Results 121 to 130 of about 11,818 (284)

Public Health Threat of New, Reemerging, and Neglected Zoonoses in the Industrialized World [PDF]

open access: yes, 2010
Microbiologic infections acquired from animals, known as zoonoses, pose a risk to public health. An estimated 60% of emerging human pathogens are zoonotic. Of these pathogens, >71% have wildlife origins.
Cutler, S.J.   +2 more
core   +4 more sources

Recombinant Orthopoxvirus Primes Colon Cancer for Checkpoint Inhibitor and Cross-Primes T Cells for Antitumor and Antiviral Immunity

open access: yesMolecular Cancer Therapeutics, 2020
Although it is known that oncolytic viruses can inflame and recruit immune cells to otherwise immunosuppressed tumor microenvironments, the influence of the antiviral immune response on antitumor immunity is less clear across viral platforms and tumor ...
Sang-In Kim   +11 more
semanticscholar   +1 more source

Monkeypox: Prevention Strategies and Challenges: Updated Review

open access: yesHealth Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims The mpox virus, sometimes known as MPXV, is the cause of the disease mpox. The Monkeypox virus is a different Poxviridae family member from the orthopoxvirus (OPXV) group. Clades I and II are the two varieties of the Monkeypox virus.
Abate Wondesen Tsige   +1 more
wiley   +1 more source

New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections.

open access: yesRSC Medicinal Chemistry, 2020
Currently, the spectrum of agents against orthopoxviruses, in particular smallpox, is very narrow. Despite the fact that smallpox is well controlled, there is, for many reasons, a real threat of epidemics associated with this or a similar virus. In order
E. Suslov   +10 more
semanticscholar   +1 more source

Direct delivery of immune modulators to tumour‐infiltrating lymphocytes using engineered extracellular vesicles

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 4, April 2025.
Antigen‐presenting extracellular vesicles (AP‐EVs) express peptide‐major histocompatibility complex (pMHC) class I, costimulatory molecules, and IL‐2. These AP‐EVs accumulated in the tumor microenvironment, promoting the expansion of IFN‐γ+ CD8+ T cells and decreasing exhausted CD8+ T cells, thereby enhancing the anti‐tumor immune response.
Xiabing Lyu   +12 more
wiley   +1 more source

Human Monkeypox in Sierra Leone after 44-Year Absence of Reported Cases

open access: yesEmerging Infectious Diseases, 2019
We note the reemergence of human monkeypox in Sierra Leone following a 44-year absence of reported disease. The persons affected were an 11-month-old boy and, several years later, a 35-year-old man.
Mary G. Reynolds   +14 more
doaj   +1 more source

M148R and M149R are two virulence factors for myxoma virus pathogenesis in the European rabbit [PDF]

open access: yes, 2008
Myxoma virus (MYXV), a member of the Poxviridae family, is the agent responsible for myxomatosis, a fatal disease in the European rabbit (Oryctolagus cuniculus).
Bertagnoli, Stéphane   +4 more
core   +4 more sources

Health Under Siege: Mpox and the Populations on the Ethiopia–Somalia–Kenya Border

open access: yes
Public Health Challenges, Volume 4, Issue 2, June 2025.
Abdisalam Yusuf Ali   +3 more
wiley   +1 more source

Serologic Evidence of Orthopoxvirus Infection in Buffaloes, Brazil

open access: yesEmerging Infectious Diseases, 2011
To the Editor: Since 1999, several exanthematous vaccinia virus (VACV) outbreaks affecting dairy cattle and rural workers have been reported in Brazil (1,2). VACV, the prototype of the genus Orthopoxvirus (OPV), exhibits serologic cross-reactivity with other OPV species and was used during the World Health Organization smallpox eradication campaign (3).
Cairo H.S. de Oliveira   +10 more
openaire   +4 more sources

Insights into poxviruses: virology and vaccines

open access: yesActa Virologica
Due to the successful eradication of smallpox worldwide and the cessation of smallpox vaccination campaign in 1980, the human population seems to be more susceptible to poxvirus infection.
Adriana Manuka   +5 more
doaj   +1 more source

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