Results 191 to 200 of about 18,733 (222)
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A novel human osteoblast–derived severe combined immunodeficiency mouse model of bone metastasis
Journal of Neurosurgery: Spine, 2006Object One of the major difficulties of conducting bone metastasis research is the lack of adequate models for studying the bone–tumor microenvironment. The limitations of current in vivo models include the following: non-human tumor or bone, variable reproducibility, limited supply, and an inability to be easily manipulated.
James, Schuster +2 more
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Osteoblast-Derived PTHRP and Breast Cancer Bone Metastasis
2004Abstract : Metastases to bone, lung, and other organs are common and catastrophic consequences of breast cancer progression. There is therefore an urgent need to improve current therapies that address cancer growth and spread. Parathyroid hormone-related protein (PTHrP, also referred to as parathyroid hormone-like protein [PTHLP]) is a secreted factor ...
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Targeting Osteoblastic Bone Metastasis with a Novel Site Restricted Gene Therapy
2004Abstract : Continuing from the previous two years work on this project, encouraging data was also obtained in year 3. Effectiveness of the Ad- BSP-Ela viral contrast was again demonstrated in the intraosseous model of prostate cancer bone metastasis. Further tests were completed and, as such, it appears that low dose systemic taxotere administration in
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Rectal carcinoid tumor with bone marrow and osteoblastic bone metastasis: A case report
2007Rectal carcinoids comprise 12.6% of all carcinoid tumors and represent the third largest group of the gut carcinoids. A 64-year-old woman was diagnosed as high-grade neuroendocrine carcinoma. She had liver, bone, and bone marrow metastasis. Carcinoid syndrome was diagnosed due to diarrhea, nausea, vomiting, tachycardia, and high level of 24-hour ...
DENİZ, Kemal +7 more
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Gan to kagaku ryoho. Cancer & chemotherapy, 1999
A 52-year-old woman with painful osteoblastic bone metastasis received pamidronate therapy which resulted in marked pain relief with a normalization of elevated tumor marker levels. However, the patient complained of increased pain after the 26th pamidronate infusion.
S, Oura +5 more
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A 52-year-old woman with painful osteoblastic bone metastasis received pamidronate therapy which resulted in marked pain relief with a normalization of elevated tumor marker levels. However, the patient complained of increased pain after the 26th pamidronate infusion.
S, Oura +5 more
openaire +1 more source
Novel approaches to target the microenvironment of bone metastasis
Nature Reviews Clinical Oncology, 2021Lorenz C Hofbauer +2 more
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Materials design for bone-tissue engineering
Nature Reviews Materials, 2020Mani Diba, Antonios G Mikos
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Hypercalcemia and cancer: Differential diagnosis and treatment
Ca-A Cancer Journal for Clinicians, 2018Sarah B Fisher
exaly
Understanding biology to tackle the disease: Multiple myeloma from bench to bedside, and back
Ca-A Cancer Journal for Clinicians, 2014Giada Bianchi
exaly