Results 11 to 20 of about 210,118 (389)

Mechanical force induces macrophage-derived exosomal UCHL3 promoting bone marrow mesenchymal stem cell osteogenesis by targeting SMAD1

Journal of Nanobiotechnology, 2023
Background Orthodontic tooth movement (OTM), a process of alveolar bone remodelling, is induced by mechanical force and regulated by local inflammation. Bone marrow-derived mesenchymal stem cells (BMSCs) play a fundamental role in osteogenesis during OTM.
Panjun Pu, Shengnan Wu, Kejia Zhang, Hao Xu, Jiani Guan, Zhichun Jin, Wen Sun, Hanwen Zhang, Bin Yan   +8 more
doaj   +2 more sources

Lithium and Copper Induce the Osteogenesis-Angiogenesis Coupling of Bone Marrow Mesenchymal Stem Cells via Crosstalk between Canonical Wnt and HIF-1α Signaling Pathways

Stem Cells International, 2021
The combination of osteogenesis and angiogenesis dual-delivery trace element-carrying bioactive scaffolds and stem cells is a promising method for bone regeneration and repair.
Zhen Tan, Baochun Zhou, Jianrui Zheng, Yongcan Huang, Hui Zeng, Lixiang Xue, Deli Wang   +6 more
doaj   +2 more sources

Osteogenesis imperfecta

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2006
Osteogenesis imperfecta is an inherited disorder of the connective tissue. The extreme bone fragility seen in patients suffering from osteogenesis imperfecta pose a series of problems with regard to behavior management and rendering of quality dental ...
Gupte Tejashri, Iyer V, Damle S, Malik N, Halbe A   +4 more
doaj   +2 more sources

Impact of FasL Stimulation on Sclerostin Expression and Osteogenic Profile in IDG-SW3 Osteocytes

Biology, 2021
The Fas ligand (FasL) is known from programmed cell death, the immune system, and recently also from bone homeostasis. As such, Fas signalling is a potential target of anti-osteoporotic treatment based on the induction of osteoclastic cell death.
Adela Kratochvilova, Alice Ramesova, Barbora Vesela, Eva Svandova, Herve Lesot, Reinhard Gruber, Eva Matalova   +6 more
doaj   +1 more source

Regulation of Osteoimmune Microenvironment and Osteogenesis by 3D‐Printed PLAG/black Phosphorus Scaffolds for Bone Regeneration

Advancement of science, 2023
The treatment of bone defects remains a significant challenge to be solved clinically. Immunomodulatory properties of orthopedic biomaterials have significance in regulating osteoimmune microenvironment for osteogenesis.
J. Long, Zhenyu Yao, Wei Zhang, Ben Liu, Kaiming Chen, Long Li, Bin Teng, Xiangfu Du, Cairong Li, Xue‐Feng Yu, Ling Qin, Y. Lai   +11 more
semanticscholar   +1 more source

A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis

Nature, 2021
Stromal cells in adult bone marrow that express leptin receptor (LEPR) are a critical source of growth factors, including stem cell factor (SCF), for the maintenance of haematopoietic stem cells and early restricted progenitors1–6.
Bo Shen, Alpaslan Tasdogan, Jessalyn M. Ubellacker, Jingzhu Zhang, E. Nosyreva, Liming Du, M. Murphy, Shuiqing Hu, Yating Yi, Nergis Kara, Xin Liu, Shay Guela, Yuemeng Jia, V. Ramesh, Claire Embree, Evann C Mitchell, Y. Zhao, L. Ju, Zhao Hu, G. Crane, Zhiyu Zhao, Ruhma Syeda, S. Morrison   +22 more
semanticscholar   +1 more source

Novel scaffold platforms for simultaneous induction osteogenesis and angiogenesis in bone tissue engineering: a cutting-edge approach

Journal of Nanobiotechnology, 2023
Despite the recent advances in the development of bone graft substitutes, treatment of critical size bone defects continues to be a significant challenge, especially in the elderly population.
Arezoo Saberi, Maryam Kouhjani, Marzieh Mohammadi, Leticia Hosta-Rigau   +3 more
semanticscholar   +1 more source

Bone mesenchymal stem cells stimulation by magnetic nanoparticles and a static magnetic field: release of exosomal miR-1260a improves osteogenesis and angiogenesis

Journal of Nanobiotechnology, 2021
Background The therapeutic potential of exosomes derived from stem cells has attracted increasing interest recently, because they can exert similar paracrine functions of stem cells and overcome the limitations of stem cells transplantation.
Di Wu, Xiao-Ting Chang, Jingjing Tian, Lin Kang, Yuanhao Wu, Jieying Liu, Xiangdong Wu, Yue Huang, Bo Gao, Hai Wang, G. Qiu, Zhihong Wu   +11 more
semanticscholar   +1 more source

The patient clinical journey and socioeconomic impact of osteogenesis imperfecta: a systematic scoping review

Orphanet Journal of Rare Diseases, 2023
Background Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder primarily characterised by skeletal deformity and fragility, and an array of secondary features.
Maria Rapoport, Michael B. Bober, Cathleen Raggio, Lena Lande Wekre, Frank Rauch, Ingunn Westerheim, Tracy Hart, Taco van Welzenis, Arun Mistry, James Clancy, Lucy Booth, Samantha Prince, Oliver Semler   +12 more
doaj   +1 more source

Osteogenesis imperfecta

Indian Journal of Endocrinology and Metabolism, 2017
Osteogenesis imperfecta is a common heritable connective tissue disorder. Nearly ninety percent are due to Type I collagen mutations. Type I-IV are autosomal dominant, and Type VI-XIII are autosomal recessive. They are Graded 1-5 based on severity. Genomic testing is done by collagen analysis from fibroblasts.
Justin Easow Sam, Mala Dharmalingam
openaire   +6 more sources