Results 121 to 130 of about 2,079,758 (368)

Balancing porosity and mechanical properties of titanium samples to favor cellular growth against bacteria [PDF]

, 2019
Two main problems limit the success of titanium implants: bacterial infection, which restricts their osseointegration capacity; and the stiffness mismatch between the implant and the host cortical bone, which promotes bone resorption and risk of fracture.
Beltrán, Ana M., Cauich-Rodríguez, Juan V., Civantos, Ana, Domínguez-Trujillo, Cristina, García-Moreno, Francisco, Garvi Higueras, María Dolores, Guzmán, Julio J., Lebrato Martínez, Julián, Rodríguez-Ortiz, José Antonio, Torres Hernández, Yadir   +9 more
core   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Glial cell line-derived neurotrophic factor influences proliferation of osteoblastic cells [PDF]

, 2012
Little is known about the role of neurotrophic growth factors in bone metabolism. This study investigated the short-term effects of glial cell line-derived neurotrophic factor (GDNF) on calvarial-derived MC3T3-E1 osteoblasts.
Airaksinen, Baldassarre, Ben A. Scheven, Chen, Costantini, Cuccuru, De Ceuninck, Declercq, Edery, Figiel, Forander, Frost, Gale, Gao, Garcia, Gattei, Gattei, Glass, Gowen, Hashino, Hefferan, Hellmich, Janssens, Jiang, Kashani, Krieglstein, Kuno, Kurozumi, Lencel, Li, Luukko, Modrowski, Nakayama, Nanes, Nosrat, Nosrat, Paratcha, Paul R. Cooper, Peterziel, Rawlinson, Remy, Remy, Robinson, Saarma, Sariola, Scheven, Scheven, Shi, Subramaniam, van den Bos, Wang, Wang, Yajima, Yan, Yanaga, Zins, Zoe Gale   +56 more
core   +2 more sources

Minireview: Transcriptional Control of Osteoblast Differentiation [PDF]

Endocrinology, 2001
The last 5 yr have witnessed major progress in skeleton biology. One of these areas of progress has been the partial elucidation of the transcriptional mechanisms of osteoblast differentiation and their conservation between mouse and human. Cbfal, or runx2, a homolog of the Drosophila Runt protein serves both as the earliest transcriptional regulator ...
openaire   +2 more sources

Exploiting Two‐Photon Lithography, Deposition, and Processing to Realize Complex 3D Magnetic Nanostructures

Advanced Functional Materials, EarlyView.
Two‐photon lithography (TPL) enables 3D magnetic nanostructures with unmatched freedom in geometry and material choice. Advances in voxel control, deposition, and functionalization open pathways to artificial spin ices, racetracks, microrobots, and a number of additional technological applications.
Joseph Askey, Arjen van den Berg, Sandra Ruiz Gomez, Claire Donnelly, Dirk Grundler, Sam Ladak   +5 more
wiley   +1 more source

MicroRNA-34a prevents postmenopausal osteoporosis by promoting osteoclasts-induced osteoblasts differentiation and downregulating the proinflammatory cytokines [PDF]

, 2022
Wentao Lv, Xiaojie Chu, Zhonglei Bao, Xinyuan zhang, Jia Jia, Liyan Wang   +5 more
openalex   +1 more source

Resveratrol Attenuates Lipopolysaccharides (LPS)-Induced Inhibition of Osteoblast Differentiation in MC3T3-E1 Cells

Medical Science Monitor, 2018
Background LPS-inhibited osteoblastic differentiation plays an important role in the pathogenesis of osteomyelitis. Thus, searching for drugs that affect LPS-mediated osteoblastic differentiation may be crucial in developing therapies for osteomyelitis ...
Jun Ma, Zhuo Wang, Jianquan Zhao, Wujun Miao, T. Ye, Aimin Chen   +5 more
semanticscholar   +1 more source

Wdr5 Is Essential for Osteoblast Differentiation

Journal of Biological Chemistry, 2008
Wdr5 is developmentally expressed in osteoblasts and accelerates osteoblast differentiation in vitro and in vivo. To address whether Wdr5 is essential for osteoblast differentiation, plasmid-based small interfering RNAs were used to stably suppress endogenous Wdr5 protein levels in MC3T3-E1 cells.
Eric D, Zhu, Marie B, Demay, Francesca, Gori   +2 more
openaire   +2 more sources

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Is there a role for vitamin C in preventing osteoporosis and fractures?:A review of the potential underlying mechanisms and current epidemiological evidence [PDF]

, 2014
Osteoporosis and related fractures are a major global health issue, but there are few preventative strategies. Previously reported associations between higher intakes of fruits and vegetables and skeletal health have been suggested to be partly ...
Ailsa A. Welch, Amy Jennings, Andrew R. Hart, Bates, Bates, Canoy, Drewnowski, Gottlieb, Henriette Finck, Hill, Hoffer, Kaptoge, Lanham-New, Myllyla, New, New, Otsuka, Pradel, Prynne, Sahni, Scrimshaw, Sowers, Tucker, Wolf   +23 more
core   +1 more source