Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley +1 more source
Optimizing <i>in vitro</i> osteoclastogenesis: bone marrow-derived macrophages differentiation and cell density as critical determinants. [PDF]
Li J +6 more
europepmc +1 more source
Intramuscular myxoma with chondroid features: two cases expanding the morphological spectrum
Background Intramuscular myxoma is a benign mesenchymal tumour typically composed of bland spindle to stellate cells in abundant myxoid stroma and usually characterized by GNAS mutations. Chondroid matrix has not been previously reported in intramuscular myxoma.
Bethany Batson +5 more
wiley +1 more source
TSP-1 interaction with RANK and OPG: implications for bone remodeling and osteolytic bone metastasis. [PDF]
Carminati L +9 more
europepmc +1 more source
Abstract Background The effect of tenofovir disoproxil fumarate (TDF) when used as pre‐exposure prophylaxis (PrEP) on renal function in pregnant and postpartum women is understudied. An open‐label clinical trial (CAP016 study) was designed to examine the safety of TDF‐PrEP use during pregnancy and breastfeeding.
Gaysheen Kistan +5 more
wiley +1 more source
Geranylgeraniol promotes osteoblast differentiation and inhibits osteoclastogenesis through MAPK and nuclear receptor signaling. [PDF]
Tomomura M +5 more
europepmc +1 more source
ABSTRACT Aim The purpose of this study was to compare the outcome of nonsurgical root canal treatment (RCT) in patients with autoimmune diseases (AD) with the outcome in patients without AD. The null hypothesis was: there is no difference in the outcomes of RCT regardless of the patient group. Results were also compared among AD subgroups: inflammatory
Seoyeon Lee +4 more
wiley +1 more source
Regenerative bone-targeted nanoparticles modulate osteoclast function.
Rangasami VK +3 more
europepmc +1 more source
VEGF-D-induced intraosseous lymphangiogenesis drives site-specific heterotopic bone resorption. [PDF]
Vishlaghi N +10 more
europepmc +1 more source

