Results 81 to 90 of about 9,580 (245)

Anti-orthopoxvirus antibody production.

open access: yes, 2013
Orthopoxvirus specific ELISA to detect total IgG. The average value per infection group is shown here. The reported OD-COV (cutoff value) corresponds to the value above the average signal of the negative control wells plus two standard deviations.
Paul N. Hudson (190325)   +11 more
core   +1 more source

New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections.

open access: yesRSC Medicinal Chemistry, 2020
Currently, the spectrum of agents against orthopoxviruses, in particular smallpox, is very narrow. Despite the fact that smallpox is well controlled, there is, for many reasons, a real threat of epidemics associated with this or a similar virus. In order
E. Suslov   +10 more
semanticscholar   +1 more source

Effect of Monkeypox Virus Preparation on the Lethality of the Intravenous Cynomolgus Macaque Model

open access: yesViruses, 2022
For over two decades, researchers have sought to improve smallpox vaccines and also develop therapies to ensure protection against smallpox or smallpox-like disease.
Eric M. Mucker   +5 more
doaj   +1 more source

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade   +5 more
wiley   +1 more source

Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model

open access: yesMolecular Therapy: Oncolytics, 2020
Oncolytic virotherapy represents a promising approach for treating recurrent and/or drug-resistant ovarian cancer. However, its successful application in the clinic has been hampered by rapid immune-mediated clearance, which reduces viral delivery to the
Mohamed Hammad   +13 more
semanticscholar   +1 more source

Sero-Epidemiological Survey of Orthopoxvirus in Stray Cats and in Different Domestic, Wild and Exotic Animal Species of Central Italy

open access: yesViruses, 2021
Orthpoxvirus infection can spread more easily in a population with a waning immunity with the subsequent emergence/re-emergence of the viruses pertaining to this genus.
Francesca Rosone   +7 more
doaj   +1 more source

Mpox Awareness and Infection Control Practices Among Hospital Nurses and Healthcare Workers in Bangladesh

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
This study summarizes the KAP measures regarding Mpox among healthcare workers in Bangladesh. A total of 110 participants were included, with 60.9% having prior awareness, mainly through social media. Overall, 47.3% demonstrated good knowledge, whereas positive attitudes (86.4%) and appropriate practices (82.7%) were observed.
Hemayet Hossain   +8 more
wiley   +1 more source

Monkeypox Virus in Animals: Current Knowledge of Viral Transmission and Pathogenesis in Wild Animal Reservoirs and Captive Animal Models

open access: yesViruses, 2023
Mpox, formerly called monkeypox, is now the most serious orthopoxvirus (OPXV) infection in humans. This zoonotic disease has been gradually re-emerging in humans with an increasing frequency of cases found in endemic areas, as well as an escalating ...
Elizabeth A. Falendysz   +3 more
doaj   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

open access: yesAdvanced Intelligent Systems, Volume 8, Issue 5, May 2026.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken   +4 more
wiley   +1 more source

The impact of antigenic distance on Orthopoxvirus Vaccination and Mpox Infection for cross-protective immunity

open access: yesmedRxiv
Immunological memory mediates rapid protection following infection or vaccination including heterologous exposure. However, cross-reactive memory responses in humans remain poorly characterized.
Jameson Crandell   +23 more
semanticscholar   +1 more source

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