ABSTRACT Aim The purpose of this study was to compare the outcome of nonsurgical root canal treatment (RCT) in patients with autoimmune diseases (AD) with the outcome in patients without AD. The null hypothesis was: there is no difference in the outcomes of RCT regardless of the patient group. Results were also compared among AD subgroups: inflammatory
Seoyeon Lee +4 more
wiley +1 more source
LincRNA-EPS alleviates osteoclastogenesis under inflammatory microenvironment through preventing excessive iron metabolism. [PDF]
Wang J, Wang Y, Zhang Z, Wang X, Su J.
europepmc +1 more source
Multiple External Invasive Root Resorption and Calcification in Systemic Sclerosis—Case Report
ABSTRACT Aim There are few reports in the literature of multiple external invasive root resorption (EIRR) lesions in patients with systemic sclerosis (SSc), and an association between root resorption and SSc is not well established. We report the only case that comprehensively illustrates—with the combination of histopathology, cone beam computed ...
Jee‐Yun Leung +3 more
wiley +1 more source
SIRT1 Downregulation by Advanced Glycation End Products Activates RANKL-Dependent Osteoclast Signaling and Drives Chondrocyte Senescence During Osteoarthritis Development. [PDF]
Li Y, Wu J, Liu R, Li Q, Xue F.
europepmc +1 more source
The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli +3 more
wiley +1 more source
Clinical and Molecular Characterization of <i>TCIRG1</i>-Related Autosomal Recessive Osteopetrosis with Current Therapeutic Approaches. [PDF]
Nagieva SE, Smirnikhina SA.
europepmc +1 more source
Abstract Background Non‐ambulatory adults have an increased risk of osteoporosis and fractures due to reduced weight‐bearing and diminished neuromuscular stimulation, resulting in substantial morbidity and mortality. Aims This scoping review aimed to systematically evaluate risk factors, diagnostic indicators and management strategies for optimising ...
Thomas Bailey +4 more
wiley +1 more source
Role of Caffeine and Ethanol in Modulating Expression of Receptor Activator of Nuclear Factor κβ (RANK) and Osteoprotegerin (OPG) during Orthodontic Tooth Movement: An In Vivo Study. [PDF]
Pawinru AS +8 more
europepmc +1 more source
ABSTRACT Introduction This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug‐target database screening. Methods Proteomic analyses of saliva using LC–MS/MS were conducted in two independent settings: a cohort (sub‐study I, N = 187) and
Taisir Bozo +11 more
wiley +1 more source
Spectrum and functions of ion channels and transporters in osteoclasts. [PDF]
Chen H +5 more
europepmc +1 more source

