of International Concern Within 2 Years
The figure shows examples of zoonotic diseases and their affected populations. The red arrows indicate the path of monkeypox virus infections first from a wild animal reservoir (rodents, squirrels) as a zoonosis mostly to children in central and west Africa, followed by the 2022/3 epidemic with human‐to‐human transmission in men having sex with men and
Harald Brüssow
wiley +1 more source