Results 211 to 220 of about 88,889 (259)

The IRE1-XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5-HT Dependent Endogenous Anti-Autophagy Mechanism. [PDF]

Adv Sci (Weinh)
Yang P, Zhu B, He Y, Tian Y, Kang H, Hu S, Wang P, Xu Y, Lei Z, Qi P, Yang H, Lin Y, Dong Y, Li F, Guan H.   +14 more
europepmc   +1 more source

Premature Occlusal Contacts Induce MRONJ in Osseointegrated Dental Implants: An Experimental In Vivo Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives Medication‐related osteonecrosis of the jaw (MRONJ) is a debilitating condition associated with antiresorptive agents (ARAs) and can occur around well‐osseointegrated dental implants. Although implant presence–triggered osteonecrosis (IPTO) has been primarily linked to bacteria‐related peri‐implantitis, whether occlusal trauma ...
Eun‐Bin Bae, Ahana Goswami, Jun Yaung, Soo Yeon Kim, Sherry S. Baik, Kaylyn A. Yu, Chan Park, Jung‐Bo Huh, Jae‐Young Kim, Christine Y. Hong, Sol Kim, Reuben H. Kim   +11 more
wiley   +1 more source

Runt-related transcription factor 2 transcriptionally represses sirtuin 1 to regulate osteoclastogenesis and tooth eruption. [PDF]

J Dent Sci
Li J, Yan C, Sun X, Zhang C, Wang X, Liu Y, Zheng S.   +6 more
europepmc   +1 more source

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

Reprogramming bone homeostasis: The recoupling-oriented framework of bidirectional regulation strategies for osteoporosis. [PDF]

iScience
Niu J, Li Z, Zou Y, Wang Z, Kang J, Zhang Y, Wang S, Liu R, Han X.   +8 more
europepmc   +1 more source

Withdrawn: Impact of the RNF123 mutation on osteoclast differentiation in familial ankylosing spondylitis

Rheumatology &Autoimmunity, EarlyView.
Jin S, Ji X, Zhang L, Shi Y, Zhao D, Wan W. Impact of the RNF123 mutation on osteoclast differentiation in familial ankylosing spondylitis. Rheumatol & Autoimmun. 2023;1‐8. doi:10.1002/rai2.12102 Withdrawal: The above article, first published online 11th September 2024, on Wiley Online Library (wileyonlinelibrary.com), has been withdrawn by agreement ...
wiley   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source

Antioxidant and Anti-Osteoclastogenic Potential of Olive Oil Dregs Extracts. [PDF]

Molecules
Castiglioni B, Squillaci G, Marchetti A, Imbimbo M, Perez-Barreto A, Morana A, Carbone V, Bosetti M.   +7 more
europepmc   +1 more source