Osteonecrosis of the jaw in the era of targeted therapy and immunotherapy in oncology
Osteonecrosis of the jaw (ONJ) is a well-known pathological condition in oncology derived from the use of bisphosphonates (BPs) and denosumab. Many molecular and immunological targets have been introduced for daily use in cancer treatment in recent years;
Antonio Fabrizio Nifosì +4 more
semanticscholar +1 more source
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin +8 more
wiley +1 more source
Sinusitis and oroantral fistula in patients with bisphosphonate-associated necrosis of the maxilla [PDF]
BACKGROUND: The management of bisphosphonate related necrosis of the jaw has become clinical routine. While approximately two thirds of the lesions are in the mandible, one third is located in the maxilla.
Andres Stricker +6 more
core +1 more source
Engineered surface strategies to manage dental implant‐related infections
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source
Early-Onset Bevacizumab-Associated Knee Osteonecrosis in a Young Adult With Astrocytoma
We describe a rare case of knee osteonecrosis in a 22-year-old man with astrocytoma and neurofibromatosis type 1 after short-term treatment with bevacizumab and corticosteroids. Magnetic resonance imaging (MRI) identified infarctions and osteonecrosis of
Chandra L. Kakarala +5 more
doaj +1 more source
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje +3 more
wiley +1 more source
Osteopathology induced by bisphosphonates and dental implants: clinical observations [PDF]
Objectives: Although there are many reports about risk factors for the development of BP-associated osteonecrosis of the jaws, the role of dental implants as a local risk factor is still discussed, especially in patients with oral BP treatment. Until now,
Grätz, Klaus-Wilhelm +5 more
core
Oral bisphosphonate-associated osteonecrosis of maxillary bone: a review of 18 cases [PDF]
Biphosphonate-associated maxillary bone osteonecrosis (BPMO) is a complication related to nitrogen-containing biphosphonate therapy. This adverse effect occasionally appears in patients who are administered biphosphonates through intravenous infusion for
Escovich, Livia +3 more
core +1 more source
Analgesic effects of platelet‐rich fibrin (PRF): A systematic review
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin +6 more
wiley +1 more source
Impact of acceleration on bone depiction quality by ultrashort echo time magnetic resonance bone imaging sequences in medication-related osteonecrosis of the jaw [PDF]
Jonas M. Getzmann +7 more
openalex +1 more source

