Results 31 to 40 of about 9,930 (245)

The French Armed Forces Virology Unit: A Chronological Record of Ongoing Research on Orthopoxvirus

open access: yesViruses, 2017
Since the official declaration of smallpox eradication in 1980, the general population vaccination has ceased worldwide. Therefore, people under 40 year old are generally not vaccinated against smallpox and have no cross protection against orthopoxvirus ...
Déborah Delaune   +4 more
doaj   +1 more source

Mapping the Landscape of Health Research Priorities for Effective Pandemic Preparedness in Human Mpox Virus Disease

open access: yesPathogens, 2023
The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has highlighted the critical importance of timely virus detection and robust public health surveillance in assessing outbreaks and their impact.
Sumit Aggarwal   +5 more
doaj   +1 more source

Vaccinia Virus Infection in Monkeys, Brazilian Amazon

open access: yesEmerging Infectious Diseases, 2010
To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples.
Jônatas S. Abrahão   +13 more
doaj   +1 more source

Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus

open access: yesEmerging Microbes and Infections, 2023
The worldwide outbreak of the monkeypox virus (MPXV) has become a “Public Health Emergency of International Concern” (PHEIC). Severe monkeypox virus infection can be fatal, however, effective therapeutic methods are yet to be developed.
Mengjun Li   +21 more
doaj   +1 more source

Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections [PDF]

open access: yesViruses, 2010
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health. The current licensed live vaccinia virus-based smallpox vaccine is extremely effective as a prophylactic vaccine to prevent orthopoxvirus infections, but because of safety issues, it is no ...
Stuart N. Isaacs, Yuhong Xiao
openaire   +4 more sources

Epidemiologic and Ecologic Investigations of Monkeypox, Likouala Department, Republic of the Congo, 2017

open access: yesEmerging Infectious Diseases, 2019
Monkeypox, caused by a zoonotic orthopoxvirus, is endemic in Central and West Africa. Monkeypox has been sporadically reported in the Republic of the Congo. During March 22–April 5, 2017, we investigated 43 suspected human monkeypox cases. We interviewed
Reena H. Doshi   +22 more
doaj   +1 more source

Orthopoxvirus Seroprevalence and Infection Susceptibility in France, Bolivia, Laos, and Mali

open access: yesEmerging Infectious Diseases, 2022
To determine a demographic overview of orthopoxvirus seroprevalence, we tested blood samples collected during 2003–2019 from France (n = 4,876), Bolivia (n = 601), Laos (n = 657), and Mali (n = 255) for neutralizing antibodies against vaccinia virus. In
Léa Luciani   +11 more
doaj   +1 more source

Development of ST-246® for Treatment of Poxvirus Infections

open access: yesViruses, 2010
ST-246 (Tecovirimat) is a small synthetic antiviral compound being developed to treat pathogenic orthopoxvirus infections of humans. The compound was discovered as part of a high throughput screen designed to identify inhibitors of vaccinia virus-induced
Dennis E. Hruby   +3 more
doaj   +1 more source

Cowpox after a cat scratch – case report from Poland

open access: yesAnnals of Agricultural and Environmental Medicine, 2015
Cowpox in humans is a rare zoonotic disease; its recognition is therefore problematic due to the lack of clinical experience. The differential diagnosis includes other poxvirus infections and also infections with herpesviruses or selected bacteria.
Karolina Świtaj   +3 more
doaj   +1 more source

La variole du dromadaire chez le jeune au Maroc. Isolement et identification du virus. Mise au point du vaccin et application à la prophylaxie [PDF]

open access: yes, 2000
La variole cameline est une pathologie majeure de l'espèce. Le virus (Orthopoxvirus cameli) a pu être isolé au Maroc. La souche isolée après huit passages sur cellules Vero a été dénommée T8.
El Harrak, Mehdi, Loutfi, C.
core   +2 more sources

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