Results 141 to 150 of about 13,324 (270)

Early acclimatization to high altitude: Acid–base and fluid balance dynamics during the first 2 days at 3100 m

open access: yesExperimental Physiology, EarlyView.
Abstract Immediate responses to hypoxia at high altitude are hyperventilation and successive respiratory alkalosis. Alkalosis, in turn, can affect cerebrospinal fluid pH and ventilatory control. The kidneys compensate metabolically for respiratory alkalosis.
Elisabeth Skalla   +9 more
wiley   +1 more source

Influence of the Intervertebral Disc Microenvironment on Matrix Synthesis and Metabolism in Goat Nucleus Pulposus Cells

open access: yesJOR SPINE, Volume 9, Issue 1, March 2026.
Goat nucleus pulposus cells cultured under clinically relevant oxygen, glucose, pH, and osmolarity revealed pH to have the most influential impact on viability and glycosaminoglycan synthesis. Interactions between factors showed that disc cell behavior is shaped by the microenvironment, highlighting its importance in regenerative therapy design for the
Niamh Wilson   +5 more
wiley   +1 more source

A Practical Approach to Study Uncultivated Protists Using Single‐Cell Techniques for Electron Microscopy

open access: yesJournal of Eukaryotic Microbiology, Volume 73, Issue 2, March/April 2026.
ABSTRACT Protists represent a significant portion of eukaryotic diversity with a wide range of ecological roles, lifestyles, and diverse morphological traits. Despite their widespread importance in ecological systems and their potential as model organisms, most protist lineages remain poorly characterized, in part due to their small size and the fact ...
Maia V. Palka   +4 more
wiley   +1 more source

Facile Bottom‐Up Assembly of Photonic Micropatterns via Surface‐Guided Colloidal Crystallization

open access: yesAdvanced Materials, Volume 38, Issue 7, 2 February 2026.
High‐resolution photonic micropatterns with vivid structural colors are fabricated through bottom‐up assembly, guided by surface‐dependent regioselective heterogeneous nucleation and crystal growth of colloidal particles. Full‐spectrum color tunability is achieved by controlling particle size and interparticle attraction, while in situ color mixing is ...
Yongseok Jung   +3 more
wiley   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun   +15 more
wiley   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha   +13 more
wiley   +1 more source

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