Results 111 to 120 of about 182,622 (382)
PLoS ONEOsteoclasts are crucial in the events leading to bone metastasis of lung cancer. Interleukin-17A (IL-17A) affects osteogenesis by regulating the survival of osteoclast precursors (OCPs) and is enriched in lung cancer cells.
Hongkai Wang +6 more
doaj +1 more source
The Osteoclast in Bone Metastasis: Player and Target
Cancers, 2018 Bone metastases are frequently the final fate of breast and prostate cancer patients. According to the definition of metastasis as an incurable disease, to date there are no effective treatments for tumor-associated bone metastases and this represents a ...
A. Maurizi, N. Rucci
semanticscholar +1 more source
The unbearable lightness of bone marrow homeostasis [PDF]
, 2015 The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS +3 more
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INTRAVASCULAR OSTEOCLASTS [PDF]
The Journal of Bone and Joint Surgery. British volume, 1957 1. In five out of eleven cases of osteoclastoma it was found that osteoclasts were present inside clearly defined blood vessels either within the tumours or in the tissues immediately surrounding the tumours. In two further cases it was found that osteoclasts protruded into the vessels although they were not lying free within the vessels. 2.
openaire +2 more sources
Advanced Functional Materials, EarlyView.Apatite occurs in many forms in nature, e.g. in teeth and geological minerals. Internally, biological apatite contains nanocrystals that are also found in synthetically prepared calcium phosphate nanoparticles which are used in biomedicine, e.g. for gene and drug delivery and for bone regeneration. Abstract Calcium phosphate is the inorganic component (
Kathrin Kostka +3 more
wiley +1 more source
Matrix-embedded cells control osteoclast formation
Nature Network Boston, 2011 Osteoclasts resorb the mineralized matrices formed by chondrocytes or osteoblasts. The cytokine receptor activator of nuclear factor-κB ligand (RANKL) is essential for osteoclast formation and thought to be supplied by osteoblasts or their precursors ...
J. Xiong +5 more
semanticscholar +1 more source
High Serum Concentration of Interleukine-6 and Rank-ligand as Risk Factors for Osteoporosis in Estrogen Deficiency Post-menopausal Women [PDF]
, 2009 Osteoporosis in post-menopausal women is not merely due to deficient estrogenhormone production. The development of osteoporosis is due to increased boneresorption by osteoclasts. The osteoclast\u27s number and activity is controlled by activatingfactors
Bakta, M. (Made) +3 more
core
Electron Microscopic Studying of Rat Bone Cells Under Microgravity Conditions [PDF]
, 2016 In the experiments on rats (SLS-2) with the use of electron microscopy there was made the study of the osteoclasts population and the peculiarities of resorptive processes in a spongy bone of the epiphyses and the iliac crest.The results of investigation
Polkovenko, O. (Olga)
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Advanced Healthcare Materials, EarlyView.This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret +4 more
wiley +1 more source
Bone ResearchEfficient cellular fusion of mononuclear precursors is the prerequisite for the generation of fully functional multinucleated bone-resorbing osteoclasts.
Brenda Krishnacoumar +20 more
doaj +1 more source