Results 71 to 80 of about 2,721 (157)

Co-Circulating Monkeypox and Swinepox Viruses, Democratic Republic of the Congo, 2022

Emerging Infectious Diseases
In September 2022, deaths of pigs manifesting pox-like lesions caused by swinepox virus were reported in Tshuapa Province, Democratic Republic of the Congo. Two human mpox cases were found concurrently in the surrounding community.
Thierry Kalonji, Emile Malembi, Jean Paul Matela, Toutou Likafi, Eddy Kinganda-Lusamaki, Emmanuel Hasivirwe Vakaniaki, Nicole A. Hoff, Amuri Aziza, Francisca Muyembe, Joelle Kabamba, Tine Cooreman, Béatrice Nguete, Danae Witte, Ahidjo Ayouba, Nicolas Fernandez-Nuñez, Stijn Roge, Martine Peeters, Sydney Merritt, Steve Ahuka-Mundeke, Eric Delaporte, Elisabeth Pukuta, Joachim Mariën, Eugene Bangwen, Steven Lakin, Charles Lewis, Jeffrey B. Doty, Laurens Liesenborghs, Lisa E. Hensley, Andrea McCollum, Anne W. Rimoin, Jean Jacques Muyembe-Tamfum, Robert Shongo, Didine Kaba, Placide Mbala-Kingebeni   +33 more
doaj   +1 more source

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo, Fisseha Assegidew Gebretsadik, Abyou Seyfu Ambaye, Bedilu Linger Endalifer, Teshome Fentik Belachew   +4 more
wiley   +1 more source

5-(Dimethoxymethyl)-2^‘-Deoxyuridine:  A Novel Gem Diether Nucleoside with Anti-Orthopoxvirus Activity

, 2016
To provide potential new leads for the treatment of orthopoxvirus infections, the 5-position of the pyrimidine nucleosides have been modified with a gem diether moiety to yield the following new nucleosides:  5-(dimethoxymethyl)-2‘-deoxyuridine (2b), 5 ...
Xinying Zhang (808783), Earl R. Kern (2497402), Xuesen Fan (808785), Paul F. Torrence (2535820), Kathy A. Keith (2497426), Longhu Zhou (1346283)   +5 more
core   +1 more source

Durability of the Humoral Response to MPXV Infection

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
ABSTRACT Introduction Mpox virus (MPXV) re‐emerged in endemic countries in recent decades, resulting in large outbreaks in central and western Africa and a worldwide epidemic of clade IIb MPXV starting in 2022. Mpox cases in vaccinated persons, and a few documented reinfections, have raised questions about the durability of MPXV humoral immunity ...
Tara N. Palmore
wiley   +1 more source

From actually toxic to highly specific – novel drugs against poxviruses [PDF]

, 2007
The potential use of variola virus, the causative agent of smallpox, as a bioweapon and the endemic presence of monkeypox virus in Africa demonstrate the need for better therapies for orthopoxvirus infections. Chemotherapeutic approaches to control viral
Schnierle Barbara, Sliva Katja, Sliva, Katja, Schnierle, Barbara, Barbara Schnierle, Katja Sliva   +5 more
core   +1 more source

Orthopoxvirus infection among wildlife in Zambia

Journal of General Virology, 2015
(Uploaded by Plazi for the Bat Literature Project) Human monkeypox is a viral zoonosis caused by monkeypox virus, an orthopoxvirus (OPXV). The majority of human monkeypox cases have been reported in moist forested regions in West and Central Africa, particularly in the Democratic Republic of the Congo (DRC).
Orba, Yasuko, Sasaki, Michihito, Yamaguchi, Hiroki, Ishii, Akihiro, Thomas, Yuka, Ogawa, Hirohito, Hang'ombe, Bernard M., Mweene, Aaron S., Morikawa, Shigeru, Saijo, Masayuki, Sawa, Hirofumi   +10 more
openaire   +5 more sources

Discovery and Structural Characterization of a Highly Protective Neutralizing Antibody Targeting the Mpox Virus A35R Protein

MedComm, Volume 7, Issue 7, July 2026.
High‐affinity monoclonal antibodies (mAbs) targeting the MPXV EEV protein A35R were rapidly isolated using mRNA‐LNP vaccination and the Beacon single‐cell sorting Optofluidic platform, followed by functional profiling. One mAb, 17H1, potently neutralized authentic MPXV and conferred complete protection in vivo.
Shimeng Bai, Shuo Song, Xin Wang, Yuxin Xiao, Yun Long, Fenfang Wu, Fuxiang Wang, Zhongyi Fan, Jianqing Xu, Maozhou He, Hongzhou Lu   +10 more
wiley   +1 more source

Report of meeting of the Study Group on Orthopoxvirus Research, Atlanta, 26-28 June 1979 [PDF]

In December 1978 the Global Commission for the Certification of Smallpox Eradication considered all aspects of the programme. One of the objectives of the Global Commission was "to recommend research activities regarding: possible animal reservoirs of ...

core  

Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil

Domestic animals can share viral pathogens with humans, acting mainly as a bridge host. The Orthopoxvirus genus hosts important zoonotic species that have emerged in urban areas worldwide.
Trindade, Giliane de Souza, Débora de Meneses, Reis, Alexandre Barbosa, Karolina L. Dias, Wendel Coura-Vital, Thallyta M. Vieira, Vieira, Thallyta Maria, Dutra, Ana Gabriella Stoffella, Iago José da S. Domingos, Ana G. Stoffella-Dutra, Iara M. de Almeida, Giliane de S. Trindade, Ribeiro, Gabriela Pereira, Almeida, Iara Monteiro de, Domingos, Iago José da Silva, Blaso, Vicenzo Soares, Vital, Wendel Coura, Meneses, Débora de, Gabriela P. Ribeiro, Vicenzo S. Blaso, Alexandre B. Reis, Dias, Karolina L.   +21 more
core   +1 more source

Presence of neutralizing antibodies to Orthopoxvirus in Capybaras (Hydrochoerus hydrochaeris) in Brazil

Journal of Infection in Developing Countries, 2014
Cantagalo virus is a strain of vaccinia virus (genus Orthopoxvirus) and the etiological agent of an important vesicopustular disease that affects dairy cows and milkers in Brazil.
André Victor Barbosa, Maria Luiza G Medaglia, Herbert S Soares, Jociane C Quixabeira-Santos, Solange M Gennari, Clarissa R Damaso   +5 more
doaj   +1 more source