Results 111 to 120 of about 70,099 (277)

CYP2C8 gene polymorphism and bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma

open access: yesHaematologica, 2011
Osteonecrosis of the jaw is an uncommon but potentially serious complication of bisphosphonate therapy in multiple myeloma. Previous studies showed that the presence of one or two minor alleles of the cytochrome P450, subfamily 2C polypeptide 8 gene ...
Esperanza Such   +13 more
doaj   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

open access: yesJournal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa   +5 more
wiley   +1 more source

Osteonecrosis in a Patient with Crohn's Disease Unrelated to Corticosteroid Use

open access: yesCanadian Journal of Gastroenterology, 2001
Osteonecrosis is a feared complication of corticosteroid use. However, a direct association between corticosteroid use and osteonecrosis has never been proven.
Ali Khan   +3 more
doaj   +1 more source

Effect of metformin on inflammation and bone damage in a rat model of medication-related osteonecrosis of the jaw. [PDF]

open access: yesEur J Oral Sci
Abstract This study investigated how chronic metformin administration modulates the cellular profile and inflammatory markers in a zoledronic acid‐based rat model of medication‐related osteonecrosis of the jaw (MRONJ). Male Wistar rats were allocated to different treatments: (i) naïve, (ii) MRONJ (zoledronic acid, 0.2 mg/kg, i.v.
Rabelo LMA   +10 more
europepmc   +2 more sources

Differentially Expressed Salivary miRNAs in Temporomandibular Disorders

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Temporomandibular disorders (TMDs) are heterogeneous conditions of unclear aetiology involving the temporomandibular joint, masticatory muscles and neural tissues. Limited understanding of their pathogenesis hampers accurate diagnosis and targeted treatment. Therefore, this study aimed to identify salivary microRNA (miRNA) signatures
Karolina Elżbieta Kaczor‐Urbanowicz   +13 more
wiley   +1 more source

The multifaceted roles of extracellular vesicles in osteonecrosis of the femoral head

open access: yesJournal of Orthopaedic Translation
Osteonecrosis of the femoral head (ONFH) is a severe disease characterized by bone tissue necrosis due to vascular impairment, often leading to joint collapse and requiring surgical intervention. Extracellular vesicles (EVs) serve as crucial mediators of
Hongxu Li   +5 more
doaj   +1 more source

Stem cell therapy for osteonecrosis of femoral head: Opportunities and challenges

open access: gold, 2020
Yingxing Xu   +5 more
openalex   +1 more source

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du   +8 more
wiley   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

open access: yesOral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier   +6 more
wiley   +1 more source

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