Results 11 to 20 of about 195,947 (391)
Journal of Nanobiotechnology, 2021 Background The therapeutic potential of exosomes derived from stem cells has attracted increasing interest recently, because they can exert similar paracrine functions of stem cells and overcome the limitations of stem cells transplantation.
Di Wu +11 more
semanticscholar +1 more source
Orphanet Journal of Rare Diseases, 2023 Background Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder primarily characterised by skeletal deformity and fragility, and an array of secondary features.
Maria Rapoport +12 more
doaj +1 more source
International Journal on Biological Sciences, 2022 Irisin is well-known to contribute to bone homeostasis due to its bidirectional regulation on osteogenesis and osteoclastogenesis. However, the mechanisms of irisin involved in mesenchymal stem/stromal cells (MSCs)-derived osteogenesis are still under ...
Yuan Xue +9 more
semanticscholar +1 more source
The Mechanism of Pattern Transitions between Formation and Dispersion [PDF]
Journal of Theoretical Biology. 581, 111736 (2024), 2023 The patterns observed on the body surface of living organisms have traditionally been attributed solely to ecological strategies. However, this study investigates a fascinating phenomenon in Pelodiscus sinensis, where patterns formed on the plastron during embryonic and juvenile stages, which are not externally visible, ultimately disappear in ...
arxiv +1 more source
Frontiers in Endocrinology, 2022 Previous studies have revealed that melatonin could play a role in anti-osteoporosis and promoting osteogenesis. However, the effects of melatonin treatment on osteoporotic bone defect and the mechanism underlying the effects of melatonin on angiogenesis
S. Zheng +6 more
semanticscholar +1 more source
Regulation and Role of Transcription Factors in Osteogenesis
International Journal of Molecular Sciences, 2021 Bone is a dynamic tissue constantly responding to environmental changes such as nutritional and mechanical stress. Bone homeostasis in adult life is maintained through bone remodeling, a controlled and balanced process between bone-resorbing osteoclasts ...
W. C. Chan +3 more
semanticscholar +1 more source
Indian Journal of Endocrinology and Metabolism, 2017 Osteogenesis imperfecta is a common heritable connective tissue disorder. Nearly ninety percent are due to Type I collagen mutations. Type I-IV are autosomal dominant, and Type VI-XIII are autosomal recessive. They are Graded 1-5 based on severity. Genomic testing is done by collagen analysis from fibroblasts.
Justin Easow Sam, Mala Dharmalingam
openaire +6 more sources
Theranostics, 2021 Rationale: Emerging evidence indicates that the growth of blood vessels and osteogenesis is tightly coordinated during bone development. However, the molecular regulators of intercellular communication in the bone microenvironment are not well studied ...
J. Behera, Anil Kumar, M. Voor, N. Tyagi
semanticscholar +1 more source
The Human Gut Microbiota: A Key Mediator of Osteoporosis and Osteogenesis
International Journal of Molecular Sciences, 2021 An expanding body of research asserts that the gut microbiota has a role in bone metabolism and the pathogenesis of osteoporosis. This review considers the human gut microbiota composition and its role in osteoclastogenesis and the bone healing process ...
Kevin D. Seely +4 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2023 As the dentition forms and becomes functional, the alveolar bone is remodelled. Metalloproteinases are known to contribute to this process, but new regulators are emerging and their contextualization is challenging.
S. Varadinkova +11 more
doaj +1 more source