Results 101 to 110 of about 9,580 (245)

Seasonality of human orthopoxvirus infections

open access: yes, 2022
Variola infections (smallpox) showed seasonality in temperate climates. This sharp seasonality (peaking in the Winter-Spring) may have important ramifications for control and elimination of human monkeypox (MPX) and should be considered in planning public health response.
Andrew Lover, Andrew Noymer
openaire   +1 more source

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 4, Page 829-837, April 2026.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei   +9 more
wiley   +1 more source

Non-Human Primate Models of Orthopoxvirus Infections

open access: yes, 2014
Smallpox, one of the most destructive diseases, has been successfully eradicated through a worldwide vaccination campaign. Since immunization programs have been stopped, the number of people with vaccinia virus induced immunity is declining.
Kerstin Mätz-Rensing   +2 more
core   +1 more source

Mpox in South Asia: A Narrative Review on Epidemiology, Preparedness, and Preventive Strategies

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Monkeypox (Mpox), due to its growing global concern, was declared a public health emergency of worldwide concern by the World Health Organization in August 2024. The monkeypox virus (MPXV), once limited to African regions, has now spread to South Asia, including Pakistan, India, Nepal, and Sri Lanka, and there have been ...
Jannatul Mawa   +5 more
wiley   +1 more source

Orthopoxvirus Genome Evolution: The Role of Gene Loss

open access: yes, 2010
Poxviruses are highly successful pathogens, known to infect a variety of hosts. The family Poxviridae includes Variola virus, the causative agent of smallpox, which has been eradicated as a public health threat but could potentially reemerge as a ...
Elliot J. Lefkowitz   +3 more
core   +1 more source

Evaluation and Clinical Validation of Pan‐Specific and Clade‐Specific Diagnostic Real‐Time PCR Assays for Monkeypox Virus

open access: yesJournal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Human mpox, formerly known as monkeypox, has twice been declared a Public Health Emergency of International Concern (PHEIC) by the World Health Organization, in 2022 and 2024. Despite this, global access to rapid, reliable diagnostics remains limited, hindering outbreak control and equitable clinical response. To address this gap, we developed
Hong Chang   +8 more
wiley   +1 more source

OPVanno: Orthopoxvirus annotation and assembly pipeline.

open access: yes
<p>OPVanno: Orthopoxvirus annotation and assembly pipeline.</p ...
Pfaff, Florian, Kastner, Georg
core   +1 more source

Orthopoxvirus variola infection of Cynomys ludovicianus (North American Black tailed prairie dog)

open access: yes, 2013
Since the eradication of Smallpox, researchers have attempted to study Orthopoxvirus pathogenesis and immunity in animal models in order to correlate results human smallpox.
Braden, Zach H.   +8 more
core   +1 more source

Short-Lived Neutralizing Antibody Responses to Monkeypox Virus in Smallpox Vaccine–Naive Persons after JYNNEOS Vaccination

open access: yesEmerging Infectious Diseases
JYNNEOS, a third-generation smallpox vaccine, is integral to monkeypox virus (MPXV) control efforts, but the durability of this modified vaccinia Ankara–Bavarian Nordic (MVA-BN) vaccine’s effectiveness is undefined.
Kara Phipps   +8 more
doaj   +1 more source

IgA Antibodies Reveal Covert Infection With Mpox Virus in People Living With HIV in the Community: A Prospective Longitudinal Cohort Survey

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This study identified covert infection of MPXV among people living with HIV and MPXV‐IgA was the effective indicator. The combined use of two antigen protein set of MPXV (B6R plus E8L and E8L plus H3L) yield IgA test results comparable to those obtained with the MPXV.
Rui Song   +12 more
wiley   +1 more source

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