Results 51 to 60 of about 302,871 (285)

Patient-specific risk profile associated with early-onset primary osteoarthritis of the shoulder: is it really primary? [PDF]

open access: hybrid, 2021
Fabian Plachel   +4 more
openalex   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

open access: yesArthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead   +4 more
wiley   +1 more source

Playing sport injured is associated with osteoarthritis, joint pain and worse health-related quality of life: a cross-sectional study

open access: yesBMC Musculoskeletal Disorders, 2020
Background Sports participants are faced with the decision to continue or cease play when injured. The implications of playing sport while injured on joint health and health-related quality of life (HRQoL) has not been investigated.
Garrett S. Bullock   +4 more
doaj   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer   +5 more
wiley   +1 more source

RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family

open access: yesNature Communications, 2019
Osteoarthritis is characterised by degeneration of joint cartilage. Here the authors show that the RNA-binding protein ZFP36L1 is upregulated in chondrocytes of humans and mice with osteoarthritis, and that its knockdown in mouse joints protects ...
Young-Ok Son   +4 more
doaj   +1 more source

Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo

open access: yesJournal of Translational Medicine, 2017
Background Sprifermin (recombinant human fibroblast growth factor 18) is in clinical development as a potential disease-modifying osteoarthritis drug (DMOAD).
Ditte Reker   +7 more
doaj   +1 more source

Financial Distress and Its Determinants in Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler   +5 more
wiley   +1 more source

Complicated thromboembolic prophylaxis in the treatment of septic gonitis – case report

open access: yesPediatria i Medycyna Rodzinna, 2015
In this paper the case of a patient subjected to orthopaedic treatment with a history of a number of internal comorbidities, cardiac ones in particular, has been reported. Cardiac comorbidities were related to the implantation of a VVI pacemaker.
Adrian Brychcy   +2 more
doaj   +1 more source

Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐89 with CLBP from 3 VA medical centers underwent baseline testing, randomization to ABC or UC and 12 months follow ...
Debra K. Weiner   +9 more
wiley   +1 more source

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