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Osteocalcin and Metabolic Syndrome
Clinical Medicine Insights: Endocrinology and Diabetes, 2023 Introduction: Metabolic syndrome which is a syndrome complex that is associated with insulin resistance. Osteocalcin (OC), a bone derived protein has been found to decrease insulin resistance and stimulate production of insulin from the pancreas. Serum osteocalcin levels correlate with body mass index (BMI) and waist circumference.
Aaditya Viswanath +2 more
openaire +3 more sources
Diabetology & Metabolic Syndrome, 2022 Background Osteocalcin, a protein secreted mainly by mature osteoblasts, has been shown to be involved in glucose metabolism through various pathways.
Jun Liu +12 more
doaj +1 more source
Interactions between Serum Adipokines and Osteocalcin in Older Patients with Hip Fracture
International Journal of Endocrinology, 2012 Introduction. Experiments on genetically modified animals have discovered a complex cross-regulation between adipokines (leptin, adiponectin) and osteocalcin. The relationships between these molecules in human osteoporosis are still unclear. We evaluated
Alexander Fisher +3 more
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Атеросклероз, 2021 The literature review highlights the results of the most recent foreign and Russian studies on topical problems of vascular calcification with an emphasis on the relationship between some biochemical markers of vascular calcification (in priority ...
N. A. Maslatsov, Yu. I. Ragino
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Osteocalcin Alleviates Nonalcoholic Fatty Liver Disease in Mice through GPRC6A
International Journal of Endocrinology, 2021 Osteocalcin is a bone-derived hormone that plays an important role in the crosstalk between bone and energy metabolism. Previous studies have found that treatment with uncarboxylated osteocalcin can protect mice from high-fat diet-induced nonalcoholic ...
Mingliang Zhang +6 more
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Metabolic Phenotypes and Step by Step Evolution of Type 2 Diabetes: A New Paradigm
Biomedicines, 2021 Unlike bolus insulin secretion mechanisms, basal insulin secretion is poorly understood. It is essential to elucidate these mechanisms in non-hyperinsulinaemia healthy persons.
Isabella D. Cooper +4 more
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Serum osteocalcin and bone mineral density in postmenopausal women
Universa Medicina, 2016 Since high bone turnover is associated with decreased bone mass, biochemical markers of bone remodeling, such as serum osteocalcin, may be used to assess osteoporosis and to predict fractures in elderly women, particulary those involving trabecular bone,
Lie T. Merijanti Susanto
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Effect of Obesity and Osteocalcin on Brain Glucose Metabolism in Healthy Participants
Brain Sciences, 2023 We evaluated the effects of obesity and osteocalcin on glucose metabolism in the brain. A total of 179 healthy men were enrolled in this study. After preprocessing positron emission tomography images, including by performing coregistration, spatial ...
Seunghyeon Shin, Hyun-Yeol Nam
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Evolution of Matrix Gla and Bone Gla Protein Genes in Jawed Vertebrates
Frontiers in Genetics, 2021 Matrix Gla protein (Mgp) and bone Gla protein (Bgp) are vitamin-K dependent proteins that bind calcium in their γ-carboxylated versions in mammals. They are recognized as positive (Bgp) or negative (Mgp and Bgp) regulators of biomineralization in a ...
Nicolas Leurs +4 more
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Sclerostin and Osteocalcin: Candidate Bone-Produced Hormones
Frontiers in Endocrinology, 2021 In addition to its structural role, the skeleton serves as an endocrine organ that controls mineral metabolism and energy homeostasis. Three major cell types in bone - osteoblasts, osteoclasts, and osteocytes – dynamically form and maintain bone and ...
Jialiang S. Wang +4 more
doaj +1 more source