Results 21 to 30 of about 210,118 (389)

In Vitro and In Vivo Applications of Magnesium-Enriched Biomaterials for Vascularized Osteogenesis in Bone Tissue Engineering: A Review of Literature

open access: yesJournal of Functional Biomaterials, 2023
Bone is a highly vascularized tissue, and the ability of magnesium (Mg) to promote osteogenesis and angiogenesis has been widely studied. The aim of bone tissue engineering is to repair bone tissue defects and restore its normal function.
Jiewei Hu   +4 more
semanticscholar   +1 more source

Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]

open access: yes, 2020
Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A.   +2 more
core   +1 more source

Regulation and Role of Transcription Factors in Osteogenesis

open access: yesInternational Journal of Molecular Sciences, 2021
Bone is a dynamic tissue constantly responding to environmental changes such as nutritional and mechanical stress. Bone homeostasis in adult life is maintained through bone remodeling, a controlled and balanced process between bone-resorbing osteoclasts ...
W. C. Chan   +3 more
semanticscholar   +1 more source

Fatigue in adults with Osteogenesis Imperfecta

open access: yesBMC Musculoskeletal Disorders, 2020
Background Osteogenesis Imperfecta (OI) is characterized by bone fragility, and features such as blue sclerae, dentinogenesis imperfecta, hearing loss, ligamentous laxity and short stature can be present.
Arjan G. J. Harsevoort   +6 more
doaj   +1 more source

Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor

open access: yesFrontiers in Cell and Developmental Biology, 2023
As the dentition forms and becomes functional, the alveolar bone is remodelled. Metalloproteinases are known to contribute to this process, but new regulators are emerging and their contextualization is challenging.
S. Varadinkova   +11 more
doaj   +1 more source

“Osteogenesis Imperfecta Patients Wish Orthopedic Surgeons Had Better Strategies to Help with…”—Results of a Patient and Parent-Oriented Survey

open access: yesChildren, 2023
Osteogenesis Imperfecta (OI) is a rare genetic disorder in Type I collagen characterized by bone fractures, fragility, and deformity. Current treatments are focused on decreasing fracture rates, improving bone strength, and improving overall global ...
Jill Flanagan   +5 more
doaj   +1 more source

Exosomal lncRNA-H19 promotes osteogenesis and angiogenesis through mediating Angpt1/Tie2-NO signaling in CBS-heterozygous mice

open access: yesTheranostics, 2021
Rationale: Emerging evidence indicates that the growth of blood vessels and osteogenesis is tightly coordinated during bone development. However, the molecular regulators of intercellular communication in the bone microenvironment are not well studied ...
Jyotirmaya Behera   +3 more
semanticscholar   +1 more source

Formation and Developmental Specification of the Odontogenic and Osteogenic Mesenchymes

open access: yesFrontiers in Cell and Developmental Biology, 2020
Within the mandible, the odontogenic and osteogenic mesenchymes develop in a close proximity and form at about the same time. They both originate from the cranial neural crest. These two condensing ecto-mesenchymes are soon separated from each other by a
Eva Svandova   +4 more
doaj   +1 more source

Myokine Irisin promotes osteogenesis by activating BMP/SMAD signaling via αV integrin and regulates bone mass in mice

open access: yesInternational Journal on Biological Sciences, 2022
Irisin is well-known to contribute to bone homeostasis due to its bidirectional regulation on osteogenesis and osteoclastogenesis. However, the mechanisms of irisin involved in mesenchymal stem/stromal cells (MSCs)-derived osteogenesis are still under ...
Yuan Xue   +9 more
semanticscholar   +1 more source

Melatonin Accelerates Osteoporotic Bone Defect Repair by Promoting Osteogenesis–Angiogenesis Coupling

open access: yesFrontiers in Endocrinology, 2022
Previous studies have revealed that melatonin could play a role in anti-osteoporosis and promoting osteogenesis. However, the effects of melatonin treatment on osteoporotic bone defect and the mechanism underlying the effects of melatonin on angiogenesis
Sheng Zheng   +6 more
semanticscholar   +1 more source

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