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Induction of Osteogenic Differentiation by Nanostructured Alumina Surfaces

Journal of Biomedical Nanotechnology, 2014
Permanent orthopedic implants are becoming increasingly important due to the demographic development. Their optimal osseointegration is key in obtaining good secondary stability. For anchorage dependent cells, topographic features of a surface play an essential role for cell adhesion, proliferation, differentiation and biomineralization. We studied the
Metzger, Wolfgang   +13 more
openaire   +3 more sources

Effects of PRP and LyPRP on osteogenic differentiation of MSCs

Journal of Biomedical Materials Research Part A, 2019
AbstractPlatelet‐rich plasma (PRP) is rich in a variety of growth factors and plays an important role in the proliferation and differentiation of mesenchymal stem cells (MSCs). It has been reported that the preparation of freeze‐dried platelets (lyophilized platelets [LyPRP]) from platelets could be an effective strategy to preserve the bioactivity of ...
Yuxing, Xie   +7 more
openaire   +2 more sources

Regulation of osteogenic differentiation during skeletal development

Frontiers in Bioscience, 2008
Bone formation during skeletal development involves a complex coordination among multiple cell types and tissues. Bone is of crucial importance for the human body, providing skeletal support, and serving as a home for the formation of hematopoietic cells and as a reservoir for calcium and phosphate.
Zhong-Liang, Deng   +14 more
openaire   +2 more sources

Osteogenic differentiation of intact human amniotic membrane

Biomaterials, 2010
Tissue engineering strategies usually require cell isolation and combination with a suitable biomaterial. Human amniotic membrane (AM) represents a natural two-layered sheet comprising cells with proven stem cell characteristics. In our approach, we evaluated the differentiation potential of AM in toto with its sessile stem cells as alternative to ...
Andrea, Lindenmair   +9 more
openaire   +2 more sources

Berberine derivative, Q8, stimulates osteogenic differentiation

Biochemical and Biophysical Research Communications, 2018
Berberine has been implicated to be involved in maintaining bone health due to its anti-oxidative and osteogenic properties. However, low potency and low bioavailability limit the clinical development of the drug. To overcome these obstacles, we previously synthesized a compound, Q8, which is a structural homolog of berberine.
Younho Han   +2 more
openaire   +2 more sources

Osteogenic and sarcomatoid differentiation of a renal cell carcinoma

Cancer, 1985
Sarcomatoid renal cell carcinoma is an uncommon renal tumor, and osteogenic differentiation has been reported in only a few of these tumors. The authors report such a case with radiographic, light microscopic, and electron microscopic findings, which demonstrate that the sarcomatoid areas of the tumor are derived from the malignant epithelial cells ...
R A, Macke   +4 more
openaire   +2 more sources

Regulating Osteogenic Differentiation by Suppression of Exosomal MicroRNAs

Tissue Engineering Part A, 2019
We investigated the role of exosomes in osteogenesis and the use of miRNA inhibitor-transfected exosomes to control osteogenic differentiation. RNA-sequencing (RNA-seq) of exosomal miRNAs revealed that growth condition of milieu of preosteoblast exosomes harbors high levels of let-7, which plays a critical role in osteogenesis regulation.
Song-Yi, Choi   +5 more
openaire   +2 more sources

[Differentiation of osteogenic cells in culture].

Tsitologiia, 2000
The regulatory factors and cell responses during osteogenic differentiation have been reviewed. Evidence has been provided on hormone and mechanical regulation and on the extracellular matrix (ECM). The data on responses of primary cell culture and constant cell lines of osteogenic origin to these regulations are represented in the number of tables. It
L A, Sadof'ev, O I, Podgornaia
openaire   +1 more source

Osteogenic Differentiation from Embryonic Stem Cells

2014
Embryonic stem (ES) cells have been widely studied due to their pluripotency and their potential of self-renewal. Murine ES cells are useful in investigating the molecular pathways underlying their differentiation to various mature cell types in the body.
Yanhong, Yu   +2 more
openaire   +2 more sources

SIRT2 Mediated Microtubule Acetylation in Osteogenic Differentiation.

The Chinese journal of dental research
To assess the role of microtubule acetylation in the transportation of amorphous calcium phosphate (ACP)-containing vesicles that mediate the osteogenic differentiation process of rat bone mesenchymal stem cells (BMSCs).Rat BMSCs were cultured and transfected with sirtuin 2 (SIRT2) overexpression plasmids for an in vitro model.
Xin Ru, Zhou   +8 more
openaire   +2 more sources

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