Results 61 to 70 of about 1,148 (180)
Current State and Future Directions of Genetics and Genomics of Endophytic Fungi for Bioprospecting Efforts [PDF]
, 2021 The bioprospecting of secondary metabolites from endophytic fungi received great attention in the 1990s and 2000s, when the controversy around taxol production from Taxus spp. endophytes was at its height.
Haslinger, Kristina +2 more
core +2 more sources
Marine Drugs, 2023 The Arctic-derived fungus Eutypella sp. D-1 can produce numerous secondary metabolites, and some compounds exhibit excellent biological activity. Seven pimarane-type diterpenes, including three new compounds eutypellenone F (1), libertellenone Y (2), and
Yaodong Ning +9 more
doaj +1 more source
Beyond penicillin: the potential of filamentous fungi for drug discovery in the age of antibiotic resistance [PDF]
, 2023 Antibiotics are a staple in current medicine for the therapy of infectious diseases. However, their extensive use and misuse, combined with the high adaptability of bacteria, has dangerously increased the incidence of multi-drug-resistant (MDR) bacteria.
Borges, Anabela +3 more
core +2 more sources
Journal of Fungi, 2021 Endophytic fungi are one of prolific sources of bioactive natural products with potential application in biomedicine and agriculture. In our continuous search for antimicrobial secondary metabolites from Fusarium oxysporum R1 associated with traditional ...
Zhiyang Fu +5 more
doaj +1 more source
Desvendando o potencial bioativo de bactérias marinhas [PDF]
, 2021 Besides a primary metabolism, living organisms possess a secondary metabolism which allows for the production of secondary metabolites that, normally, are not fundamental to the organism’s growth and survival.
João, Susana Afonso
core
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
FEBS Open Bio, Volume 16, Issue 1, Page 68-78, January 2026.By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita +3 more
wiley +1 more source
Angewandte Chemie, Volume 136, Issue 20, May 13, 2024.The biosynthesis of newly identified alkaloids featuring unique heterobicyclic and spirocyclic isoquinolone skeletons, arizonamides and arizolidines, has been characterized. Notably, the non‐heme iron enzyme ParG demonstrated catalytic versatility in multiple oxidative reactions, including cyclization and ring reconstruction.
Mai‐Truc Pham +4 more
wiley +2 more sources
Marine Drugs, 2022 Deep-sea sediment-derived bacterium may make full use of self-genes to produce more bioactive metabolites to adapt to extreme environment, resulting in the discovery of novel metabolites with unique structures and metabolic mechanisms.
Wenping Ding +7 more
doaj +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT The fungi Fusarium guttiforme and Phytophthora palmivora were cultivated in four different media (Potato Dextrose Agar, Czapek, rice, and ISP2) and co‐cultured to stimulate fungal interactions and enhance secondary metabolite production. Promising extracts were fractionated, yielding compounds such as the iron complex of fusaric acid (1 ...
Vitor de Souza Mazucato +7 more
wiley +1 more source
Annals of MicrobiologyBackground Xylariaceous fungi represent a promising source of secondary metabolites with diverse biological functions. However, their metabolic capacity often remains underestimated under conventional cultivation.
Pitchapa Thongsuwan +5 more
doaj +1 more source