Impaired MC3T3-E1 osteoblast differentiation triggered by oncogenic HRAS is rescued by the farnesyltransferase inhibitor Tipifarnib. [PDF]
Andrasch Y +7 more
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ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
SARS-CoV-2 Impairs Osteoblast Differentiation Through Spike Glycoprotein and Cytokine Dysregulation. [PDF]
Freiberger RN +9 more
europepmc +1 more source
HIV Modulates Osteoblast Differentiation via Upregulation of RANKL and Vitronectin. [PDF]
Freiberger RN +8 more
europepmc +1 more source
Preferred Orientation of Hydroxyapatite Ceramics Along the c-Axis Promotes Osteoblast Differentiation. [PDF]
Suzuki K +4 more
europepmc +1 more source
Berberine Derivative Compound 13 as a Potent Promoter of Osteoblast Differentiation via Akt and PKC Signaling Pathways. [PDF]
Piao M, Han YH, Lee KY.
europepmc +1 more source
Unveiling the Role of Sik1 in Osteoblast Differentiation: Implications for Osteoarthritis. [PDF]
Tian K +15 more
europepmc +1 more source
Frequency-Regulated Repeated Micro-Vibration Promotes Osteoblast Differentiation Through BMP Signaling in MC3T3-E1 Cells. [PDF]
Matsushita A +10 more
europepmc +1 more source
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Role of Cbfa1 in osteoblast differentiation and function
Seminars in Cell and Developmental Biology, 2000Among the multiple cell lineages whose differentiation is affected by a runt-related gene the osteoblast is a relative newcomer. Molecular biology, developmental biology and mouse and human genetic studies have demonstrated that Cbfa1 is a critical regulator of osteoblast differentiation in vertebrates.
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Bioenergetic Metabolism In Osteoblast Differentiation
Current Osteoporosis Reports, 2022Osteoblasts are responsible for bone matrix production during bone development and homeostasis. Much is known about the transcriptional regulation and signaling pathways governing osteoblast differentiation. However, less is known about how osteoblasts obtain or utilize nutrients to fulfill the energetic demands associated with osteoblast ...
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