Results 81 to 90 of about 2,721 (157)

Orthopoxvirus variola infection of Cynomys ludovicianus (North American Black tailed prairie dog)

, 2013
Since the eradication of Smallpox, researchers have attempted to study Orthopoxvirus pathogenesis and immunity in animal models in order to correlate results human smallpox.
Braden, Zach H., Patel, Nishi, Li, Yu, Olson, Victoria A., Abel, Jason, Karem, Kevin L., Damon, Inger K., Carroll, Darin S., Smith, Scott K.   +8 more
core   +1 more source

N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides:  Identification of Novel Orthopoxvirus Egress Inhibitors

, 2016
A series of novel, potent orthopoxvirus egress inhibitors was identified during high-throughput screening of the ViroPharma small molecule collection.
Marc S. Collett (2497417), Earl R. Kern (2497402), Gerry Rhodes (2497420), Christopher J. Burns (685703), Daniel C. Pevear (2497423), Robert Jordan (346146), Robert O. Baker (2497408), Thomas R. Bailey (2497399), John W. Huggins (202153), Kathy A. Keith (2497426), Sanjeev Tohan (2497405), Dennis Hruby (2497396), Susan R. Rippin (1443640), Dongcheng Dai (2497414), Elizabeth Opsitnick (2497411), Guang Yang (154978)   +15 more
core   +1 more source

Short-Lived Neutralizing Antibody Responses to Monkeypox Virus in Smallpox Vaccine–Naive Persons after JYNNEOS Vaccination

Emerging Infectious Diseases
JYNNEOS, a third-generation smallpox vaccine, is integral to monkeypox virus (MPXV) control efforts, but the durability of this modified vaccinia Ankara–Bavarian Nordic (MVA-BN) vaccine’s effectiveness is undefined.
Kara Phipps, Jennifer Yates, Jessica Pettit, Sean Bialosuknia, Danielle Hunt, Alan P. DuPuis, Anne Payne, William Lee, Kathleen A. McDonough   +8 more
doaj   +1 more source

Identity between Orthopoxviruses based on the Poxvirus, Chordopoxvirus and Orthopoxvirus gene families.

, 2013
The lower left shows the identity on nucleic acid level, while the upper right shows the identity on amino acid level. The phylogenetic tree on the left is also based on a DNA sequence alignment of the Poxvirus, Chordopoxvirus and Orthopoxvirus gene ...
Piotr Wojtek Dabrowski (320443), Aleksandar Radonić (142207), Andreas Kurth (34946), Andreas Nitsche (12987)   +3 more
core   +1 more source

Abstract Supplement HIV Glasgow 8–11 November 2026, Glasgow, UK/Virtual

Journal of the International AIDS Society, Volume 29, Issue S6, November 2026.
wiley   +1 more source

Genomic Insights into the Spread of Vaccinia Virus Strain Cantagalo to Rural Regions of Northeastern Brazil

Viruses
Vaccinia virus strain Cantagalo (CTGV) causes a pustular disease in dairy cows and milkers in Brazil. Outbreaks in several states have been frequently reported, but the full genome sequence and genomic analysis of isolates from the Northeast region have ...
Maria Júlia Cadrieskt-Ribeiro, Matheus Nobrega Luques, Samuel Hir, Pedro Lucas O. Correia, Régis Linhares Oliveira, Carolina Maciel Neves, Keilla Maria P. Silva, Mayara Matias O. M. da Costa, Diego Arruda Falcão, Luciana Bahiense da Costa, Arabela Leal S. Mello, Jussara Lagos O. Silveira, Clarissa R. Damaso   +12 more
doaj   +1 more source

Vaccinia and Monkeypox Virus-Neutralizing Antibodies in People Living with HIV: A Serological Study in a Orthopoxvirus-Endemic, Low-Income Region in Brazil

Pathogens
Co-infections of Orthopoxviruses (OPVs), such as vaccinia virus (VACV) and monkeypox virus (MPXV), and the human immunodeficiency virus (HIV) can be associated with severe outcomes.
Thyago José Silva, Ana Gabriella Stoffella-Dutra, Victor Lacerda Gripp, Pollyana R. C. Gorgens, Iago José da Silva Domingos, Pedro Henrique Bastos e Silva, Bruna Caroline Chaves-Garcia, Erna Geessien Kroon, Etel Rocha-Vieira, Giliane de Souza Trindade, Danilo Bretas de Oliveira   +10 more
doaj   +1 more source

Insights into poxviruses: virology and vaccines

Acta Virologica
Due to the successful eradication of smallpox worldwide and the cessation of smallpox vaccination campaign in 1980, the human population seems to be more susceptible to poxvirus infection.
Adriana Manuka, Irsida Mehmeti, Antonia Radaelli, Eduart Hashorva, Carlo Zanotto, Carlo De Giuli Morghen   +5 more
doaj   +1 more source

ACAM2000 vaccine safety and immunogenicity considerations for smallpox and mpox

Expert Review of Vaccines
Introduction Smallpox, eradicated globally in 1980, remains a major biodefense concern due to retained Variola virus stocks and the absence of population immunity following cessation of routine vaccination. Monkeypox virus (MPXV), a related orthopoxvirus,
Vanja Komlenovic, James McCarty, David Cassie, Ravi Anantha, Kevin Yeo, Mario Rodriguez, Bojan Drobic   +6 more
doaj   +1 more source

Rapid and High-Throughput pan-Orthopoxvirus Detection and Identification using PCR and Mass

, 2009
The genus Orthopoxvirus contains several species of related viruses, including the causative agent of smallpox (Variola virus). In addition to smallpox, several other members of the genus are capable of causing human infection, including monkeypox ...
Karl Rudnick, Aysegul Nalca, Joseph A. Ecker, Brian Libby, Mark W. Eshoo, Thuy-trang D. Pennella, Anjali Desai, Thomas A. Hall, Emily K. Moradi, Chris A. Whitehouse, Scott Zoll, David D. Duncan   +11 more
core