Results 21 to 30 of about 71,141 (203)

Relation between osteocalcin and the energy metabolism in obesity [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. Numerous findings have indicated the potential relation between the osteocalcin, the traditional parameter of bone turnover and the regulation of energy metabolism.
Nikolić Stanislava, Ćurić Nikola, Ilinčić Branislava, Stošić Zoran, Tomić-Naglić Dragana, Benc Damir   +5 more
doaj   +1 more source

The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation [PDF]

, 2010
Background: Clock genes and their protein products regulate circadian rhythms in mammals but have also been implicated in various physiological processes, including bone formation.
Maronde, Erik, Schilling, Arndt, Seitz, Sebastian, Schinke, Thorsten, Schmutz, Isabelle, Horst, Gijsbertus van der, Amling, Michael, Albrecht, Urs   +7 more
core   +1 more source

Undercarboxylated osteocalcin reverts insulin resistance induced by endoplasmic reticulum stress in human umbilical vein endothelial cells

Scientific Reports, 2017
Osteocalcin has been considered to be an important regulator of energy metabolism in type 2 diabetes mellitus (T2DM). However, the mechanism underlying the involvement of uncarboxylated osteocalcin in the vascular complications of T2DM is not fully ...
Qinyue Guo, Huixia Li, Lin Xu, Shufang Wu, Hongzhi Sun, Bo Zhou   +5 more
doaj   +1 more source

Association between serum ferritin and osteocalcin as a potential mechanism explaining the iron-induced insulin resistance. [PDF]

PLoS ONE, 2013
BACKGROUND: Increased iron stores are associated with increased risk of type 2 diabetes, however, the mechanisms underlying these associations are poorly understood.
Martí Juanola-Falgarona, José Cándido-Fernández, Jordi Salas-Salvadó, Miguel A Martínez-González, Ramón Estruch, Miquel Fiol, Victoria Arija-Val, Mònica Bulló, PREDIMED Study Investigators   +8 more
doaj   +1 more source

Enhanced osteogenic differentiation in zoledronate-treated osteoporotic patients [PDF]

, 2017
Bisphosphonates are well known inhibitors of osteoclast activity and thus may be employed to influence osteoblast activity. The present study was designed to evaluate the in vivo effects of zoledronic acid (ZA) on the proliferation and osteoblastic ...
Carbonare, Luca Dalle, Dellantonio, Alessandra, Malerba, Giovanni, Mori, Antonio, Mottes, Monica, Plebani, Mario, Valenti, Maria Teresa, Zaninotto, Martina   +7 more
core   +3 more sources

Osteocalcin and Metabolic Syndrome

Clinical Medicine Insights: Endocrinology and Diabetes, 2023
Introduction: Metabolic syndrome which is a syndrome complex that is associated with insulin resistance. Osteocalcin (OC), a bone derived protein has been found to decrease insulin resistance and stimulate production of insulin from the pancreas. Serum osteocalcin levels correlate with body mass index (BMI) and waist circumference.
Aaditya Viswanath, Sudha Vidyasagar, Cynthia Amrutha Sukumar   +2 more
openaire   +3 more sources

Circulating osteocalcin is associated with time in range and other metrics assessed by continuous glucose monitoring in type 2 diabetes

Diabetology & Metabolic Syndrome, 2022
Background Osteocalcin, a protein secreted mainly by mature osteoblasts, has been shown to be involved in glucose metabolism through various pathways.
Jun Liu, Yinghua Wei, Pu Zang, Wei Wang, Zhouqin Feng, Yanyu Yuan, Hui Zhou, Zhen Zhang, Haiyan Lei, Xinyi Yang, Jun Liu, Bin Lu, Jiaqing Shao   +12 more
doaj   +1 more source

Interactions between Serum Adipokines and Osteocalcin in Older Patients with Hip Fracture

International Journal of Endocrinology, 2012
Introduction. Experiments on genetically modified animals have discovered a complex cross-regulation between adipokines (leptin, adiponectin) and osteocalcin. The relationships between these molecules in human osteoporosis are still unclear. We evaluated
Alexander Fisher, Wichat Srikusalanukul, Michael Davis, Paul Smith   +3 more
doaj   +1 more source

Biomarkers of vascular calcification: their relationship with diseases of the cardiovascular system and their importance in clinical practice

Атеросклероз, 2021
The literature review highlights the results of the most recent foreign and Russian studies on topical problems of vascular calcification with an emphasis on the relationship between some biochemical markers of vascular calcification (in priority ...
N. A. Maslatsov, Yu. I. Ragino
doaj   +1 more source

Osteocalcin Alleviates Nonalcoholic Fatty Liver Disease in Mice through GPRC6A

International Journal of Endocrinology, 2021
Osteocalcin is a bone-derived hormone that plays an important role in the crosstalk between bone and energy metabolism. Previous studies have found that treatment with uncarboxylated osteocalcin can protect mice from high-fat diet-induced nonalcoholic ...
Mingliang Zhang, Xiaomin Nie, Yeqing Yuan, Yansu Wang, Xiaojing Ma, Jun Yin, Yuqian Bao   +6 more
doaj   +1 more source