Results 71 to 80 of about 24,935 (185)

Effectiveness of four types of neuraminidase inhibitors approved in Japan for the treatment of influenza.

open access: yesPLoS ONE, 2019
BACKGROUND:Neuraminidase inhibitors (NAIs) effectively treat influenza. The clinical effectiveness of four NAIs (oseltamivir, zanamivir, laninamivir, and peramivir) was evaluated against influenza A/H1N1pdm09, A/H3N2, and B viruses.
Momoko Mawatari   +8 more
doaj   +1 more source

Effect of Late Second to Early Third Trimester of Pregnancy on the Activity of Renal Organic Anion Transporters (OAT1 and OAT3): A Biomarker Study

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 465-474, August 2026.
Pregnant individuals take drugs throughout pregnancy and many of these drugs (e.g., antivirals, antibiotics) are eliminated by renal organic anion transporters (OAT) 1 and OAT3. In vivo studies with OAT1/3 substrate drugs suggest that pregnancy increases renal OAT1/3 activities by 1.5‐ to 1.8‐fold.
Aarzoo Thakur   +4 more
wiley   +1 more source

Risk Factors for Mortality Associated With Influenza Infection in Patients With Hematologic Malignancies: A Cross‐Sectional Descriptive Observational Study

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Cancer patients, especially those with hematologic malignancies (HMs), are considered among the most vulnerable groups at risk for severe outcomes from influenza infection. This study aimed to investigate influenza infection in patients with HMs and identify the risk factors associated with mortality.
Setayesh Sindarreh   +8 more
wiley   +1 more source

Population-Wide Emergence of Antiviral Resistance during Pandemic Influenza [PDF]

open access: yes, 2008
Background: The emergence of neuraminidase inhibitor resistance has raised concerns about the prudent use of antiviral drugs in response to the next influenza pandemic.
Wu, Jianhong   +13 more
core   +2 more sources

Efficacy of clarithromycin-naproxen-oseltamivir combination therapy versus oseltamivir alone in hospitalized pediatric influenza patients

open access: yes, 2021
Purpose: This study aimed to compare the safety and efficacy of clarithromycin-naproxen-oseltamivir combination therapy to that of oseltamivir therapy alone in hospitalized pediatric influenza patients.
Ching-Ying Huang   +9 more
core   +1 more source

Respiratory Viral Burden and Healthcare Utilization Among Pediatric Patients With Acute Respiratory Viral Infections in a Tertiary Care Center

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Respiratory viral infections, particularly Respiratory Syncytial Virus (RSV) and influenza, are major causes of pediatric morbidity, hospitalization, and healthcare strain during winter seasons. This study aims to evaluate the clinical and epidemiological burden of RSV and influenza in pediatric patients and assess associated ...
Shafiqa Alsharif
wiley   +1 more source

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo   +4 more
wiley   +1 more source

Pandemic (H1N1) 2009 and Seasonal Influenza A (H1N1) Co-infection, New Zealand, 2009

open access: yesEmerging Infectious Diseases, 2010
Co-infection with seasonal influenza A (H1N1) and pandemic (H1N1) 2009 could result in reassortant viruses that may acquire new characteristics of transmission, virulence, and oseltamivir susceptibility.
Matthew Peacey   +10 more
doaj   +1 more source

Synthesis and Biological activities of Oseltamivir phosphate (Tamiflu), Oseltamivir and Its Derivatives [PDF]

open access: yes, 2014
Oseltamivir  phosphate or TamifluTM 1, oseltamivir 2 and three new oseltamivir derivatives 11-13 were synthesized starting from (-)-shikimic acid 3.
Sritana-anant, Yongsak   +1 more
core   +1 more source

Cost-effectiveness Scatter plot: Empiric treatment with oseltamivir vs. Post RIDT treatment with oseltamivir.

open access: yes, 2016
Cost-effectiveness Scatter plot: Empiric treatment with oseltamivir vs. Post RIDT treatment with oseltamivir.
Jiuhong Wu (2615215)   +3 more
core   +1 more source

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