Results 131 to 140 of about 23,381 (306)
The Use of Imaging Methods in the Diagnosis of Bisphosphonate-related Osteonecrosis of the Jaw
Česká Stomatologie a Praktické Zubní Lékařství, 2012 Objectives: Osteonecrosis of the jaws is a rare side effect of bisphosphonate therapy, occurring especially in oncological patients but also in patients with metabolic bone diseases.
L. Hauer +4 more
doaj +1 more source
Machine learning methods for predicting adverse drug events: A systematic review
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 422-444, February 2026.Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo +8 more
wiley +1 more source
Development of Bone Targeting Drugs. [PDF]
, 2017 The skeletal system, comprising bones, ligaments, cartilage and their connective tissues, is critical for the structure and support of the body. Diseases that affect the skeletal system can be difficult to treat, mainly because of the avascular cartilage
Alméciga-Díaz, Carlos J. +6 more
core +2 more sources
Fanconi Syndrome After a Single Exposure to Intravenous Zoledronic Acid
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Bisphosphonates are commonly used to reduce fracture risk in patients with osteoporosis, in those with malignant metastatic bone disease and for treatment of malignant hypercalcaemia. We present the case of a woman in her 80s admitted with recurrent falls who developed Fanconi syndrome after a single dose of intravenous Zoledronic acid despite
Rita Deb +2 more
wiley +1 more source
Osteonekroza čeljusti udružena s bisfosfonatima – tri prikaza slučaja i pregled literature [PDF]
, 2011 A severe complication of the administration of bisphosphonate-containing medications is known as bisphosphonate-associated osteonecrosis of the jaws (BONJ). A case series of three patients affected by BONJ is presented. These patients currently represent
Anastasia Zheleva +8 more
core +1 more source
Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen +5 more
wiley +1 more source
The Journal of Periodontology, 2019 BACKGROUND The onset mechanism for bisphosphonate-related osteonecrosis of the jaw (BRONJ) has been reported, with a focus on bone remodeling, biofilm formation, and epithelial cell proliferation and migration.
N. Taniguchi +6 more
semanticscholar +1 more source
Dental implants in patients treated with oral bisphosphonates. A bibliographic review [PDF]
, 2009 Bisphosphonates inhibit bone resorption and are used to treat a range of pathologies, including Paget disease, osteoporosis, multiple myeloma and metastases associated with breast or prostate cancer.
Calvo Guirado, José Luis +5 more
core +1 more source
Cancer Science, Volume 117, Issue 2, Page 501-510, February 2026.The KYUCOG‐1901 prospective multicenter study evaluated radium‐223 in 93 Japanese patients with bone‐metastatic castration‐resistant prostate cancer. Ra‐223 was well tolerated, produced meaningful declines in ALP, and yielded a median overall survival of 23.0 months. Early initiation in patients with lower disease burden and integration with subsequent
Masaki Shiota +12 more
wiley +1 more source
Bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma [PDF]
, 2008 Purpose: To review the main clinical-radiographic, therapeutic, and preventive aspects of osteonecrosis related to intravenous bisphosphonate therapy in patients with multiple myeloma.
Cabezas Macián, Antonio +4 more
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