Results 91 to 100 of about 42,214 (280)

Zinc and Strontium‐Doped Titania Nanotube Surfaces Enhance Antibacterial Activity and Increase Osteogenic Differentiation of Mesenchymal Stem Cells

Advanced NanoBiomed Research, EarlyView.
Bacterial infection and poor integration often lead to orthopedic implant failure. Modifying implant surfaces can improve osseointegration. Titanium has been engineered to form titania nanotubes doped with zinc and strontium. These surfaces were evaluated for antibacterial effects and their ability to promote osteogenic differentiation in stem cells ...
Abhishek Bhattacharjee, Aniruddha Vijay Savargaonkar, Bruno L. Pereira, Paulo Soares, Ketul C. Popat   +4 more
wiley   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte

Poultry Science
: Fatty liver hemorrhage syndrome (FLHS) is the leading cause of noninfectious mortality in caged layers worldwide. Osteocalcin (OCN) is a protein secreted by osteoblasts, and its undercarboxylated form (ucOCN) acts as a multifunctional hormone that ...
W.J. Tu, Y.H. Zhang, X.T. Wang, M. Zhang, K.Y. Jiang, S. Jiang   +5 more
doaj   +1 more source

Programmatic regulation of macrophage polarization by HAp@MXene nanocomposites to promote bone repair

BMEMat, EarlyView.
HAp@MXene nanocomposites could achieve the programmed regulation of macrophage polarization. They first induce M1 polarization through magnetoelectric induction to combat infection. Subsequently, controlled Ca2+ release drives M2 polarization to promote tissue regeneration. This dual mechanism accelerates bone defect repair and highlights the potential
Laisen Cui, Haina Huang, Yubo Zheng, Jiahao Zhang, Han Hai, Kai Bian, Zhichao Feng, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shan Lu, Bojun Xie, Ke Gao, Benjie Wei, Ya Liu, Chunhui Sun, Hong Liu, Chao Liu   +16 more
wiley   +1 more source

EVALUATION OF SERUM OSTEOCALCIN (OC) AS AN INDEX OF ALTERED BONE METABOLISM IN CHILDREN AND ADULTS [PDF]

, 1985
K. Kruse
openalex   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

Regulation of Osteocalcin Production and Bone Resorption by 1,25-Dihydroxyvitamin D3 in Mouse Long Bones: Interaction with the Bone-Derived Growth Factors TGF-β and IGF-I [PDF]

, 1998
Ada Staal, W. M. C. Geertsma-Kleinekoort, G.J.C.M. van den Bemd, C.J. Buurman, J.C. Birkenhäger, Huibert A. P. Pols, Johannes P.T.M. van Leeuwen   +6 more
openalex   +1 more source

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

Exploration, EarlyView.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao, Xiaoye Li, Ao He, Meng Ding, Yu Zhang, Zhuo Dai, Qiang Li, Weijun Xiu, Yanling Hu, Yongbin Mou, Dongliang Yang, Heng Dong   +11 more
wiley   +1 more source

An extract from pork bones containing osteocalcin improves glucose metabolism in mice by oral administration [PDF]

, 2016
Akiko Mizokami, DaGuang Wang, Mitsuru Tanaka, Jing Gao, Hiroshi Takeuchi, Toshiro Matsui, Masato Hirata   +6 more
openalex   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

Interdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao, Yue Cao, Zhengting Wu, Yingqi Cao, Qi You, Yuanyuan Xia, Xuejun Tan, Dongxiao Li, Tianxin Qiu, Xiuping Cai, Zhaodi Guo, Lei Zheng, Kewei Zhao   +12 more
wiley   +1 more source