Results 121 to 130 of about 13,277 (283)

Effects of georeferencing effort on mapping monkeypox case distributions and transmission risk [PDF]

, 2012
Background Maps of disease occurrences and GIS-based models of disease transmission risk are increasingly common, and both rely on georeferenced diseases data.
Carroll Darin S, Damon Inger K, Hughes Christine M, Karem Kevin, Lash R, Nakazawa Yoshinori, Peterson A   +6 more
core   +3 more sources

Modeling the Impact of Double‐Dose Vaccination and Saturated Transmission Dynamics on Mpox Control

Engineering Reports, Volume 7, Issue 5, May 2025.
The dynamics of the monkeypox disease in the population. ABSTRACT This study constructs a compartmental model that incorporates the dynamics of implementing a double‐dose vaccination for the Mpox disease. The study further explores the pattern of saturated transmission dynamics of the Mpox disease.
Fredrick Asenso Wireko, Joshua Nii Martey, Isaac Kwasi Adu, Bright Emmanuel Owusu, Sebastian Ndogum, Joshua Kiddy K. Asamoah   +5 more
wiley   +1 more source

Serological Response to Mpox and Direct Virus Detection in Asymptomatic Patient Prior to the First Diagnosed Case: A Retrospective Study of the 2022 Montpellier Epidemic

Journal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT The Mpox (formerly monkeypox) outbreak in 2022 presented unprecedented challenges, including widespread transmission in non‐endemic regions, particularly among men who have sex with men. This study examines Mpox infections in Montpellier, France, focusing on diagnostic testing, serological profiles, and potential asymptomatic cases, based on ...
Steven Henry, Maeliss Champagne, Ahidjo Ayouba, Martine Peeters, Leo‐Pol Rio, Marie Bistoquet, Carmen Alcocer Cordellat, Sylvain Godreuil, Edouard Tuaillon, Vincent Foulongne   +9 more
wiley   +1 more source

Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR

bioRxiv, 2020
The antiviral protein kinase R (PKR) is an important host restriction factor, which poxviruses must overcome to productively infect host cells. To inhibit PKR, many poxviruses encode a pseudosubstrate mimic of the alpha subunit of eukaryotic translation ...
Chorong Park, Chen Peng, M. J. Rahman, Sherry L. Haller, L. Tazi, Greg Brennan, S. Rothenburg   +6 more
semanticscholar   +1 more source

Monkeypox Virus Subverts the Inflammatory Response of Macrophages at the Maternal‐Fetal Interface

Journal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT Monkeypox is a viral zoonosis caused by the monkeypox virus (MPXV). Although the virus was identified decades ago, human immunity to MPXV infection has not been widely characterized. During MPXV infection, macrophages are recruited at the site of infection and are thought to contribute to the spread of the virus.
Jonatane Andrieu, Margaux Valade, Nathalie Wurtz, Marion Lebideau, Florence Bretelle, Bernard La Scola, Jean‐Louis Mège, Soraya Mezouar   +7 more
wiley   +1 more source

Molecular Detection and Characterization of the First Cowpox Virus Isolate Derived from a Bank Vole

Viruses, 2019
Cowpox virus (CPXV) is a zoonotic orthopoxvirus (OPV) that infects a wide range of mammals. CPXV-specific DNA and antibodies were detected in different vole species, such as common voles (Microtus arvalis) and bank voles (Myodes glareolus).
Kathrin Jeske, Saskia Weber, Florian Pfaff, Christian Imholt, Jens Jacob, Martin Beer, Rainer G. Ulrich, Donata Hoffmann   +7 more
doaj   +1 more source

Recombinant viruses as tools to induce protective cellular immunity against infectious diseases [PDF]

, 2010
Infections by intracellular pathogens such as viruses, some bacteria and many parasites, are cleared in most cases after activation of specific T cellular immune responses that recognize foreign antigens and eliminate infected cells.
Alexandre Vieira Machado, Braulia Costa Caetano, Carolina Damas Rocha, Oscar Bruña-Romero   +3 more
core   +2 more sources

Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex [PDF]

, 2011
VACV gene C16L encodes a 37-kDa protein that is highly conserved in orthopoxviruses and functions as an immunomodulator. Intranasal infection of mice with a virus lacking C16L (vΔC16) induced less weight loss, fewer signs of illness and increased ...
Peters, Nicholas Edward, Peters, Nicholas Edward   +1 more
core   +1 more source

A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies

Exploration, Volume 5, Issue 2, April 2025.
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang, Ailan Xu, Lin Guan, Yong Tang, Guangshuai Chai, Junya Feng, Yueqi Wu, Maochen Li, Chuxie Zhang, Xiaojing Liu, Xiaolong Xu, Qingquan Liu, Lihua Song, Yigang Tong, Renald Blundell, Huahao Fan   +15 more
wiley   +1 more source

The Origin of the Variola Virus

Viruses, 2015
The question of the origin of smallpox, one of the major menaces to humankind, is a constant concern for the scientific community. Smallpox is caused by the agent referred to as the variola virus (VARV), which belongs to the genus Orthopoxvirus.
Igor V. Babkin, Irina N. Babkina
doaj   +1 more source