Results 91 to 100 of about 25,792 (254)

Activation of Shc1 Allows Oncostatin M to Induce RANKL and Osteoclast Formation More Effectively Than Leukemia Inhibitory Factor

open access: yesFrontiers in Immunology, 2019
Background and Purpose: The gp130 family of cytokines signals through receptors dimerizing with the gp130 subunit. Downstream signaling typically activates STAT3 but also SHP2/Ras/MAPK pathways.
Emma Persson   +7 more
doaj   +1 more source

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

open access: yesRare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu   +8 more
wiley   +1 more source

Oncostatin M is dispensable for the regulation of hematopoietic stem/progenitor cell traffic by neutrophils

open access: yesiScience
Summary: Hematopoietic stem/progenitor cell (HSPC) trafficking in and out of the bone marrow (BM) is essential for immune surveillance and hematopoietic balance.
Anna Rodella   +7 more
doaj   +1 more source

The Nuclear Protein HOXB13 Enhances Methylmercury Toxicity by Inducing Oncostatin M and Promoting Its Binding to TNFR3 in Cultured Cells

open access: yesCells, 2019
Homeobox protein B13 (HOXB13), a transcription factor, is related to methylmercury toxicity; however, the downstream factors involved in enhancing methylmercury toxicity remain unknown.
Takashi Toyama   +8 more
doaj   +1 more source

Beyond abundance: the impact of sampling design on effective population size estimates in capercaillie

open access: yesWildlife Biology, EarlyView.
Effective population size (Ne) is a useful parameter to evaluate the long‐term viability of populations. While obtaining enough field data from wild populations to estimate Ne directly is challenging, molecular techniques applied to non‐invasive samples provide an appealing alternative.
María‐José Bañuelos, Mario Quevedo
wiley   +1 more source

The Impact of the Contribution Micro-environment on Data Quality: The Case of OSM

open access: yes, 2017
OpenStreetMap (OSM) is the most successful example of Volunteered Geographic Information (VGI). It is also the most frequently used case study in research that focuses on VGI quality, as it is usually considered a proxy for other VGI projects.
G. Foody   +6 more
semanticscholar   +1 more source

Dutch dilemma: Housing prices and flood risk exposure

open access: yesReal Estate Economics, EarlyView.
Abstract This article studies the impact of flood risk exposure on housing prices in a major river delta. Analyzing 1.8 million property transactions from 1998 to 2023 in the Netherlands, we find an average price discount of 1.1%. We observe considerable heterogeneity in price effects driven by exposure intensity, institutional settings that vary ...
Piet Eichholtz   +2 more
wiley   +1 more source

VGI and crisis mapping in an emergency situation. Comparison of four case studies: Haiti, Kibera, Kathmandu, Centre Italy

open access: yesGEOmedia, 2017
Over the last decade new voluntary mapping patterns are commonly known as VGI – Volunteered Geographic Information – that is, geo-localized information created voluntarily and consciously by web users.
Lucia Saganeiti   +3 more
doaj  

The opposing effects of interferon-beta and oncostatin-M as regulators of cancer stem cell plasticity in triple-negative breast cancer

open access: yesBreast Cancer Research, 2019
Background Highly aggressive, metastatic and therapeutically resistant triple-negative breast cancers (TNBCs) are often enriched for cancer stem cells (CSC).
Mary R. Doherty   +7 more
doaj   +1 more source

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