Results 1 to 10 of about 653,878 (339)

Osteoarthritis [PDF]

BMJ, 2006
Osteoarthritis is a leading cause of disability and source of societal cost in older adults. With an ageing and increasingly obese population, this syndrome is becoming even more prevalent than in previous decades.
D. Hunter, D. Felson
semanticscholar   +7 more sources

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Cell, 2021
Summary Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 11 ...
Cindy G Boer, Konstantinos Hatzikotoulas, Lorraine Southam   +2 more
exaly   +2 more sources

Osteoarthritis [PDF]

Nature Reviews Disease Primers, 2016
Osteoarthritis (OA) is the most common joint disorder, is associated with an increasing socioeconomic impact owing to the ageing population and mainly affects the diarthrodial joints. Primary OA results from a combination of risk factors, with increasing age and obesity being the most prominent.
Johanne, Martel-Pelletier, Andrew J, Barr, Flavia M, Cicuttini, Philip G, Conaghan, Cyrus, Cooper, Mary B, Goldring, Steven R, Goldring, Graeme, Jones, Andrew J, Teichtahl, Jean-Pierre, Pelletier   +9 more
  +8 more sources

Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021

The Lancet Rheumatology, 2023
Summary Background Osteoarthritis is the most common form of arthritis in adults, characterised by chronic pain and loss of mobility. Osteoarthritis most frequently occurs after age 40 years and prevalence increases steeply with age.
Jaimie D Steinmetz, Garland T Culbreth, Lydia M Haile, Quinn Rafferty, Justin Lo, K. Fukutaki, Jessica A Cruz, Amanda E Smith, S. Vollset, P. M. Brooks, M. Cross, A. Woolf, Hailey Hagins, M. Abbasi-Kangevari, Aidin Abedi, I. Ackerman, Hubert Amu, B. Antony, J. Arabloo, A. Aravkin, A. Argaw, A. Artamonov, Tahira Ashraf, Amadou Barrow, L. Bearne, I. Benseñor, Alemshet Yirga Berhie, Nikha Bhardwaj, Pankaj Bhardwaj, Vijayalakshmi S. Bhojaraja, Ali Bijani, P. Briant, A. Briggs, Nadeem Shafique Butt, J. Charan, Vijay Kumar Chattu, F. Cicuttini, Kaleb Coberly, O. Dadras, X. Dai, L. Dandona, R. Dandona, Katie de Luca, E. Denova-Gutiérrez, S. Dharmaratne, M. Dhimal, M. Dianatinasab, K. Dreinhoefer, Muhammed Elhadi, Umar Farooque, H. Farpour, I. Filip, F. Fischer, M. Freitas, B. Ganesan, Belete Negese Belete Gemeda, Tamiru Getachew, S. Ghamari, A. Ghashghaee, T. Gill, Mahaveer Golechha, D. Golinelli, Bhawna Gupta, Veera Gupta, Vikrant Gupta, Rasool Haddadi, N. Hafezi-Nejad, R. Halwani, S. Hamidi, Asif Hanif, N. I. Harlianto, J. Haro, J. Hartvigsen, Simon Iain Hay, J. Hébert, G. Heidari, Mohammad-Salar Hosseini, M. Hosseinzadeh, A. Hsiao, I. Ilic, M. Ilic, L. Jacob, R. Jayawardena, Ravi Prakash Jha, J. Jonas, N. Joseph, Himal Kandel, I. Karaye, Md Jobair Khan, Y. Kim, Ali-Asghar Kolahi, O. Korzh, Rajasekaran Koteeswaran, V. Krishnamoorthy, G. Kumar, Narinder Kumar, Sang-Woong Lee, Stephen S. Lim, S. Lobo, G. Lucchetti, Mohammad-Reza Malekpour, A. A. Malik, L. G. Mandarano-Filho, S. Martini, A. Mentis, Mohamed Mesregah MD, T. Meštrović, E. Mirrakhimov, A. Misganaw, R. Mohammadpourhodki, A. Mokdad, S. Momtazmanesh, S. Morrison, C. Murray, H. Nassereldine, Henok Biresaw Netsere, Sandhya Neupane Kandel, M. Owolabi, S. Panda-Jonas, Anamika Pandey, Shrikant Pawar, P. Pedersini, J. Pereira, A. Radfar, M. Rashidi, D. Rawaf, S. Rawaf, Reza Rawassizadeh, S. Rayegani, Daniel Ribeiro, Leonardo Roever, B. Saddik, A. Sahebkar, Salehi, L. SÀNCHEZ RIERA, F. Sanmarchi, Milena M. Santric-Milicevic, S. Shahabi, M. Shaikh, Elaheh Shaker, Mohammed Shannawaz, Rajendra Sharma, Saurabh Sharma, J. Shetty, R. Shiri, P. Shobeiri, D. Silva, A. Singh, Jasvinder A. Singh, Surjit Singh, S. T. Skou, H. Slater, M. Soltani‐Zangbar, A. Starodubova, A. Tehrani-Banihashemi, Sahel Valadan Tahbaz, Pascual Valdez, Bay Vo, L. G. Vu, Yuan-Pang Wang, Seyed Hossein Yahyazadeh Jabbari, N. Yonemoto, Ismaeel Yunusa, L. March, K. Ong, T. Vos, J. Kopec   +166 more
semanticscholar   +1 more source

