Results 61 to 70 of about 7,603 (130)

Genomic Insights into the Spread of Vaccinia Virus Strain Cantagalo to Rural Regions of Northeastern Brazil

Viruses
Vaccinia virus strain Cantagalo (CTGV) causes a pustular disease in dairy cows and milkers in Brazil. Outbreaks in several states have been frequently reported, but the full genome sequence and genomic analysis of isolates from the Northeast region have ...
Maria Júlia Cadrieskt-Ribeiro, Matheus Nobrega Luques, Samuel Hir, Pedro Lucas O. Correia, Régis Linhares Oliveira, Carolina Maciel Neves, Keilla Maria P. Silva, Mayara Matias O. M. da Costa, Diego Arruda Falcão, Luciana Bahiense da Costa, Arabela Leal S. Mello, Jussara Lagos O. Silveira, Clarissa R. Damaso   +12 more
doaj   +1 more source

Dynamics of Pathological and Virological Findings During Experimental Calpox Virus Infection of Common Marmosets (Callithrix jacchus)

Viruses, 2017
Experimental intranasal infection of marmosets (Callithrix jacchus) with calpox virus results in fatal disease. Route and dose used for viral inoculation of the test animals mimics the natural transmission of smallpox, thus representing a suitable model ...
Anne Schmitt, Li Lin Gan, Ahmed Abd El Wahed, Tingchuan Shi, Heinz Ellerbrok, Franz-Josef Kaup, Christiane Stahl-Hennig, Kerstin Mätz-Rensing   +7 more
doaj   +1 more source

Cowpox with Severe Generalized Eruption, Finland

Emerging Infectious Diseases, 2003
Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies.
Paula M. Pelkonen, Kyllikki Tarvainen, Arja Hynninen, Eva R.K. Kallio, Heikki Henttonen, Airi Palva, Antti Vaheri, Olli Vapalahti   +7 more
doaj   +1 more source

ACAM2000 vaccine safety and immunogenicity considerations for smallpox and mpox

Expert Review of Vaccines
Introduction Smallpox, eradicated globally in 1980, remains a major biodefense concern due to retained Variola virus stocks and the absence of population immunity following cessation of routine vaccination. Monkeypox virus (MPXV), a related orthopoxvirus,
Vanja Komlenovic, James McCarty, David Cassie, Ravi Anantha, Kevin Yeo, Mario Rodriguez, Bojan Drobic   +6 more
doaj   +1 more source

Discovery of the nucleoside analogue FMAU as a broad-spectrum anti-orthopoxvirus inhibitor in vitro and in vivo using a structure-guided hit expansion strategy

Emerging Microbes and Infections
Mpox remains a critical public health threat worldwide, and currently available therapeutics against orthopoxvirus infections remain very limited. In this study, we identified 2'-deoxy-2'-fluoro-5-methyl-1-β-D-arabinofuranosyluracil (FMAU) as a broad ...
Tingting Zheng, Yong Feng, Chang Xu, Arnaud Fondjo Kouam, Shiman Chen, Farkhod Eshboev, Yingxia Liu, Fuxiang Wang, Yang Yang, Jianxun Qi, Lifeng Fu   +10 more
doaj   +1 more source

Human Monkeypox in Sierra Leone after 44-Year Absence of Reported Cases

Emerging Infectious Diseases, 2019
We note the reemergence of human monkeypox in Sierra Leone following a 44-year absence of reported disease. The persons affected were an 11-month-old boy and, several years later, a 35-year-old man.
Mary G. Reynolds, Nadia Wauquier, Yu Li, Panayampalli Subbian Satheshkumar, Lansana D. Kanneh, Benjamin Monroe, Jacob Maikere, Gbessay Saffa, Jean-Paul Gonzalez, Joseph Fair, Darin S. Carroll, Amara Jambai, Foday Dafae, Sheik Humarr Khan, Lina M. Moses   +14 more
doaj   +1 more source

Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease

Microbiology Spectrum
Although smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox) global outbreak.
Rajini R. Mudhasani, Joseph W. Golden, Gregory C. Adam, Timothy J. Hartingh, Krishna P. Kota, David Ordonez, Corey R. Quackenbush, Julie P. Tran, Curtis Cline, Janice A. Williams, Xiankun Zeng, David B. Olsen, Linda A. Lieberman, Christopher Boyce, Anthony Ginnetti, J. Matthew Meinig, Rekha G. Panchal, Eric M. Mucker   +17 more
doaj   +1 more source

What has been researched about monkeypox? a bibliometric analysis of an old zoonotic virus causing global concern

New Microbes and New Infections, 2022
Alfonso J. Rodríguez-Morales, Yeimer Ortiz-Martínez, D. Katterine Bonilla-Aldana   +2 more
doaj   +1 more source

Vaccinia Virus in Household Environment during Bovine Vaccinia Outbreak, Brazil

Emerging Infectious Diseases, 2013
Felipe L. Assis, Iara A. Borges, Vaz S. Mesquita, Paulo C. Ferreira, Giliane S. Trindade, Erna G. Kroon, Jonatas S. Abrahão   +6 more
doaj   +1 more source

Monkeypox Virus Surveillance - United States, 2024-2025. [PDF]

MMWR Morb Mortal Wkly Rep
Sandford R, Tuttle A, Aeschleman L, Gigante CM, Davidson W, Wilkins K, Satheshkumar PS, Ajmal A, Hutson CL, Minhaj FS, Hughes CM.   +10 more
europepmc   +1 more source