Results 91 to 100 of about 11,329 (224)
Monkeypox has garnered significant attention following its emergence in multiple countries and its designation as a global health emergency in 2022. There is a notable deficiency in clinical and experimental data regarding pregnancy outcomes following monkeypox infection.
Jingyi Wu +3 more
wiley +1 more source
Insights into poxviruses: virology and vaccines
Due to the successful eradication of smallpox worldwide and the cessation of smallpox vaccination campaign in 1980, the human population seems to be more susceptible to poxvirus infection.
Adriana Manuka +5 more
doaj +1 more source
Novel Orthopoxvirus and Lethal Disease in Cat, Italy
We report detection and full-genome characterization of a novel orthopoxvirus (OPXV) responsible for a fatal infection in a cat. The virus induced skin lesions histologically characterized by leukocyte infiltration and eosinophilic cytoplasmic inclusions.
Gianvito Lanave +10 more
doaj +1 more source
The current research examines the stability characteristics and practical uses of a delayed monkeypox outbreak model. The model divides the human population into four compartments: susceptible, exposed, infectious, and recovered individuals. A discrete time delay is incorporated to represent the incubation period and public‐health response.
Ali Raza +5 more
wiley +1 more source
From the animal house to the field : are there consistent individual differences in immunological profile in wild populations of field voles (Microtus agrestis)? [PDF]
Inbred mouse strains, living in simple laboratory environments far removed from nature, have been shown to vary consistently in their immune response.
A Gelman +47 more
core +6 more sources
Conservation and Variation in Orthopoxvirus Genome Structure
Orthopoxvirus DNA from representative strains of rabbitpox, vaccinia, monkeypox, variola, cowpox and ectromelia viruses was analysed by cleavage with restriction endonucleases HindIII, XhoI or SmaI. Genome mol. wt. vary from about 120 x 10(6) for rabbitpox to about 145 x 10(6) for cowpox.
M, Mackett, L C, Archard
openaire +2 more sources
Experimental intranasal infection of marmosets (Callithrix jacchus) with calpox virus results in fatal disease. Route and dose used for viral inoculation of the test animals mimics the natural transmission of smallpox, thus representing a suitable model ...
Anne Schmitt +7 more
doaj +1 more source
Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex [PDF]
VACV gene C16L encodes a 37-kDa protein that is highly conserved in orthopoxviruses and functions as an immunomodulator. Intranasal infection of mice with a virus lacking C16L (vΔC16) induced less weight loss, fewer signs of illness and increased ...
Peters, Nicholas Edward +1 more
core +1 more source
Cowpox with Severe Generalized Eruption, Finland
Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies.
Paula M. Pelkonen +7 more
doaj +1 more source
Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily [PDF]
Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any ...
Alcami +40 more
core +3 more sources

