Results 281 to 290 of about 1,311,722 (333)
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Journal of Cellular Physiology, 2021
AbstractA persistent basal tone in the internal anal sphincter (IAS) is essential for keeping the anal canal closed and fecal continence; its inhibition via the rectoanal inhibitory reflex (RAIR) is required for successful defecation. However, cellular signals underlying the IAS basal tone remain enigmatic.
Ping Lu +7 more
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AbstractA persistent basal tone in the internal anal sphincter (IAS) is essential for keeping the anal canal closed and fecal continence; its inhibition via the rectoanal inhibitory reflex (RAIR) is required for successful defecation. However, cellular signals underlying the IAS basal tone remain enigmatic.
Ping Lu +7 more
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Cell Calcium, 1991
Receptor-activated cytoplasmic calcium (Ca2+) oscillations have been investigated in single pancreatic acinar cells by microfluorimetry (Fura-2 as indicator). At submaximal concentrations of the agonists acetylcholine (ACh) and cholecystokinin octapeptide (CCK-8), both give rise to oscillatory changes in the cytosolic free calcium concentration ([Ca2 ...
D I, Yule, A M, Lawrie, D V, Gallacher
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Receptor-activated cytoplasmic calcium (Ca2+) oscillations have been investigated in single pancreatic acinar cells by microfluorimetry (Fura-2 as indicator). At submaximal concentrations of the agonists acetylcholine (ACh) and cholecystokinin octapeptide (CCK-8), both give rise to oscillatory changes in the cytosolic free calcium concentration ([Ca2 ...
D I, Yule, A M, Lawrie, D V, Gallacher
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The European Physical Journal B, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yi, Q. Z. +3 more
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zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yi, Q. Z. +3 more
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Abstract A03: SCFCyclin F connects AKT signaling to the core cell cycle oscillator
Molecular Cancer Research, 2016Abstract Cell proliferation is governed by the presence of growth factors, and in their absence normal cells cease to progress through the cell cycle. The waves of Cyclin Dependent Kinase (CDK) activity constituting the core of the cell cycle oscillator are driven by cyclin synthesis and its subsequent destruction by the Anaphase ...
Michael J. Emanuele +5 more
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Journal of Cell Science, 1978
ABSTRACT Cells of Dictyostelium discoideum known to release cyclic AMP (cAMP) rhythmically in the form of pulses, change with the same period of about 8 min the pH of their medium. The pH is used here as an indicator to investigate the effect of externally added cAMP pulses on the oscillations.
D, Malchow, V, Nanjundiah, G, Gerisch
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ABSTRACT Cells of Dictyostelium discoideum known to release cyclic AMP (cAMP) rhythmically in the form of pulses, change with the same period of about 8 min the pH of their medium. The pH is used here as an indicator to investigate the effect of externally added cAMP pulses on the oscillations.
D, Malchow, V, Nanjundiah, G, Gerisch
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1990
Isopeptides of the newly discovered peptide family, endothelins (ET), caused a concentration-dependent increase in intracellular free [Ca2+] ([Ca2+]i) in human glomerular mesangial cells. ET isopeptides and sarafotoxin S6b caused transient and sustained [Ca2+]i waveforms which resulted from mobilization of intracellular Ca2+ stores and from Ca2+ influx
M S, Simonson, T, Osanai, M J, Dunn
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Isopeptides of the newly discovered peptide family, endothelins (ET), caused a concentration-dependent increase in intracellular free [Ca2+] ([Ca2+]i) in human glomerular mesangial cells. ET isopeptides and sarafotoxin S6b caused transient and sustained [Ca2+]i waveforms which resulted from mobilization of intracellular Ca2+ stores and from Ca2+ influx
M S, Simonson, T, Osanai, M J, Dunn
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On the effect of circadian oscillations on biochemical cell signaling by NF−κB
Journal of Theoretical Biology, 2013We report the results of a numerical investigation of a mathematical model for NF-κB oscillations, described by a set of ordinary nonlinear differential equations, when perturbed by a circadian oscillation. The main result is that a circadian rhythm, even when it represents a weak perturbation, enhances the signaling capabilities of NF-κB oscillations.
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Cell Calcium, 2006
Human bone marrow-derived mesenchymal stem cells (hMSCs) have the potential to differentiate into several types of cells. Calcium ions (Ca(2+)) play an important role in the differentiation and proliferation of hMSCs. We have demonstrated that spontaneous [Ca(2+)](i) oscillations occur without agonist stimulation in hMSCs.
Seiko, Kawano +9 more
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Human bone marrow-derived mesenchymal stem cells (hMSCs) have the potential to differentiate into several types of cells. Calcium ions (Ca(2+)) play an important role in the differentiation and proliferation of hMSCs. We have demonstrated that spontaneous [Ca(2+)](i) oscillations occur without agonist stimulation in hMSCs.
Seiko, Kawano +9 more
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Cell Calcium, 1991
Receptor-activated cytoplasmic Ca2+ oscillations have been investigated using both single cell microfluorometry and voltage-clamp recording of Ca(2+)-dependent Cl- current in single internally perfused acinar cells. In these cells there is direct experimental evidence showing that the ACh-evoked [Ca2+]i fluctuations are due to an inositol trisphosphate-
O H, Petersen +5 more
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Receptor-activated cytoplasmic Ca2+ oscillations have been investigated using both single cell microfluorometry and voltage-clamp recording of Ca(2+)-dependent Cl- current in single internally perfused acinar cells. In these cells there is direct experimental evidence showing that the ACh-evoked [Ca2+]i fluctuations are due to an inositol trisphosphate-
O H, Petersen +5 more
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Experientia, 1992
We investigate how the introduction of cells oscillating periodically affects the behaviour of a suspension of Dictyostelium discoideum amoebae undergoing chaotic oscillations of cyclic AMP. The analysis of a model indicates that a tiny proportion of periodic cells suffices to transform chaos into periodic oscillations in such suspensions.
Li, Yue-Xian +4 more
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We investigate how the introduction of cells oscillating periodically affects the behaviour of a suspension of Dictyostelium discoideum amoebae undergoing chaotic oscillations of cyclic AMP. The analysis of a model indicates that a tiny proportion of periodic cells suffices to transform chaos into periodic oscillations in such suspensions.
Li, Yue-Xian +4 more
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