Results 31 to 40 of about 7,538 (211)
Viral genomic features predictorthopoxvirusreservoir hosts
Communications Biology, 2023 AbstractOrthopoxviruses (OPVs), including the causative agents of smallpox and mpox have led to devastating outbreaks in human populations worldwide. However, the discontinuation of smallpox vaccination, which also provides cross-protection against related OPVs, has diminished global immunity to OPVs more broadly.
Katie K. Tseng +6 more
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Development of ST-246® for Treatment of Poxvirus Infections
Viruses, 2010 ST-246 (Tecovirimat) is a small synthetic antiviral compound being developed to treat pathogenic orthopoxvirus infections of humans. The compound was discovered as part of a high throughput screen designed to identify inhibitors of vaccinia virus-induced
Dennis E. Hruby +3 more
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Rapid and high-throughput pan-Orthopoxvirus detection and identification using PCR and mass spectrometry. [PDF]
PLoS ONE, 2009 The genus Orthopoxvirus contains several species of related viruses, including the causative agent of smallpox (Variola virus). In addition to smallpox, several other members of the genus are capable of causing human infection, including monkeypox ...
Mark W Eshoo +16 more
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Viruses, 2022 Monkeypox disease (MPX) is currently considered a global threat after COVID-19. European Medicines Agency (EMA) approved Tecovirimat in capsule dosage form (200 mg) as the first treatment for MPX in January 2022.
Mazen Almehmadi +11 more
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Skin lesions caused by Orthopoxvirus in children
Advances in Dermatology and Allergology, 2020 The global eradication of smallpox and abandonment of mandatory smallpox vaccination has led to an increased proportion of the population who are immunologically naïve to infections caused by Orthopoxviruses (OPV).To present the different courses of OPV infection in children and to highlight the diagnostic difficulties in their differentiation from the
Mazur-Melewska, Katarzyna +7 more
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Monkeypox: Current trends and therapeutic challenges
Annals of Medical Science and Research, 2022 Monkeypox is a viral zoonotic disease that mostly affects tropical rainforest regions of Central and West Africa, with infrequent exportations to other parts of the world.
Pritama Paul +4 more
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Monkeypox: An alarming global health emergency
APIK Journal of Internal Medicine, 2022 Monkeypox (MPX) virus is an orthopoxvirus that causes human MPX, a viral disease with symptoms indistinguishable to smallpox, which includes fever and rash.
Vasantha Kamath +2 more
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Microbiology Spectrum, 2022 Monkeypox virus (MPXV) is a human pathogenic virus that belongs to the genus Orthopoxvirus. In 2022, MPXV caused an unprecedented number of infections in many countries.
Junxia Feng +18 more
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Orthopoxvirus DNA in Eurasian Lynx, Sweden
Emerging Infectious Diseases, 2011 Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ranging Eurasian lynx (Lynx lynx) from Sweden. Thymidine
Tryland, Morten +5 more
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Cowpox after a cat scratch – case report from Poland
Annals of Agricultural and Environmental Medicine, 2015 Cowpox in humans is a rare zoonotic disease; its recognition is therefore problematic due to the lack of clinical experience. The differential diagnosis includes other poxvirus infections and also infections with herpesviruses or selected bacteria.
Karolina Świtaj +3 more
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