Results 31 to 40 of about 109,635 (268)
Frontiers in Cell and Developmental Biology, 2021 Osteogenesis imperfecta is a genetic disorder disrupting bone development and remodeling. The primary causes of osteogenesis imperfecta are pathogenic variants of collagen and collagen processing genes.
Christopher L. Schwebach +2 more
doaj +1 more source
Alveolar distraction osteogenesis: Archwise appliance and technique
, 2015 This book describes a new method of alveolar distraction osteogenesis that offers important advantages and can be used for the treatment of various orthopedic abnormalities and congenital malformations.
core +1 more source
Osteogenesis imperfecta and keratoconus in an Italian family [PDF]
, 2018 Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue involving genes encoding the synthesis of type 1 collagen.[1] Its clinical presentation can vary widely and may include blue scleras (Figure 1), bone fractures, the patient being ...
Peter G Swann +5 more
core +1 more source
Bleeding assessment in a large cohort of patients with Osteogenesis Imperfecta
Orphanet Journal of Rare DiseasesBackground Osteogenesis Imperfecta (OI) is characterised by bone fragility. Among several features, easy bruising and multiple case reports on haemorrhagic events have been reported.
Koert Gooijer +5 more
doaj +1 more source
Reversible Tuning of Multiple Molecular Kinking for Stem Cell Regulation In Vivo
Advanced Functional Materials, EarlyView.In this work, we introduce the novel concept of background component‐free “multiple kinks” material platform composed solely of liganded multiple kink‐bearing molecules as a strategy for dynamic biomaterial design. Tri‐kink molecules enable effective near‐infrared light‐triggered ligand masking and visible light‐triggered ligand exposure, thereby ...
Kanghyeon Kim +28 more
wiley +1 more source
Pan African Medical Journal, 2021 Osteogenesis imperfecta is a rare hereditary connective tissue disorder that affects the bones fragility. It causes the bones to break easily. The defective gene affects the body mechanism to form collagen, which strengthens the bone. A 20-year-old male patient came with complaints of pain in the left leg since morning.
Surya Besant Natarajan +1 more
openaire +3 more sources
Students with Osteogenesis Imperfecta: A Comparative Intergenerational Study of Inclusive Participation in New Zealand schools. [PDF]
, 2007 Osteogenesis imperfecta (OI) is a genetic condition commonly known as Brittle Bones. The purpose of this study was to listen to and document the experiences of those with OI to investigate if there were barriers to inclusive education for students with ...
Holmes, Heather Jeanette
core
Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Orphanet Journal of Rare DiseasesAdults with childhood-onset rare disease face many challenges when transitioning from pediatric services to adult care. While they often received specialized pediatric care, the adult healthcare system provides few resources for those whose rare disease ...
Laura L. Tosi +4 more
doaj +1 more source
How is Nanoarchitectonics Shaping Extracellular Vesicle Research?
Advanced Healthcare Materials, EarlyView.The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake +5 more
wiley +1 more source