Results 51 to 60 of about 9,580 (245)

Apparition de lésions proches de la variole bovine chez des bovins en Israël

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996
Les auteurs décrivent deux formes cliniques différentes de variole bovine apparues sporadiquement dans un troupeau laitier et dans un troupeau à viande.
I. Yeruham, A. Nyska, A. Abraham, Radu Algazi   +3 more
doaj   +1 more source

Serological Evidence of Multiple Zoonotic Viral Infections among Wild Rodents in Barbados

Pathogens, 2021
Background: Rodents are reservoirs for several zoonotic pathogens that can cause human infectious diseases, including orthohantaviruses, mammarenaviruses and orthopoxviruses.
Kirk Osmond Douglas, Claire Cayol, Kristian Michael Forbes, Thelma Alafia Samuels, Olli Vapalahti, Tarja Sironen, Marquita Gittens-St. Hilaire   +6 more
doaj   +1 more source

Diagnosis of Imported Monkeypox, Israel, 2018

Emerging Infectious Diseases, 2019
We report a case of monkeypox in a man who returned from Nigeria to Israel in 2018. Virus was detected in pustule swabs by transmission electron microscopy and PCR and confirmed by immunofluorescence assay, tissue culture, and ELISA.
Noam Erez, Hagit Achdout, Elad Milrot, Yuval Schwartz, Yonit Wiener-Well, Nir Paran, Boaz Politi, Hadas Tamir, Tomer Israely, Shay Weiss, Adi Beth-Din, Ohad Shifman, Ofir Israeli, Shmuel Yitzhaki, Shmuel C. Shapira, Sharon Melamed, Eli Schwartz   +16 more
doaj   +1 more source

A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease.

Cell
In response to the 2022 outbreak of mpox driven by unprecedented human-to-human monkeypox virus (MPXV) transmission, we designed BNT166, aiming to create a highly immunogenic, safe, accessible, and scalable next-generation vaccine against MPXV and ...
Adam Zuiani, Charles L. Dulberger, Nilushi S De Silva, M. Marquette, Yu-Jung Lu, G. Palowitch, A. Dokic, Ricardo Sanchez-Velazquez, Katja Schlatterer, Sanjay Sarkar, S. Kar, Bhavna Chawla, A. Galeev, Claudia Lindemann, Daniel A. Rothenberg, Huitian Diao, A. Walls, Theresa A. Addona, Federico J. Mensa, Annette B. Vogel, L. Stuart, R. G. van der Most, John R. Srouji, Ö. Türeci, Richard B. Gaynor, U. Şahin, A. Poran   +26 more
semanticscholar   +1 more source

A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge

Antiviral Research, 2021
Orthopoxviruses such as variola and monkeypox viruses continue to threaten the human population. Monkeypox virus is endemic in central and western Africa and outbreaks have reached as far as the U.S.
S. Parker, J. D’Angelo, R. Buller, D. Smee, J. Lantto, Henriette Nielsen, A. Jensen, M. Prichard, Sarah L. George   +8 more
semanticscholar   +1 more source

Development of ST-246® for Treatment of Poxvirus Infections

Viruses, 2010
ST-246 (Tecovirimat) is a small synthetic antiviral compound being developed to treat pathogenic orthopoxvirus infections of humans. The compound was discovered as part of a high throughput screen designed to identify inhibitors of vaccinia virus-induced
Dennis E. Hruby, Janet M. Leeds, Robert Jordan, Shanthakumar Tyavanagimatt   +3 more
doaj   +1 more source

Monkeypox: Current trends and therapeutic challenges

Annals of Medical Science and Research, 2022
Monkeypox is a viral zoonotic disease that mostly affects tropical rainforest regions of Central and West Africa, with infrequent exportations to other parts of the world.
Pritama Paul, Ritika Singh, Nikhil Era, Sritama Paul, Uttam Kumar Paul   +4 more
doaj   +1 more source

Two noncompeting human neutralizing antibodies targeting MPXV B6 show protective effects against orthopoxvirus infections

Nature Communications
The recent outbreak of mpox epidemic, caused by monkeypox virus (MPXV), poses a new threat to global public health. Here, we initially assessed the preexisting antibody level to the MPXV B6 protein in vaccinia vaccinees born before the end of the ...
Runchu Zhao, Lili Wu, Junqing Sun, Dezhi Liu, Pu Han, Yue Gao, Yi Zhang, Yanli Xu, Xiao Qu, Han Wang, Yan Chai, Zhihai Chen, G. Gao, Qihui Wang   +13 more
semanticscholar   +1 more source

Monkeypox: An alarming global health emergency

APIK Journal of Internal Medicine, 2022
Monkeypox (MPX) virus is an orthopoxvirus that causes human MPX, a viral disease with symptoms indistinguishable to smallpox, which includes fever and rash.
Vasantha Kamath, Srivatsav Sridhar, K Deepthi Reddy   +2 more
doaj   +1 more source

Skin lesions caused by Orthopoxvirus in children

Advances in Dermatology and Allergology, 2020
The global eradication of smallpox and abandonment of mandatory smallpox vaccination has led to an increased proportion of the population who are immunologically naïve to infections caused by Orthopoxviruses (OPV).To present the different courses of OPV infection in children and to highlight the diagnostic difficulties in their differentiation from the
Mazur-Melewska, Katarzyna, Pieczonka-Ruszkowska, Ilona, Szpura, Krystyna, Myszkowska-Torz, Agnieszka, Mania, Anna, Kemnitz, Paweł, Służewski, Wojciech, Figlerowicz, Magdalena   +7 more
openaire   +2 more sources