Results 61 to 70 of about 2,721 (157)

Hazard Characterization of Modified Vaccinia Virus Ankara Vector: What Are the Knowledge Gaps?

Viruses, 2017
Modified vaccinia virus Ankara (MVA) is the vector of choice for human and veterinary applications due to its strong safety profile and immunogenicity in vivo.
Malachy I. Okeke, Arinze S. Okoli, Diana Diaz, Collins Offor, Taiwo G. Oludotun, Morten Tryland, Thomas Bøhn, Ugo Moens   +7 more
doaj   +1 more source

Mpox Airborne Transmission: A Systematic Review

Reviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Since May 2022, mpox has been reported across multiple nonendemic regions, with concurrent outbreaks in diverse geographic settings, raising concerns about broader international spread. However, evidence regarding the risk of airborne transmission remains limited.
Lucas Ferreira Theotonio dos Santos, Leonardo Javier Arcuri, Viviane Aparecida R. Sant’Anna, Patrícia Campos Couto, Guilherme de Paula P. Schettino, Luiz Vicente Rizzo, Henrique Andrade R. Fonseca   +6 more
wiley   +1 more source

OPVanno: Orthopoxvirus annotation and assembly pipeline.

<p>OPVanno: Orthopoxvirus annotation and assembly pipeline.</p ...
Pfaff, Florian, Kastner, Georg
core   +1 more source

One‐Pot RPA‐CRISPR/Cas12a Assay With Visual Readout for the Ultra‐Specific Detection of Monkeypox Virus Clade I

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
This study established a rapid RPA‐CRISPR/Cas12a assay for MPXV clade I detection, achieving an LOD95 of 27.16 copies/μL within 40 min. The assay exhibited no cross‐reactivity with MPXV clade II or other orthopoxviruses. Under simulated conditions, the assay detected more low‐concentration plasmid‐spiked samples than quantitative polymerase chain ...
Boyi Li, Luyao Liu, Kaikai Jin, Zanheng Huang, Tianyi Zhang, Rong Gao, Huanxin Chen, Lijuan Niu, Changqi Fan, Haili Zhang, Pei Huang, Hualei Wang   +11 more
wiley   +1 more source

Data from: Novel orthopoxvirus infection in an Alaska resident

, 2017
Background. Human infection by orthopoxviruses is being reported with increasing frequency, attributed in part to the cessation of smallpox vaccination and concomitant waning of population-level immunity.
Patel, Nishi, Mauldin, Matthew R., Li, Yu, Burgado, Jillybeth, Fowler, Nisha, Goldsmith, Cynthia S., Springer, Yuri P., McCollum, Andrea M., Olson, Link E., Doty, Jeffrey B., Castrodale, Louisa J., Satheshkumar, Panayampalli S., Wilkins, Kimberly, Emerson, Ginny L., McLaughlin, Joseph B., Hsu, Chris H., Gao, JinXin, Reynolds, Mary G., Cooper, Michael, Davidson, Whitni, Werle, Zach   +20 more
core   +1 more source

Conservation and Variation in Orthopoxvirus Genome Structure

Journal of General Virology, 1979
Orthopoxvirus DNA from representative strains of rabbitpox, vaccinia, monkeypox, variola, cowpox and ectromelia viruses was analysed by cleavage with restriction endonucleases HindIII, XhoI or SmaI. Genome mol. wt. vary from about 120 x 10(6) for rabbitpox to about 145 x 10(6) for cowpox.
M, Mackett, L C, Archard
openaire   +2 more sources

Identification of Repurposed Drugs Against Monkeypox Virus Through Comprehensive Virtual Screening

Biotechnology Journal, Volume 21, Issue 8, August 2026.
Graphical Abstract and Lay Summary By combining interspecies protein analysis with advanced virtual screening, this study identifies potent repurposed drug candidates—including vindesine and LY2090314—targeting mpox DNA topoisomerase and polymerase. This workflow provides a rapid, practical framework for antiviral discovery against emerging infectious ...
Taeho Yu, Woo Dae Jang, Sang Yup Lee
wiley   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman, Karan Goel, Fernando Berton Zanchi, Aykut Ozdarendeli, Somdutt Mujwar, Ahmet E. Yetiman, Ozkan Fidan   +6 more
wiley   +1 more source

Whole genome sequencing of recombinant viruses obtained from co-infection and superinfection of Vero cells with modified vaccinia virus ankara vectored influenza vaccine and a naturally occurring cowpox virus

Frontiers in Immunology
Modified vaccinia virus Ankara (MVA) has been widely tested in clinical trials as recombinant vector vaccine against infectious diseases and cancers in humans and animals.
Diana Diaz-Cánova, Ugo Moens, Annika Brinkmann, Andreas Nitsche, Malachy Ifeanyi Okeke   +4 more
doaj   +1 more source

Knowledge and Attitudes of Healthcare Workers Toward the Re‐Emergence of Human Monkeypox Virus Infection in Public Health Facilities in the Central Ethiopia Region: An Online Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Human monkeypox (mpox) is a re‐emerging zoonotic viral disease in Africa. Despite recent reports in Ethiopia, no studies have assessed healthcare workers' (HCWs) knowledge and attitudes in the Central Ethiopia Region. This study aimed to determine HCWs knowledge and attitudes toward the re‐emergence of mpox in public health
Yilma Markos Larebo, Zerfework Debebe Argago, Markos Selamu Jifar, Abebe Alemu Anshebo, Sujit Kumar Behera, Natarajan Gopalan   +5 more
wiley   +1 more source