Results 101 to 110 of about 9,580 (245)
Seasonality of human orthopoxvirus infections
Variola infections (smallpox) showed seasonality in temperate climates. This sharp seasonality (peaking in the Winter-Spring) may have important ramifications for control and elimination of human monkeypox (MPX) and should be considered in planning public health response.
Andrew Lover, Andrew Noymer
openaire +1 more source
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei +9 more
wiley +1 more source
Non-Human Primate Models of Orthopoxvirus Infections
Smallpox, one of the most destructive diseases, has been successfully eradicated through a worldwide vaccination campaign. Since immunization programs have been stopped, the number of people with vaccinia virus induced immunity is declining.
Kerstin Mätz-Rensing +2 more
core +1 more source
Mpox in South Asia: A Narrative Review on Epidemiology, Preparedness, and Preventive Strategies
ABSTRACT Background and Aims Monkeypox (Mpox), due to its growing global concern, was declared a public health emergency of worldwide concern by the World Health Organization in August 2024. The monkeypox virus (MPXV), once limited to African regions, has now spread to South Asia, including Pakistan, India, Nepal, and Sri Lanka, and there have been ...
Jannatul Mawa +5 more
wiley +1 more source
Orthopoxvirus Genome Evolution: The Role of Gene Loss
Poxviruses are highly successful pathogens, known to infect a variety of hosts. The family Poxviridae includes Variola virus, the causative agent of smallpox, which has been eradicated as a public health threat but could potentially reemerge as a ...
Elliot J. Lefkowitz +3 more
core +1 more source
ABSTRACT Human mpox, formerly known as monkeypox, has twice been declared a Public Health Emergency of International Concern (PHEIC) by the World Health Organization, in 2022 and 2024. Despite this, global access to rapid, reliable diagnostics remains limited, hindering outbreak control and equitable clinical response. To address this gap, we developed
Hong Chang +8 more
wiley +1 more source
OPVanno: Orthopoxvirus annotation and assembly pipeline.
<p>OPVanno: Orthopoxvirus annotation and assembly pipeline.</p ...
Pfaff, Florian, Kastner, Georg
core +1 more source
Orthopoxvirus variola infection of Cynomys ludovicianus (North American Black tailed prairie dog)
Since the eradication of Smallpox, researchers have attempted to study Orthopoxvirus pathogenesis and immunity in animal models in order to correlate results human smallpox.
Braden, Zach H. +8 more
core +1 more source
JYNNEOS, a third-generation smallpox vaccine, is integral to monkeypox virus (MPXV) control efforts, but the durability of this modified vaccinia Ankara–Bavarian Nordic (MVA-BN) vaccine’s effectiveness is undefined.
Kara Phipps +8 more
doaj +1 more source
This study identified covert infection of MPXV among people living with HIV and MPXV‐IgA was the effective indicator. The combined use of two antigen protein set of MPXV (B6R plus E8L and E8L plus H3L) yield IgA test results comparable to those obtained with the MPXV.
Rui Song +12 more
wiley +1 more source

