Results 181 to 190 of about 11,329 (224)
Some of the next articles are maybe not open access.
2004
Biologic and antigenic properties are often useful for identifying and differentiating orthopoxviruses (OPV). However, polymerase chain reaction (PCR) amplification, with either restriction cleavage or sequencing of amplicons, has been gaining credibility as a more rapid, specific, sensitive, and often cost-saving technique for research and diagnostic ...
Hermann, Meyer +2 more
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Biologic and antigenic properties are often useful for identifying and differentiating orthopoxviruses (OPV). However, polymerase chain reaction (PCR) amplification, with either restriction cleavage or sequencing of amplicons, has been gaining credibility as a more rapid, specific, sensitive, and often cost-saving technique for research and diagnostic ...
Hermann, Meyer +2 more
openaire +2 more sources
1990
Genetic analysis of orthopoxviruses has contributed substantially to our understanding of the functional organization of the poxvirus genome, and individual mutants provide invaluable tools for future studies of poxvirus biology. Deletion and transposition mutants, localized primarily in the termini of the genome, may be particularly useful for ...
R C, Condit, E G, Niles
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Genetic analysis of orthopoxviruses has contributed substantially to our understanding of the functional organization of the poxvirus genome, and individual mutants provide invaluable tools for future studies of poxvirus biology. Deletion and transposition mutants, localized primarily in the termini of the genome, may be particularly useful for ...
R C, Condit, E G, Niles
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The preparation of orthopoxvirus DNA
Journal of Virological Methods, 1981Abstract A method is presented for the preparation of cross-linked, intact orthopoxvirus DNA from viral cores extracted from virus-infected cell cultures.
J, Esposito, R, Condit, J, Obijeski
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Orthopoxvirus infection among wildlife in Zambia
Journal of General Virology, 2015(Uploaded by Plazi for the Bat Literature Project) Human monkeypox is a viral zoonosis caused by monkeypox virus, an orthopoxvirus (OPXV). The majority of human monkeypox cases have been reported in moist forested regions in West and Central Africa, particularly in the Democratic Republic of the Congo (DRC).
Orba, Yasuko +10 more
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Animal Models of Orthopoxvirus Infection
Veterinary Pathology, 2010Smallpox was one of the most devastating diseases known to humanity. Although smallpox was eradicated through a historically successful vaccination campaign, there is concern in the global community that either Variola virus (VARV), the causative agent of smallpox, or another species of Orthopoxvirus could be used as agents of bioterrorism. Therefore,
J L, Chapman +3 more
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Genus Orthopoxvirus: Monkeypox virus
2007Monkeypox virus is an orthopoxvirus that is genetically distinct from other members of the genus, including Variola virus, Vaccinia virus, Ectromelia virus, Camelpox virus, and Cowpox virus. It was first identified as the cause of a pox-like illness in captive monkeys in 1958.
Sandra Essbauer, Hermann Meyer
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Genus Orthopoxvirus: Cowpox virus
2007Cowpox virus (CPXV) is distinguished from other orthopoxvirus (OPV) species by producing cytoplasmic A-type inclusion bodies and flattened pocks with a hemorrhagic center on the chorioallantoic membrane. CPXV is endemic to Western Eurasia and naturally infects a broad range of host species including domestic animals, and zoo animals, as well as humans.
Sandra Essbauer, Hermann Meyer
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Smallpox and Other Orthopoxvirus Diseases
VacciTUTOR, 2022Smallpox was a severe disease causing substantial mortality among populations over several thousand years. It is caused by an orthopoxvirus, the variola (= smallpox) virus. Smallpox is a febrile disease with a maculo-, papulo-, vesicular and finally pustular rash, the typical pox lesions, numerous complications and a fatality rate of approximately 30%.
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Pharmacological Review on Orthopoxvirus
Research Journal of Pharmacology and PharmacodynamicsMonkeypox is an emerging viral zoonotic disease caused by the monkeypox virus, which is particularly significant as it is endemic to Central and Western Africa. This disease is rare and manifests with a rash resembling that of smallpox. However, its transmission between individuals beyond close contact is limited, and the case fatality rates for ...
P. Devi Guna Sireesha +4 more
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The mechanism of cytoplasmic orthopoxvirus DNA replication
Cell, 1981Orthopoxvirus DNA replication occurs in the cytoplasm of infected cells within discrete foci designated as virosomes. We show that newly synthesized rabbit poxvirus (RPV) virosomal DNA consists predominantly of concatamers wherein unit length molecules are joined by fusion of two left (LL) or right (RR) ends, resulting in genomes aligned in alternating
R W, Moyer, R L, Graves
exaly +3 more sources