Results 41 to 50 of about 79,934 (285)

Osteocalcin nodule formation in MSCs. [PDF]

open access: yes, 2018
(A) Representative MSC images from GNP treatment after 3 weeks. Staining indicates actin (green), nucleus (blue) and osteocalcin nodules (red). Scale bar = 5μm (white arrows highlights osteocalcin staining).
Pedro V. Baptista (2041387)   +5 more
core   +1 more source

Interactions between Serum Adipokines and Osteocalcin in Older Patients with Hip Fracture

open access: yesInternational Journal of Endocrinology, 2012
Introduction. Experiments on genetically modified animals have discovered a complex cross-regulation between adipokines (leptin, adiponectin) and osteocalcin. The relationships between these molecules in human osteoporosis are still unclear. We evaluated
Alexander Fisher   +3 more
doaj   +1 more source

Biomarkers of vascular calcification: their relationship with diseases of the cardiovascular system and their importance in clinical practice

open access: yesАтеросклероз, 2021
The literature review highlights the results of the most recent foreign and Russian studies on topical problems of vascular calcification with an emphasis on the relationship between some biochemical markers of vascular calcification (in priority ...
N. A. Maslatsov, Yu. I. Ragino
doaj   +1 more source

Osteocalcin gene polymorphisms influence concentration of serum osteocalcin and enhance fracture identification. [PDF]

open access: yes, 2010
Osteoporosis is a major health problem affecting more than 75 million people throughout Europe, USA and Japan. Epidemiological studies have determined that both genetic and environmental factors contribute to the pathogenesis of osteoporosis.
Gerdhem, Paul   +17 more
core   +3 more sources

Metabolic Phenotypes and Step by Step Evolution of Type 2 Diabetes: A New Paradigm

open access: yesBiomedicines, 2021
Unlike bolus insulin secretion mechanisms, basal insulin secretion is poorly understood. It is essential to elucidate these mechanisms in non-hyperinsulinaemia healthy persons.
Isabella D. Cooper   +4 more
doaj   +1 more source

An osteocalcin-deficient mouse strain without endocrine abnormalities

open access: yesbioRxiv, 2019
Osteocalcin (OCN), the most abundant non-collagenous protein in the bone matrix, is reported to be a bone-derived endocrine hormone with wide-ranging effects on many aspects of physiology, including glucose metabolism and male fertility.
Cassandra R Diegel   +14 more
semanticscholar   +1 more source

Deficiency of the bone mineralization inhibitor NPP1 protects against obesity and diabetes [PDF]

open access: yes, 2014
The emergence of bone as an endocrine regulator has prompted a re-evaluation of the role of bone mineralization factors in the development of metabolic disease.
Elspeth M. Milne   +27 more
core   +1 more source

Effect of Obesity and Osteocalcin on Brain Glucose Metabolism in Healthy Participants

open access: yesBrain Sciences, 2023
We evaluated the effects of obesity and osteocalcin on glucose metabolism in the brain. A total of 179 healthy men were enrolled in this study. After preprocessing positron emission tomography images, including by performing coregistration, spatial ...
Seunghyeon Shin, Hyun-Yeol Nam
doaj   +1 more source

Osteocalcin Mediates Biomineralization during Osteogenic Maturation in Human Mesenchymal Stromal Cells

open access: yesInternational Journal of Molecular Sciences, 2017
There is a growing interest in cell therapies using mesenchymal stromal cells (MSCs) for repairing bone defects. MSCs have the ability to differentiate into osteoprogenitors and osteoblasts as well as to form calcified bone matrix. However, the molecular
Yu‐Tzu Tsao   +5 more
semanticscholar   +1 more source

Osteocalcin improves outcome after acute ischemic stroke

open access: yesAging, 2020
Background: Osteocalcin is related to energy metabolism, memory and the acute stress response, suggesting a relationship between bone and the brain. The need to explore the effect of osteocalcin on acute ischemic stroke is therefore urgent.
Jiayan Wu   +4 more
semanticscholar   +1 more source

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