Results 71 to 80 of about 25,524 (191)

Outcomes of early oseltamivir treatment for hospitalized adult patients with community-acquired influenza pneumonia.

PLoS ONE, 2021
Early initiation of oseltamivir within 48 h to 5 days from illness onset has been associated with improved survival among patients with community-acquired influenza pneumonia.
Narongdet Kositpantawong, Smonrapat Surasombatpattana, Pisud Siripaitoon, Siripen Kanchanasuwan, Thanaporn Hortiwakul, Boonsri Charernmak, Ozioma Forstinus Nwabor, Sarunyou Chusri   +7 more
doaj   +1 more source

Real‐World Claims Data on Prescribed Drugs and the Associated Drug–Drug Interaction Risk in Sickle Cell Disease in the United States

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
Real‐world prescription data from 6230 adolescents and adults living with sickle cell disease (SCD) were combined with a drug–drug interaction (DDI) database to characterize the population‐level DDI risk. The findings support a DDI risk assessment for development of novel SCD therapies and during clinical management of SCD.ABSTRACTSickle cell disease ...
Rune Aabjerg Nørgaard, Laura Grenier, Peter Bruun‐Rasmussen, Ifeyinwa Osunkwo, Carolina Säll   +4 more
wiley   +1 more source

Neuraminidase inhibitors for influenza: a systematic review and meta-analysis of regulatory and mortality data

Health Technology Assessment, 2016
Background: Neuraminidase inhibitors (NIs) are stockpiled and recommended by public health agencies for treating and preventing seasonal and pandemic influenza. They are used clinically worldwide.
Carl J Heneghan, Igho Onakpoya, Mark A Jones, Peter Doshi, Chris B Del Mar, Rokuro Hama, Matthew J Thompson, Elizabeth A Spencer, Kamal R Mahtani, David Nunan, Jeremy Howick, Tom Jefferson   +11 more
doaj   +1 more source

From Real World Data to Real Impact: A Co‐Medication Framework for Lung Cancer to Advance DDI Assessment and Patient‐Centric Drug Development

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju, HeeJae Choi, Shilpa Madari, Annie Carlisle, Ashish Sharma, Christina Kunz, Fenglei Huang   +6 more
wiley   +1 more source

Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers.

, 2016
Oseltamivir and oseltamivir carboxylate concentrations were measured in venous plasma, venous blood, and capillary blood taken simultaneously from 24 healthy volunteers.

core   +1 more source

Volatile Relay Biosensing and Mobile Phone Imaging for Detection of Influenza Virus

Advanced Functional Materials, Volume 36, Issue 74, 14 September 2026.
Detection of volatile organic compounds is performed via a coupled enzymatic assay with mobile phone detection of the signal. Specific application demonstrated herein is the detection of influenza virus, across multiple levels of biological complexity, up to patient‐derived samples.
Dante G. Andersen, Josefine H. Jakobsen, Mikkel Høj Nielsen, Shreyans Chatterjee, Detlef Michel, Jan Münch, Rüdiger Gross, Alexander N. Zelikin   +7 more
wiley   +1 more source

Ultrathin Hydrogel Membranes Inspired by Soap Films Enable Physiologically Relevant Breathing Lung Models

Advanced Materials, Volume 38, Issue 53, 21 September 2026.
A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee, Gwang Myeong Kim, Wookyeom Kim, Fenny Soetanto, Gyungin Ryu, Taehun Chung, Youn Soo Kim, Junmin Lee, Hwa‐Rim Lee, Sungjune Jung   +9 more
wiley   +1 more source

Synthesis and Biological activities of Oseltamivir phosphate (Tamiflu), Oseltamivir and Its Derivatives [PDF]

, 2014
Oseltamivir  phosphate or TamifluTM 1, oseltamivir 2 and three new oseltamivir derivatives 11-13 were synthesized starting from (-)-shikimic acid 3.
Sritana-anant, Yongsak, Niyomdecha, Muhammad   +1 more
core  

Inhibition effect of oseltamivir for sialidase activities of oseltamivir-resistant and -sensitive viruses using 4MU-Neu5Ac or BTP3-Neu5Ac.

, 2016
Sialidase activities of oseltamivir-resistant 738 (red circle) and -sensitive 838 (blue square) were measured in the presence of ten-fold serial dilutions of oseltamivir by using BTP3-Neu5Ac (A) or 4MU-Neu5Ac (B).
Yuuki Kurebayashi (235568), Keiji Sahara (3167001), Kiyoshi Ikeda (508348), Chihiro Tamoto (3167004), Tadanobu Takahashi (235567), Tadamune Otsubo (508346), Nona Shibahara (832839), Hirohisa Wada (832844), Takashi Suzuki (8491), Tatsuya Yokozawa (3167007), Akira Minami (474027)   +10 more
core   +1 more source

Pandemic (H1N1) 2009 and Seasonal Influenza A (H1N1) Co-infection, New Zealand, 2009

Emerging Infectious Diseases, 2010
Co-infection with seasonal influenza A (H1N1) and pandemic (H1N1) 2009 could result in reassortant viruses that may acquire new characteristics of transmission, virulence, and oseltamivir susceptibility.
Matthew Peacey, Richard J. Hall, Stephanie Sonnberg, Mariette Ducatez, Shevaun Paine, Mackenzie Nicol, Jacqui C. Ralston, Don Bandaranayake, Virginia Hope, Richard J. Webby, Sue Huang   +10 more
doaj   +1 more source