Results 211 to 220 of about 48,813 (224)
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Cell Calcium, 1991
Receptor-activated cytoplasmic calcium (Ca2+) oscillations have been investigated in single pancreatic acinar cells by microfluorimetry (Fura-2 as indicator). At submaximal concentrations of the agonists acetylcholine (ACh) and cholecystokinin octapeptide (CCK-8), both give rise to oscillatory changes in the cytosolic free calcium concentration ([Ca2 ...
David I. Yule +2 more
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Receptor-activated cytoplasmic calcium (Ca2+) oscillations have been investigated in single pancreatic acinar cells by microfluorimetry (Fura-2 as indicator). At submaximal concentrations of the agonists acetylcholine (ACh) and cholecystokinin octapeptide (CCK-8), both give rise to oscillatory changes in the cytosolic free calcium concentration ([Ca2 ...
David I. Yule +2 more
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Modelling of simple and complex calcium oscillations
European Journal of Biochemistry, 2002This review provides a comparative overview of recent developments in the modelling of cellular calcium oscillations. A large variety of mathematical models have been developed for this wide‐spread phenomenon in intra‐ and intercellular signalling. From these, a general model is extracted that involves six types of concentration variables: inositol 1,4,
Marko Marhl +3 more
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1990
Isopeptides of the newly discovered peptide family, endothelins (ET), caused a concentration-dependent increase in intracellular free [Ca2+] ([Ca2+]i) in human glomerular mesangial cells. ET isopeptides and sarafotoxin S6b caused transient and sustained [Ca2+]i waveforms which resulted from mobilization of intracellular Ca2+ stores and from Ca2+ influx
Michael S. Simonson +2 more
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Isopeptides of the newly discovered peptide family, endothelins (ET), caused a concentration-dependent increase in intracellular free [Ca2+] ([Ca2+]i) in human glomerular mesangial cells. ET isopeptides and sarafotoxin S6b caused transient and sustained [Ca2+]i waveforms which resulted from mobilization of intracellular Ca2+ stores and from Ca2+ influx
Michael S. Simonson +2 more
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Cell Calcium, 1991
Receptor-activated cytoplasmic Ca2+ oscillations have been investigated using both single cell microfluorometry and voltage-clamp recording of Ca(2+)-dependent Cl- current in single internally perfused acinar cells. In these cells there is direct experimental evidence showing that the ACh-evoked [Ca2+]i fluctuations are due to an inositol trisphosphate-
Carl C.H. Petersen +5 more
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Receptor-activated cytoplasmic Ca2+ oscillations have been investigated using both single cell microfluorometry and voltage-clamp recording of Ca(2+)-dependent Cl- current in single internally perfused acinar cells. In these cells there is direct experimental evidence showing that the ACh-evoked [Ca2+]i fluctuations are due to an inositol trisphosphate-
Carl C.H. Petersen +5 more
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Abstract A03: SCFCyclin F connects AKT signaling to the core cell cycle oscillator
Molecular Cancer Research, 2016Abstract Cell proliferation is governed by the presence of growth factors, and in their absence normal cells cease to progress through the cell cycle. The waves of Cyclin Dependent Kinase (CDK) activity constituting the core of the cell cycle oscillator are driven by cyclin synthesis and its subsequent destruction by the Anaphase ...
Christine A. Mills +5 more
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Cell Calcium, 2006
Human bone marrow-derived mesenchymal stem cells (hMSCs) have the potential to differentiate into several types of cells. Calcium ions (Ca(2+)) play an important role in the differentiation and proliferation of hMSCs. We have demonstrated that spontaneous [Ca(2+)](i) oscillations occur without agonist stimulation in hMSCs.
Fumio Yoshikawa +10 more
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Human bone marrow-derived mesenchymal stem cells (hMSCs) have the potential to differentiate into several types of cells. Calcium ions (Ca(2+)) play an important role in the differentiation and proliferation of hMSCs. We have demonstrated that spontaneous [Ca(2+)](i) oscillations occur without agonist stimulation in hMSCs.
Fumio Yoshikawa +10 more
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Oscillating two-dimensional Ca2+ waves in cell networks with bidirectional paracrine signaling
Waves in Random and Complex Media, 2019Nonlinear excitations of Ca2+ waves are investigated in a two-dimensional cell network with bidirectional paracrine signaling, both in the longitudinal and transversal directions.
Armand Sylvin Etémé +5 more
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Journal of Basic and Clinical Physiology and Pharmacology, 1999
We studied effects of heat acclimation (HA) and acute heat stress (HS) on Ca2+ signal oscillations following supramaximal carbamyl-choline (CCh) stimulation, using HSY cell line as a model. In the control cells, oscillations decreased their amplitude with time.
Arie Moran +2 more
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We studied effects of heat acclimation (HA) and acute heat stress (HS) on Ca2+ signal oscillations following supramaximal carbamyl-choline (CCh) stimulation, using HSY cell line as a model. In the control cells, oscillations decreased their amplitude with time.
Arie Moran +2 more
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Journal of Neurophysiology, 2006
Fast synaptic transmission between olfactory receptor neurons and mitral cells (MCs) is mediated through AMPA and NMDA ionotropic glutamate receptors. MCs also express high levels of metabotropic glutamate receptor 1 (mGluR1) whose functional significance is less understood.
Thomas Knöpfel, Q. Yuan
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Fast synaptic transmission between olfactory receptor neurons and mitral cells (MCs) is mediated through AMPA and NMDA ionotropic glutamate receptors. MCs also express high levels of metabotropic glutamate receptor 1 (mGluR1) whose functional significance is less understood.
Thomas Knöpfel, Q. Yuan
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Regulation of Cell Division Cycles by Circadian Oscillators: Signal Transduction Between Clocks
1997An important consideration for maximizing the results of radio- and chemotherapy of mammalian cancers is that of host tolerance. It is unfortunate that in most of the earlier cancer work there is little mention of the role of rhythmic variations (particularly circadian periodicities) in the susceptibility of the whole organism to the toxicity of the ...
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