Results 1 to 10 of about 22,928 (253)
CYP2C8 gene polymorphism and bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma [PDF]
Haematologica, 2011 Osteonecrosis of the jaw is an uncommon but potentially serious complication of bisphosphonate therapy in multiple myeloma. Previous studies showed that the presence of one or two minor alleles of the cytochrome P450, subfamily 2C polypeptide 8 gene ...
Esperanza Such +13 more
doaj +3 more sources
Advances in Oral and Maxillofacial Surgery, 2023 Objective: The purpose of this study was to ascertain the correlation between COVID-19 infection and jaw osteonecrosis, along with the identification of risk factors that could be associated with the development of the condition. Another aim of our study
Mohd Aswad Khan +8 more
doaj +2 more sources
Dentistry Journal, 2023 Osteonecrosis of the jaw is a condition in which bone cells die due to various causes. It is classified as drug-induced jaw osteonecrosis, osteoradionecrosis, traumatic, non-traumatic, and spontaneous osteonecrosis. Antiresorptive or antiangiogenic drugs
Božana Lončar Brzak +6 more
doaj +5 more sources
Spontaneous bisphosphonate-related osteonecrosis of the left hemi-mandible: Similarities with phossy jaw [PDF]
, 2012 Intravenous bisphosphonates (BP) play a key role in the treatment of bone metastases. As a long-term side effects BP, a form of avascular osteonecrosis of the jaw has been reported.
Giuseppina Campisi +4 more
openalex +4 more sources
Alterations of bone proteins in medication-related osteonecrosis of the jaw. [PDF]
Eur J Oral SciAbstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Schubert A +6 more
europepmc +2 more sources
Medication-Related Osteonecrosis of the Jaw: An Evidence-Based 2025 Position Statement from a Korean Multidisciplinary Task Force. [PDF]
Endocrinol Metab (Seoul)Kim JW +20 more
europepmc +4 more sources
Osteonecrosis of the Jaw [PDF]
Journal of Oncology Practice, 2006 This review looks at osteonecrosis in the stomatognathic system (mainly the jaws). Osteonecrosis of the jaw (ONJ) is a rare but serious clinical condition. It affects patients treated with bisphosphonates, and also with denosumab, mainly in oncological doses. In osteoporosis, it is a problem of relatively small significance. Article presents a thorough
Catherine Van Poznak, Brent B Ward
openaire +3 more sources
Applied Sciences, 2022 Osteonecrosis of the jaw represents interference by external and internal factors in the natural bone remodeling system. Numerous bone remodeling agents (BMAs), such as bisphosphonates, denosumab, and tyrosine kinase inhibitors, can lead to medication ...
Mihai Vlad Golu +6 more
doaj +1 more source
São Paulo Medical Journal, 2020 BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is still the most prevalent type of osteonecrosis with clinical relevance. In Brazil, bisphosphonate use is high but there is a lack of epidemiological studies on BRONJ. OBJECTIVE: To
Aloizio Premoli Maciel +4 more
doaj +1 more source
Clinical Case Reports, 2023 Key Clinical Message Chronic use of bisphosphonates, in combination with immunosuppressive therapy, increases the risk of jaw osteonecrosis. When sepsis occurs in patients receiving bisphosphonate, osteonecrosis of the jaw should be considered a ...
Kazuhiko Iwasaki, Akihito Okazaki
doaj +1 more source