Results 71 to 80 of about 11,329 (224)

Monkeypox and other orthopoxvirus zoonoses

Veterinary Science Today, 2022
The paper highlights the current knowledge on infection biology, epidemiology and evolution of monkeypox virus (MPXV), cowpox virus (CPXV), buffalopox virus (CPXV), camelpox virus (CMLPV), as well as addresses some factors that modulate dynamics of orthopoxvirus transmission, manifestation of orthopoxvirus infections and their preservation in nature ...
openaire   +2 more sources

The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG, de Quadros, CA, Dowdle, WR, Foege, WH, Henderson, DA, John, TJ, Levine, MM   +6 more
core   +1 more source

Mpox Outbreak in the East Africa Region: Current Status, Containment Measures, Challenges, and Future Direction

Public Health Challenges, Volume 5, Issue 1, March 2026.
The WHO declares the Mpox outbreak a Public Health Emergency of International Concern, with the DRC as the epicenter in the EAC. DRC, Uganda, and Burundi experience extensive transmission; Kenya and Uganda show higher case fatality rates. Containment measures include surveillance, public awareness, infection prevention training, and vaccination (>73 ...
Reuben Sindayiheba, Noel Gahamanyi, Jerome Ndayisenga, Edouard Ntagwabira, Emmanuel Nsengiyumva, Emmanuel Kabalisa, Gashegu Misbah, Isabelle Mukagatare, Leon Mutesa, Claude Mambo Muvunyi   +9 more
wiley   +1 more source

Whole genome sequencing of recombinant viruses obtained from co-infection and superinfection of Vero cells with modified vaccinia virus ankara vectored influenza vaccine and a naturally occurring cowpox virus

Frontiers in Immunology
Modified vaccinia virus Ankara (MVA) has been widely tested in clinical trials as recombinant vector vaccine against infectious diseases and cancers in humans and animals.
Diana Diaz-Cánova, Ugo Moens, Annika Brinkmann, Andreas Nitsche, Malachy Ifeanyi Okeke   +4 more
doaj   +1 more source

Serologic evidence of human orthopoxvirus infections in Sierra Leone

BMC Research Notes, 2011
Background Orthopoxviruses, including variola virus, vaccinia virus, and monkeypox virus, have previously been documented in humans in West Africa, however, no cases of human orthopoxvirus infection have been reported in the region since 1986.
Goba Augustine, Lungay Victor K, Robert Willie, Kanneh Lansana D, Fonnie Richard, Lash RR, Reynolds Mary G, Abel Jason, MacNeil Adam, Moses Lina M, Damon Inger K, Karem Kevin, Bausch Daniel G   +12 more
doaj   +1 more source

Ensemble Docking of FDA‐Approved and Peruvian Phytochemicals Against Monkeypox Virus Telomere‐Binding Protein

ChemistrySelect, Volume 11, Issue 9, 5 March 2026.
ABSTRACT Monkeypox is a reemerging zoonotic disease that has been spreading worldwide. Different approaches are being conducted to find effective treatments for this disease. To accelerate therapeutic discovery, we propose telomere‐binding protein (TBP) as a potential drug target because of its important role during virus maturation.
Edinson Gervacio‐Villarreal, Georcki Ropón‐Palacios, Claudina Sancho, Jhon Pérez‐Silva, Kewin Otazu, Gustavo E. Olivos‐Ramirez, Karolyn Vega‐Chozo, Yaritza L. Ramirez‐Díaz, Manuel E. Chenet‐Zuta, Ivonne Navarro del Aguila, Mario De la Cruz Flores, Cinthia Aguiar, Ihosvany Camps   +12 more
wiley   +1 more source

Severe Scrotal Cellulitis in a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Vera Al Baaklini, Dima Jeha, Alfred Ammoury   +3 more
wiley   +1 more source

An mRNA Vaccine Based on Antigens From Conserved Regions of Monkeypox Virus A35R and M1R With a Dimer‐Like Conformation Confers Protection Against Both Monkeypox Virus and Vaccinia Virus Infections in Mice

MedComm, Volume 7, Issue 2, February 2026.
We developed four candidate mRNA vaccine antigens based on conserved sequences of MPXV A35R and M1R proteins. Our findings demonstrate that the MV2 vaccine possesses favorable immunogenicity and prophylactic potential against MPXV and VACV infections, positioning it as a promising clinical candidate for MPXV prevention.
Cong Tang, Longhai Yuan, Yun Xie, Yun Yang, Yanan Zhou, Junbing Wang, Hao Yang, Rui Peng, Jiali Xu, Wenhai Yu, Qing Huang, Wenqi Quan, Baisheng Li, Youchun Wang, Shuaiyao Lu   +14 more
wiley   +1 more source

Orthopoxvirus infection transmitted by a domestic cat

Journal of the American Academy of Dermatology, 2006
The variola virus was declared eradicated by the World Health Organization in 1980 but human infections by cowpox virus, another member of the genus Orthopoxvirus, are still observed, mainly in European countries. We report a woman who presented with two umbilicated vesicles surrounded by an indurated erythematous edema within cat scratch injuries on ...
Haenssle, Holger Andreas, Kiessling, J., Kempf, Volkhard A. J., Fuchs, Tina, Neumann, C., Emmert, Steffen   +5 more
openaire   +3 more sources

Co-Circulating Monkeypox and Swinepox Viruses, Democratic Republic of the Congo, 2022

Emerging Infectious Diseases
In September 2022, deaths of pigs manifesting pox-like lesions caused by swinepox virus were reported in Tshuapa Province, Democratic Republic of the Congo. Two human mpox cases were found concurrently in the surrounding community.
Thierry Kalonji, Emile Malembi, Jean Paul Matela, Toutou Likafi, Eddy Kinganda-Lusamaki, Emmanuel Hasivirwe Vakaniaki, Nicole A. Hoff, Amuri Aziza, Francisca Muyembe, Joelle Kabamba, Tine Cooreman, Béatrice Nguete, Danae Witte, Ahidjo Ayouba, Nicolas Fernandez-Nuñez, Stijn Roge, Martine Peeters, Sydney Merritt, Steve Ahuka-Mundeke, Eric Delaporte, Elisabeth Pukuta, Joachim Mariën, Eugene Bangwen, Steven Lakin, Charles Lewis, Jeffrey B. Doty, Laurens Liesenborghs, Lisa E. Hensley, Andrea McCollum, Anne W. Rimoin, Jean Jacques Muyembe-Tamfum, Robert Shongo, Didine Kaba, Placide Mbala-Kingebeni   +33 more
doaj   +1 more source