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Osteoarthritis [PDF]

open access: yesDisease-a-Month, 2006
Osteoarthritis (OA), the syndrome of joint pain and dysfunction caused by joint degeneration, affects more people than any other joint disease. In most instances joint degeneration develops in the absence of an identifiable cause, but increasing age, excessive joint loading, and joint abnormalities and insults increase the risk of OA. Articular surface
David J, Hunter, David T, Felson
semanticscholar   +7 more sources

Osteoarthritis [PDF]

open access: yesNature Reviews Disease Primers, 2016
Osteoarthritis (OA) is the most common joint disorder, is associated with an increasing socioeconomic impact owing to the ageing population and mainly affects the diarthrodial joints. Primary OA results from a combination of risk factors, with increasing age and obesity being the most prominent.
Johanne, Martel-Pelletier   +9 more
  +8 more sources

Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021

open access: yesThe Lancet Rheumatology, 2023
Summary Background Osteoarthritis is the most common form of arthritis in adults, characterised by chronic pain and loss of mobility. Osteoarthritis most frequently occurs after age 40 years and prevalence increases steeply with age.
Jaimie D Steinmetz   +166 more
semanticscholar   +1 more source

Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Osteoarthritis (OA) is the most common joint disease, affecting an estimated more than 240 million people worldwide, including an estimated more than 32 million in the US.
J. Katz, Kaetlyn R. Arant, R. Loeser
semanticscholar   +1 more source

Psychosocial and individual factors affecting Quality of Life (QoL) in patients suffering from Achilles tendinopathy: a systematic review

open access: yesBMC Musculoskeletal Disorders, 2022
Background Achilles tendinopathy (AT) is a joint condition that causes functional restrictions and pain. This condition negatively impacts patients' social connectedness and psychological well-being, reducing their quality of life (QoL). This review aims
Josep Verges   +5 more
doaj   +1 more source

Prevalence Trends of Site‐Specific Osteoarthritis From 1990 to 2019: Findings From the Global Burden of Disease Study 2019

open access: yesArthritis & Rheumatology, 2022
To estimate systematic and anatomic site–specific age‐standardized prevalence rates (ASRs) and analyze the secular trends of osteoarthritis (OA) at global, regional, and national levels.
Huibin Long   +7 more
semanticscholar   +1 more source

Dynamic weight-bearing test during jumping: A sensitive outcome measure of chronic osteoarthritis pain in rats

open access: yesHeliyon, 2021
Pain due to osteoarthritis (OA) often occurs during locomotion in the vertical direction when joints are subjected to high mechanical load, e.g. during standing up from a chair or using stairs.
Andreas Westhof   +3 more
doaj   +1 more source

Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species

open access: yesArthritis Research & Therapy, 2021
Background Osteoarthritis (OA) is a disease of the whole joint, with articular cartilage breakdown as a major characteristic. Inflammatory mediators, proteases, and oxidants produced by chondrocytes are known to be responsible for driving cartilage ...
Anne Gigout   +6 more
doaj   +1 more source

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

open access: yesArthritis care & research, 2020
To develop an evidence‐based guideline for the comprehensive management of osteoarthritis (OA) as a collaboration between the American College of Rheumatology (ACR) and the Arthritis Foundation, updating the 2012 ACR recommendations for the management of
S. Kolasinski   +31 more
semanticscholar   +1 more source

SYSADOAs: do their origin and quality make a difference in efficacy and safety?

open access: yesGlobal Rheumatology, 2021
Symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) comprise a heterogeneous group of drugs with a long-term effect on the symptoms of osteoarthritis.
Marianna Vitaloni   +2 more
doaj   +1 more source

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