Results 271 to 280 of about 139,682 (311)

Osteogenic Differentiation from Mouse Embryonic Stem Cells

2021
Embryonic stem cells (ESCs) are a unique model that allows the study of molecular pathways underlying commitment and differentiation. We have studied signaling pathways and their contributions to osteogenic differentiation. In addition to our previously published protocol where we recommended the addition of retinoic acid with later addition of ...
Zahra, Alvandi, Michal, Opas
openaire   +2 more sources

Osteogenic differentiation on DLC‐PDMS‐h surface

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014
AbstractThe hypothesis was that anti‐fouling diamond‐like carbon polydimethylsiloxane hybrid (DLC‐PDMS‐h) surface impairs early and late cellular adhesion and matrix–cell interactions. The effect of hybrid surface on cellular adhesion and cytoskeletal organization, important for osteogenesis of human mesenchymal stromal cells (hMSC), where therefore ...
Kaivosoja Emilia, Soininen Antti, Kaivosoja Emilia, Sillat Tarvo, Tiainen Veli-Matti, Konttinen Yrjo T., Soininen Antti, Kaivosoja Emilia, Sillat Tarvo, Tiainen Veli-Matti, Konttinen Yrjo T., Konttinen Yrjö   +11 more
openaire   +5 more sources

Engineered Phage Matrix Stiffness-Modulating Osteogenic Differentiation

ACS Applied Materials & Interfaces, 2018
Herein, we demonstrate an engineered phage mediated matrix for osteogenic differentiation with controlled stiffness by cross-linking the engineered phage displaying Arg-Gly-Asp (RGD) and His-Pro-Gln (HPQ) with various concentrations of streptavidin or polymer, poly(diallyldimethylammonium)chloride (PDDA).
Hee-Sook Lee, Jeong-In Kang, Woo-Jae Chung, Do Hoon Lee, Byung Yang Lee, Seung-Wuk Lee, So Young Yoo   +6 more
openaire   +2 more sources

Osteogenic Differentiation from Embryonic Stem Cells

2014
Embryonic stem (ES) cells have been widely studied due to their pluripotency and their potential of self-renewal. Murine ES cells are useful in investigating the molecular pathways underlying their differentiation to various mature cell types in the body.
Yanhong, Yu, Carlos, Pilquil, Michal, Opas   +2 more
openaire   +2 more sources

Laminins in osteogenic differentiation and pluripotency maintenance

Differentiation, 2020
Extracellular matrix (ECM) plays an integral role in different developmental stages and in multiple systems. However, due to ECM being composed of various extracellular components (growth factors, cytokines, and hormones), its innate complexity and the lack of any efficient purification techniques limit further research into the detailed mechanisms of ...
Chaozhen Chen, Zhiwei Jiang, Guoli Yang
openaire   +2 more sources

Osteogenic differentiation of intact human amniotic membrane

Biomaterials, 2010
Tissue engineering strategies usually require cell isolation and combination with a suitable biomaterial. Human amniotic membrane (AM) represents a natural two-layered sheet comprising cells with proven stem cell characteristics. In our approach, we evaluated the differentiation potential of AM in toto with its sessile stem cells as alternative to ...
Lindenmair, Andrea, Wolbank, Susanne, Stadler, Guido, Meinl, Alexandra, Peterbauer-Scherb, Anja, Eibl, Johann, Polin, Helene, Gabriel, Christian, van Griensven, Martijn, Redl, Heinz   +9 more
openaire   +3 more sources

Epigenetic modifications in osteogenic differentiation and transformation

Journal of Cellular Biochemistry, 2006
AbstractAlmost all tumors are characterized by both architectural and cellular abnormalities in differentiation. Osteoblast development is relatively well understood, making osteosarcoma a good model for understanding how tumorigenesis perturbs normal differentiation.
David, Thomas, Maya, Kansara
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Regulation of osteogenic differentiation during skeletal development

Frontiers in Bioscience, 2008
Bone formation during skeletal development involves a complex coordination among multiple cell types and tissues. Bone is of crucial importance for the human body, providing skeletal support, and serving as a home for the formation of hematopoietic cells and as a reservoir for calcium and phosphate.
Zhong-Liang, Deng, Katie A, Sharff, Ni, Tang, Wen-Xin, Song, Jinyong, Luo, Xiaoji, Luo, Jin, Chen, Erwin, Bennett, Russell, Reid, David, Manning, Anita, Xue, Anthony G, Montag, Hue H, Luu, Rex C, Haydon, Tong-Chuan, He   +14 more
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SIRT2 Mediated Microtubule Acetylation in Osteogenic Differentiation.

The Chinese journal of dental research
To assess the role of microtubule acetylation in the transportation of amorphous calcium phosphate (ACP)-containing vesicles that mediate the osteogenic differentiation process of rat bone mesenchymal stem cells (BMSCs).Rat BMSCs were cultured and transfected with sirtuin 2 (SIRT2) overexpression plasmids for an in vitro model.
Xin Ru, Zhou, Can, Zhang, Chen Rong, Xu, Xin Er, Tan, Qian Qian, Han, Xi, Yang, Tian Yu, Sun, Long Quan, Shao, Jia, Liu   +8 more
openaire   +2 more sources

[Kcnq1ot1 promotes osteogenic differentiation and suppresses osteoclast differentiation].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021
To investigate the regulatory role of long non-coding RNA Kcnq1ot1 in osteoclast differentiation, osteogenic differentiation and osteoporosis.The expression of lnc-Kcnq1ot1, Bglap, Runx2, Alp, Bsp, Nfatc1, Mmp9, Ctsk and Oscar were detected by real-time quantitative PCR (qRT-PCR) in the femoral bones from mouse models of postmenopausal osteoporosis ...
Kun, Zhang, Zhemin, Shi, Yi, Ren, Xiaohui, Han, Jingzhao, Wang, Wei, Hong   +5 more
openaire   +1 more source