Psychosocial and individual factors affecting Quality of Life (QoL) in patients suffering from Achilles tendinopathy: a systematic review

BMC Musculoskeletal Disorders, 2022
Background Achilles tendinopathy (AT) is a joint condition that causes functional restrictions and pain. This condition negatively impacts patients' social connectedness and psychological well-being, reducing their quality of life (QoL). This review aims
Josep Verges, Nina Martínez, Aina Pascual, Marco Bibas, Manel Santiña, Gil Rodas   +5 more
doaj   +1 more source

Diagnosis and treatment of hip and knee osteoarthritis: A review

Journal of the American Medical Association (JAMA), 2021
Importance: Osteoarthritis (OA) affects more than 240 million people worldwide and is the most frequent reason for activity limitation in adults. This review focuses on hip and knee OA. Observations: OA is the most common type of arthritis.
J. Katz, Kaetlyn R. Arant, R. Loeser
semanticscholar   +1 more source

Dynamic weight-bearing test during jumping: A sensitive outcome measure of chronic osteoarthritis pain in rats

Heliyon, 2021
Pain due to osteoarthritis (OA) often occurs during locomotion in the vertical direction when joints are subjected to high mechanical load, e.g. during standing up from a chair or using stairs.
Andreas Westhof, Kerstin Kleinschmidt-Doerr, Martin Michaelis, Christian Brenneis   +3 more
doaj   +1 more source

Prevalence Trends of Site‐Specific Osteoarthritis From 1990 to 2019: Findings From the Global Burden of Disease Study 2019

Arthritis & Rheumatology, 2022
To estimate systematic and anatomic site–specific age‐standardized prevalence rates (ASRs) and analyze the secular trends of osteoarthritis (OA) at global, regional, and national levels.
Huibin Long, Qiang Liu, Heyong Yin, Kai Wang, Naicheng Diao, Yuqing Zhang, Jianhao Lin, A. Guo   +7 more
semanticscholar   +1 more source

Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species

Arthritis Research & Therapy, 2021
Background Osteoarthritis (OA) is a disease of the whole joint, with articular cartilage breakdown as a major characteristic. Inflammatory mediators, proteases, and oxidants produced by chondrocytes are known to be responsible for driving cartilage ...
Anne Gigout, Donata Harazin, Louise M. Topping, Didier Merciris, Sven Lindemann, Christian Brenneis, Ahuva Nissim   +6 more
doaj   +1 more source

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

Arthritis care & research, 2020
To develop an evidence‐based guideline for the comprehensive management of osteoarthritis (OA) as a collaboration between the American College of Rheumatology (ACR) and the Arthritis Foundation, updating the 2012 ACR recommendations for the management of
S. Kolasinski, T. Neogi, M. Hochberg, C. Oatis, G. Guyatt, J. Block, L. Callahan, C. Copenhaver, Carole V Dodge, D. Felson, Kathleen Gellar, W. Harvey, G. Hawker, Edward Herzig, C. Kwoh, A. Nelson, J. Samuels, C. Scanzello, D. White, B. Wise, R. Altman, D. DiRenzo, J. Fontanarosa, Gina Giradi, Mariko L. Ishimori, D. Misra, A. Shah, A. Shmagel, L. Thoma, M. Turgunbaev, Amy S. Turner, J. Reston   +31 more
semanticscholar   +1 more source