Results 271 to 280 of about 91,170 (312)

Maqui berry cystatin inhibits cathepsin k activity and stimulates osteogenic differentiation of human dental pulp cells. [PDF]

J Appl Oral Sci
Silva LRD, Souza EP, Mendes BR, Amancio BH, Henrique-Silva F, Faria G.   +5 more
europepmc   +1 more source

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In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells

Biomaterials, 1997
The process of ectopic bone formation suggests that extraskeletal cells are capable of osteogenesis. Alkaline phosphatase (ALP) activity is considered to be an early marker of osteogenic differentiation. This study determined whether cells from the rabbit dermis, striated muscle and extramedullary adipose tissue could undergo osteogenic differentiation
J P Ouhayoun
exaly   +3 more sources

Osteogenic Sarcoma with Epithelial Differentiation

Ultrastructural Pathology, 1992
This case report details an osteogenic sarcoma arising in a vertebra in which cytokeratin intermediate filaments were detected immunohistochemically with three different antibodies. This feature was present not only in the primary neoplasm but also in two local recurrences and a metastasis to the iliac bone. What is unique about this primary bone tumor,
I, Dardick, J E, Schatz, T J, Colgan
openaire   +2 more sources

Laminins in osteogenic differentiation and pluripotency maintenance

Differentiation, 2020
Extracellular matrix (ECM) plays an integral role in different developmental stages and in multiple systems. However, due to ECM being composed of various extracellular components (growth factors, cytokines, and hormones), its innate complexity and the lack of any efficient purification techniques limit further research into the detailed mechanisms of ...
Chaozhen Chen, Zhiwei Jiang, Guoli Yang
openaire   +2 more sources

Roles of circular RNAs in osteogenic/osteoclastogenic differentiation

BioFactors, 2023
AbstractThe process of bone remodeling occurs and is regulated through interactions between osteoclasts, which resorb bone, and osteoblasts, which generate bone tissue. When the homeostatic balance between these two cell types is dysregulated, this can contribute to abnormal bone remodeling resulting in a loss of bone mass as is observed in ...
Tao Wang, Chao Zhang, Lin Xu, Xingnuan Li   +3 more
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Role of MT1-MMP in the osteogenic differentiation

Bone, 2009
Metalloproteinase MT1-MMP is induced and Pro-MMP-2 up modulated early in rat preosteoblasts (ROB) set to differentiate. We here show that the induction of MMPs, accompanied by activation of Pro-MMP-2, occurs by 6 h of adhesion on endogenous extracellular matrix (ECM), Fibronectin (FN) and Collagen type I (CI).
Manduca P, CASTAGNINO, ALESSIA, Lombardini D, Marchisio S, Soldano S, ULIVI, VALENTINA, Zanotti S, Garbi C, Ferrari N, PALMIERI, DANIELA   +9 more
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Effects of different physical factors on osteogenic differentiation

Biochimie, 2023
Osteoblasts are essential for bone formation and can perceive external mechanical stimuli, which are translated into biochemical responses that ultimately alter cell phenotypes and respond to environmental stimuli, described as mechanical transduction.
Li, Peng, Fanzi, Wu, Mengjiao, Cao, Mengxin, Li, Jingyao, Cui, Lijia, Liu, Yun, Zhao, Jing, Yang   +7 more
openaire   +2 more sources

Epigenetic modifications in osteogenic differentiation and transformation

Journal of Cellular Biochemistry, 2006
AbstractAlmost all tumors are characterized by both architectural and cellular abnormalities in differentiation. Osteoblast development is relatively well understood, making osteosarcoma a good model for understanding how tumorigenesis perturbs normal differentiation.
David, Thomas, Maya, Kansara
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Osteogenic differentiation on DLC‐PDMS‐h surface

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014
AbstractThe hypothesis was that anti‐fouling diamond‐like carbon polydimethylsiloxane hybrid (DLC‐PDMS‐h) surface impairs early and late cellular adhesion and matrix–cell interactions. The effect of hybrid surface on cellular adhesion and cytoskeletal organization, important for osteogenesis of human mesenchymal stromal cells (hMSC), where therefore ...
Kaivosoja Emilia, Soininen Antti, Kaivosoja Emilia, Sillat Tarvo, Tiainen Veli-Matti, Konttinen Yrjo T., Konttinen Yrjö, Soininen Antti, Kaivosoja Emilia, Sillat Tarvo, Tiainen Veli-Matti, Konttinen Yrjo T.   +11 more
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Potential for Osteogenic and Chondrogenic Differentiation of MSC

2012
The introduction of mesenchymal stem cells (MSC) into the field of tissue engineering for bone and cartilage repair is a promising development, since these cells can be expanded ex vivo to clinically relevant numbers and, after expansion, retain their ability to differentiate into different cell lineages.
Antonina, Lavrentieva, Tim, Hatlapatka, Anne, Neumann, Birgit, Weyand, Cornelia, Kasper   +4 more
openaire   +2 more sources