Results 11 to 20 of about 165,191 (338)

Osteogenesis Imperfecta [PDF]

Nature Reviews Disease Primers, 2017
Osteogenesis imperfecta is a common heritable connective tissue disorder. Nearly ninety percent are due to Type I collagen mutations. Type I-IV are autosomal dominant, and Type VI-XIII are autosomal recessive. They are Graded 1-5 based on severity. Genomic testing is done by collagen analysis from fibroblasts.
Nicholas Bishop, Peter H. Byers, Deborah Krakow   +2 more
exaly   +11 more sources

Osteogenesis imperfecta

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2006
Osteogenesis imperfecta is an inherited disorder of the connective tissue. The extreme bone fragility seen in patients suffering from osteogenesis imperfecta pose a series of problems with regard to behavior management and rendering of quality dental ...
Gupte Tejashri, Iyer V, Damle S, Malik N, Halbe A   +4 more
doaj   +3 more sources

Mitochondrial Fragmentation and Donut Formation Enhance Mitochondrial Secretion to Promote Osteogenesis

Cell Metabolism, 2023
Mitochondrial components have been abundantly detected in bone matrix, implying that they are somehow transported extracellularly to regulate osteogenesis. Here, we demonstrate that mitochondria and mitochondrial-derived vesicles (MDVs) are secreted from
Yun-Sil Lee, Jung-Eun Kim
exaly   +2 more sources

Mechanical force induces macrophage-derived exosomal UCHL3 promoting bone marrow mesenchymal stem cell osteogenesis by targeting SMAD1

Journal of Nanobiotechnology, 2023
Background Orthodontic tooth movement (OTM), a process of alveolar bone remodelling, is induced by mechanical force and regulated by local inflammation. Bone marrow-derived mesenchymal stem cells (BMSCs) play a fundamental role in osteogenesis during OTM.
Panjun Pu, Shengnan Wu, Kejia Zhang, Hao Xu, Jiani Guan, Zhichun Jin, Wen Sun, Hanwen Zhang, Bin Yan   +8 more
doaj   +2 more sources

OSTEOGENESIS DAN TUMBUH-KEMBANG SKELET KRANIOFASIAL MANUSIA

Journal of Dentistry Indonesia, 2015
Osteogenesis depends on the original cells, which are indirect or endochondral osteogenesis, and direct or intramembranous osteogenesis. The skeletal of craniofacial consist of bones, group of bones, and cartilages.
Sarworini Bagio Budiardjo
doaj   +2 more sources

Osteogenesis imperfecta and potential therapies [PDF]

Journal of Education, Health and Sport, 2022
Background: Osteogenesis imperfecta (OI) is a genetically determined disorder of connective tissue. In this article we reviewed epidemiology, types of OI, pathophysiology, symptoms and potential therapies.
Mateusz Fabis, Klaudia Remjasz, Julia Kuchnicka, Wojciech Siedlecki, Jakub Aleksandrowicz, Bartłomiej Wójcik, Karolina Zadrożna   +6 more
doaj   +2 more sources

Ca2+-Supplying Black Phosphorus-Based Scaffolds Fabricated With Microfluidic Technology for Osteogenesis

Bioactive Materials, 2021
Effective osteogenesis remains a challenge in the treatment of bone defects. The emergence of artificial bone scaffolds provides an attractive solution.
Xingcai Zhang, Grace X Gu, Lin Jin
exaly   +2 more sources

Endothelial cell-derived exosomes trigger a positive feedback loop in osteogenesis-angiogenesis coupling via up-regulating zinc finger and BTB domain containing 16 in bone marrow mesenchymal stem cell

Journal of Nanobiotechnology
The close spatial and temporal connection between osteogenesis and angiogenesis around type H vasculature is referred as “osteogenesis-angiogenesis coupling”, which is one of the basic mechanisms of osteogenesis.
Lu Liu, Nan Zhou, Songning Fu, Linlin Wang, Yadong Liu, Changfeng Fu, Feng Xu, Weiying Guo, Yanhua Wu, Jin Cheng, Jun Dai, Yipeng Wang, Xiaofeng Wang, Qiwei Yang, Yuanyi Wang   +14 more
doaj   +2 more sources

Biofunctional Magnesium Coated Ti6Al4V Scaffold Enhances Osteogenesis and Angiogenesis in Vitro and in Vivo for Orthopedic Application

Bioactive Materials, 2020
The insufficient osteogenesis and osseointegration of porous titanium based scaffold limit its further application. Early angiogenesis is important for scaffold survival. It is necessary to develop a multifunctional surface on titanium scaffold with both
Lei Shi, Wenwen Liu, Zheng Guo
exaly   +2 more sources

Mechanical stretch promotes osteogenesis in the midpalatal suture by enhancing neutrophil fatty acid oxidation through the S1PR1/STAT3 axis [PDF]

Mechanobiology in Medicine
In clinical maxillary arch constriction, selecting an optimal initial distraction force may help reduce relapse associated with insufficient suture osteogenesis.
Ting Jiang, Tian-Hao Wan, Min-Jie Wang, Xin-Yi Tan, Zhi-Chen Ling, Feng Yang, Jun Wang, Ning-Juan Ouyang   +7 more
doaj   +2 more sources