Results 31 to 40 of about 9,930 (245)
The French Armed Forces Virology Unit: A Chronological Record of Ongoing Research on Orthopoxvirus
Since the official declaration of smallpox eradication in 1980, the general population vaccination has ceased worldwide. Therefore, people under 40 year old are generally not vaccinated against smallpox and have no cross protection against orthopoxvirus ...
Déborah Delaune+4 more
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The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has highlighted the critical importance of timely virus detection and robust public health surveillance in assessing outbreaks and their impact.
Sumit Aggarwal+5 more
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Vaccinia Virus Infection in Monkeys, Brazilian Amazon
To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples.
Jônatas S. Abrahão+13 more
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The worldwide outbreak of the monkeypox virus (MPXV) has become a “Public Health Emergency of International Concern” (PHEIC). Severe monkeypox virus infection can be fatal, however, effective therapeutic methods are yet to be developed.
Mengjun Li+21 more
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Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections [PDF]
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health. The current licensed live vaccinia virus-based smallpox vaccine is extremely effective as a prophylactic vaccine to prevent orthopoxvirus infections, but because of safety issues, it is no ...
Stuart N. Isaacs, Yuhong Xiao
openaire +4 more sources
Monkeypox, caused by a zoonotic orthopoxvirus, is endemic in Central and West Africa. Monkeypox has been sporadically reported in the Republic of the Congo. During March 22–April 5, 2017, we investigated 43 suspected human monkeypox cases. We interviewed
Reena H. Doshi+22 more
doaj +1 more source
Orthopoxvirus Seroprevalence and Infection Susceptibility in France, Bolivia, Laos, and Mali
To determine a demographic overview of orthopoxvirus seroprevalence, we tested blood samples collected during 2003–2019 from France (n = 4,876), Bolivia (n = 601), Laos (n = 657), and Mali (n = 255) for neutralizing antibodies against vaccinia virus. In
Léa Luciani+11 more
doaj +1 more source
Development of ST-246® for Treatment of Poxvirus Infections
ST-246 (Tecovirimat) is a small synthetic antiviral compound being developed to treat pathogenic orthopoxvirus infections of humans. The compound was discovered as part of a high throughput screen designed to identify inhibitors of vaccinia virus-induced
Dennis E. Hruby+3 more
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Cowpox after a cat scratch – case report from Poland
Cowpox in humans is a rare zoonotic disease; its recognition is therefore problematic due to the lack of clinical experience. The differential diagnosis includes other poxvirus infections and also infections with herpesviruses or selected bacteria.
Karolina Świtaj+3 more
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La variole du dromadaire chez le jeune au Maroc. Isolement et identification du virus. Mise au point du vaccin et application à la prophylaxie [PDF]
La variole cameline est une pathologie majeure de l'espèce. Le virus (Orthopoxvirus cameli) a pu être isolé au Maroc. La souche isolée après huit passages sur cellules Vero a été dénommée T8.
El Harrak, Mehdi, Loutfi, C.
core +2 more sources