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Alterations in Immunomodulatory Potential of ADSCs Undergoing Osteogenic Differentiation in the Context of Future Therapeutic Applications. [PDF]
CellsSzabłowska-Gadomska I +6 more
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Exosome-functionalized alginate/gelatin composite scaffolds: synergistic enhancement of osteogenic differentiation for bone tissue engineering. [PDF]
J Orthop Surg ResMeskaraf-Asadabadi M +4 more
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Osteogenic Sarcoma with Epithelial Differentiation
Ultrastructural Pathology, 1992This case report details an osteogenic sarcoma arising in a vertebra in which cytokeratin intermediate filaments were detected immunohistochemically with three different antibodies. This feature was present not only in the primary neoplasm but also in two local recurrences and a metastasis to the iliac bone. What is unique about this primary bone tumor,
I, Dardick, J E, Schatz, T J, Colgan
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Laminins in osteogenic differentiation and pluripotency maintenance
Differentiation, 2020Extracellular matrix (ECM) plays an integral role in different developmental stages and in multiple systems. However, due to ECM being composed of various extracellular components (growth factors, cytokines, and hormones), its innate complexity and the lack of any efficient purification techniques limit further research into the detailed mechanisms of ...
Chaozhen Chen, Zhiwei Jiang, Guoli Yang
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Role of MT1-MMP in the osteogenic differentiation
Bone, 2009Metalloproteinase MT1-MMP is induced and Pro-MMP-2 up modulated early in rat preosteoblasts (ROB) set to differentiate. We here show that the induction of MMPs, accompanied by activation of Pro-MMP-2, occurs by 6 h of adhesion on endogenous extracellular matrix (ECM), Fibronectin (FN) and Collagen type I (CI).
Manduca P +9 more
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Epigenetic modifications in osteogenic differentiation and transformation
Journal of Cellular Biochemistry, 2006AbstractAlmost all tumors are characterized by both architectural and cellular abnormalities in differentiation. Osteoblast development is relatively well understood, making osteosarcoma a good model for understanding how tumorigenesis perturbs normal differentiation.
David, Thomas, Maya, Kansara
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In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells
Biomaterials, 1997The process of ectopic bone formation suggests that extraskeletal cells are capable of osteogenesis. Alkaline phosphatase (ALP) activity is considered to be an early marker of osteogenic differentiation. This study determined whether cells from the rabbit dermis, striated muscle and extramedullary adipose tissue could undergo osteogenic differentiation
L, Lecoeur, J P, Ouhayoun
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Potential for Osteogenic and Chondrogenic Differentiation of MSC
2012The introduction of mesenchymal stem cells (MSC) into the field of tissue engineering for bone and cartilage repair is a promising development, since these cells can be expanded ex vivo to clinically relevant numbers and, after expansion, retain their ability to differentiate into different cell lineages.
Antonina, Lavrentieva +4 more
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Osteogenic differentiation on DLC‐PDMS‐h surface
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014AbstractThe hypothesis was that anti‐fouling diamond‐like carbon polydimethylsiloxane hybrid (DLC‐PDMS‐h) surface impairs early and late cellular adhesion and matrix–cell interactions. The effect of hybrid surface on cellular adhesion and cytoskeletal organization, important for osteogenesis of human mesenchymal stromal cells (hMSC), where therefore ...
Kaivosoja Emilia +12 more
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