Results 221 to 230 of about 2,079,758 (368)

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

β-Catenin: A Key Molecule in Osteoblast Differentiation. [PDF]

Biomolecules
Wróbel E, Wojdasiewicz P, Mikulska A, Szukiewicz D.   +3 more
europepmc   +1 more source

Methylglyoxal compromises callus mineralization and impairs fracture healing through suppression of osteoblast terminal differentiation

Tetsuya Seto, Kiminori Yukata, Shunya Tsuji, Yusuke Takeshima, Takeshi Honda, Akihiko Sakamoto, Kenji Takemoto, Hiroki Sakai, Mayu Matsuo, Yurika Sasaki, Mizuki Kaneda, Mitsuki Yoshimura, Atsushi Mihara, Kazuya Uehara, Aira Matsugaki, Takayoshi Nakano, Koji Harada, Yoshiro Tahara, Keiko Iwaisako, Ryoji Yanai, Norihiko Takeda, Takashi Sakai, Masataka Asagiri   +22 more
openalex   +1 more source

Normoglycemia Partially Recovers the Disrupted Osteoblast Differentiation of Mesenchymal Stem Cells Induced by Type 1 But Not Type 2 Diabetes Mellitus

, 2022
Denise Weffort, Letícia Faustino Adolpho, Alann Thaffarell Portilho Souza, Gileade Pereira Freitas, Helena Bacha Lopes, Fabíola Singaretti Oliveira, Rayana Longo Bighetti‐Trevisan, Letícia Pitol‐Palin, Dóris Hissako Matsushita, Roberta Okamoto, Márcio Mateus Beloti, Adalberto Luiz Rosa   +11 more
openalex   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

Knockdown of GCNT2 promoted osteoblast differentiation by activating PI3K/AKT/mTOR pathway in osteoblasts. [PDF]

Sci Rep
Huang Y, Wang S, Hu D, Zhang L, Shi S.
europepmc   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Interactions Between HEP Peptide and EGFR Involved in the Osteoblast Differentiation. [PDF]

Foods
Gan J, Huang Y, Jian M, Chen Y, Jiang Y, Qiao Y, Li Y.   +6 more
europepmc   +1 more source

Aging impairs osteoblast differentiation of mesenchymal stem cells grown on titanium by favoring adipogenesis [PDF]

, 2016
Rodrigo Paolo Flores Abuna, Camila Tami Stringhetta-Garcia, Leonardo Pimentel FIORI, Rita Cássia Menegati Dornelles, Adalberto Luiz Rosa, Márcio Mateus Beloti   +5 more
openalex   +1 more source

Experiment K-6-03. Gravity and skeletal growth, part 1. Part 2: Morphology and histochemistry of bone cells and vasculature of the tibia; Part 3: Nuclear volume analysis of osteoblast histogenesis in periodontal ligament cells; Part 4: Intervertebral disc swelling pressure associated with microgravity [PDF]

Bone area, bone electrophysiology, bone vascularity, osteoblast morphology, and osteoblast histogenesis were studied in rats associated with Cosmos 1887.
Berretta, D., Doty, S., Durnova, G., Garetto, L., Gonsalves, M., Gott, S., Hargens, A., Holton, E., Kaplansky, A., Roberts, W.   +9 more
core   +1 more source