Results 71 to 80 of about 34,354 (193)

Plasma concentrations of oseltamivir and oseltamivir carboxylate in critically ill children on extracorporeal membrane oxygenation support. [PDF]

PLoS ONE, 2010
INTRODUCTION: To evaluate the effect of extracorporeal membrane oxygenation (ECMO) support on pharmacokinetics of oseltamivir and oseltamivir carboxylate (OC) in children.
Enno D Wildschut, Matthijs de Hoog, Maurice J Ahsman, Dick Tibboel, Albert D M E Osterhaus, Pieter L A Fraaij   +5 more
doaj   +1 more source

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade, Rhiannon Potter, Alex Inskip, Jane Nesworthy, Kirsti Brock, Gill Norman   +5 more
wiley   +1 more source

Aggregation of Single Nucleotide Polymorphisms in a Human H5N1 Clade 2.2 Hemagglutinin [PDF]

, 2007
The evolution of H5N1 has attracted significant interest 1-4 due to linkages with avian 5,6 and human infections 7,8. The basic tenets of influenza genetics 9 attribute genetic drift to replication errors caused by a polymerase complex that lacks a ...
Abdelattar Arafa, Ahmed E. Nayel, Ahmed S. Abdelghani, Bruce R. Boynton, Ehab A. Ayoub, Emad M. Labib, Gregory A. Raczniak, Hala M. Esmat, Henry L. Niman, Jeffery Tjaden, Kenneth C. Earhart, Magdi D. Saad, Marshall R. Monteville, Mensah Agyen-Frempong, Mona M. Aly, Moustafa M. Mansour, Nasr El-Sayed, William K. Ampofo   +17 more
core   +6 more sources

Influenza and the implications of a pandemic for Malta [PDF]

, 2005
An influenza pandemic is inevitable and recent reports from Southeast Asia on avian influenza viruses infecting humans have served to fuel worries that a new pandemic is near.
Farrugia, Ryan, Melillo Fenech, Tanya, Spiteri, Gianfranco   +2 more
core  

Neuraminidase inhibitors for influenza: a systematic review and meta-analysis of regulatory and mortality data

Health Technology Assessment, 2016
Background: Neuraminidase inhibitors (NIs) are stockpiled and recommended by public health agencies for treating and preventing seasonal and pandemic influenza. They are used clinically worldwide.
Carl J Heneghan, Igho Onakpoya, Mark A Jones, Peter Doshi, Chris B Del Mar, Rokuro Hama, Matthew J Thompson, Elizabeth A Spencer, Kamal R Mahtani, David Nunan, Jeremy Howick, Tom Jefferson   +11 more
doaj   +1 more source

Decreased Hospital Length of Stay With Early Administration of Oseltamivir in Patients Hospitalized With Influenza

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2020
Objective: To evaluate the effects of timely oseltamivir administration in patients hospitalized with seasonal influenza. Patients and Methods: We performed a single-center retrospective cohort study for hospitalized patients who tested positive for ...
Lin Dou, MD, Dan Reynolds, MD, Lindsey Wallace, MS, PA-C, John O’Horo, MD, MPH, Rahul Kashyap, MBBS, Ognjen Gajic, MD, Hemang Yadav, MBBS   +6 more
doaj   +1 more source

Application of Metagenomic Next‐Generation Sequencing in the Diagnosis of Pneumonia in Patients With Cancer

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background With the development of new sequencing technologies, metagenomic next‐generation sequencing (mNGS) has become a diagnostic tool for respiratory tract infections. Patients with cancer may develop pneumonia caused by infections or antitumor therapy.
Rong Qin, Chao Wang, Minghua Cong, Le Tian, Ning Li   +4 more
wiley   +1 more source

Rapid Multiplex Testing for Upper Respiratory Pathogens in the Emergency Department: A Randomized Controlled Trial. [PDF]

, 2019
Background:Acute upper respiratory tract infections are a common cause of emergency department (ED) visits and often result in unnecessary antibiotic treatment.
Bang, Heejung, Hon, Simson, May, Larissa, Mooso, Benjamin, Polage, Christopher, Poltavskiy, Eduard, Tatro, Grant   +6 more
core  

Effectiveness of four types of neuraminidase inhibitors approved in Japan for the treatment of influenza.

PLoS ONE, 2019
BACKGROUND:Neuraminidase inhibitors (NAIs) effectively treat influenza. The clinical effectiveness of four NAIs (oseltamivir, zanamivir, laninamivir, and peramivir) was evaluated against influenza A/H1N1pdm09, A/H3N2, and B viruses.
Momoko Mawatari, Reiko Saito, Akinobu Hibino, Hiroki Kondo, Ren Yagami, Takashi Odagiri, Ikumi Tanabe, Yugo Shobugawa, Japanese Influenza Collaborative Study Group   +8 more
doaj   +1 more source

Clinical and Postoperative Applications of Manuka Honey in Wound Healing: An Evidence‐Based Review

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Chronic and postoperative wounds remain challenging to manage, with high risks of infection, delayed healing and increased costs. Manuka honey offers antibacterial, anti‐inflammatory, antioxidant and tissue‐regenerative properties through methylglyoxal, phenolic compounds, high sugar content and low pH.
Ayman N. Alhabsi, Abdullah Al Lawati, Lubna Al Hashmi, Fatema Al‐Isaii, Alwaleed Alghammari, Srijit Das, Sheikhan Al Hashmi   +6 more
wiley   +1 more source