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Is the application of platelet concentrates effective in the prevention and treatment of medication-related osteonecrosis of the jaw? A systematic review.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2020
The aim of this systematic review was to answer the question: Is the application of autologous platelet concentrates (APCs) effective in the prevention and treatment of medication-related osteonecrosis of the jaw (MRONJ)?
L. Fortunato   +3 more
semanticscholar   +1 more source

Pentoxifylline and tocopherol protocol to treat medication-related osteonecrosis of the jaw: A systematic literature review.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2020
PURPOSE Medication-related osteonecrosis of the jaw (MRONJ) is a previously described debilitating condition in which patients experience progressive bone destruction in the maxilla and/or mandible after exposure to certain drugs.
R. Cavalcante, Guilherme Tomasetti
semanticscholar   +1 more source

Treatment of Osteonecrosis of the Jaw

Journal of Craniofacial Surgery, 2015
The definition of bisphosphonate-related osteonecrosis of the jaw (BRONJ) was recently broadened and it is now known as medication-related osteonecrosis of the jaw (MRONJ). To date, the management of MRONJ is controversial. Conservative treatment is recommended, but it is difficult to successfully treat stage 3 MRONJ. Administration of teriparatide for
Eiki, Yamachika   +5 more
openaire   +2 more sources

Antiresorptives and Osteonecrosis of the Jaw

Journal of Evidence Based Dental Practice, 2012
Osteonecrosis of the jaw (ONJ) is an uncommon condition noted to occur in patients who are receiving osteoclast-targeted antiresorptive therapy. The incidence of ONJ in patients taking oral antiresorptives for the management of osteoporosis is low (approximately 1:100,000), whereas it is higher (∼10%) in patients taking intravenous bisphosphonates for ...
Junro, Yamashita, Laurie K, McCauley
openaire   +2 more sources

A novel intraoperative infection detecting liquid for medication-related osteonecrosis of the jaw.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication by antiresorptive medications and the treatment of MRONJ remains unclear. The present study developed a novel intraoperative infection-detecting liquid for MRONJ using various ...
Masahiro Kubo   +8 more
semanticscholar   +1 more source

Conservative Management of Severe Medication-Related Osteonecrosis of the Jaw With Pathological Fracture

The Journal of craniofacial surgery (Print), 2021
Medication-related osteonecrosis of the jaw (MRONJ) is a well-known risk following dental extraction in patients taking certain medications. Pathological fracture secondary to MRONJ often requires complex operative intervention.
Alistair Varidel, Eva Wong
semanticscholar   +1 more source

The efficacy of different local flaps for wound closure of defects after removal of necrotic bone in advanced medication-related osteonecrosis of the jaw: A single-center cohort study.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
For this study, the surgical outcomes of patients with advanced medication-related osteonecrosis of the jaw (MRONJ), treated with different local flaps for soft-tissue closure, were evaluated.
Y. Myoken   +5 more
semanticscholar   +1 more source

Examination of certain single-nucleotide polymorphisms of interleukins 1A and 1B in medication-related osteonecrosis of the jaw - An ambirectional cohort study.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
AIM The aim of this study was to examine particular single-nucleotide polymorphisms (IL-1A-889 C/T - rs1800587, IL-1B +3953 C/T - rs 1143634) of interleukins 1A and 1B in the development and prognosis of medication-related osteonecrosis of the jaw ...
Szófia Szentpéteri   +6 more
semanticscholar   +1 more source

Is the conservative non-surgical management of medication-related osteonecrosis of the jaw an appropriate treatment option for early stages? A long-term single-center cohort study.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2019
PURPOSE No consensus has been reached regarding the best treatment option for early-stage lesions in medication-related osteonecrosis of the jaw (MRONJ). The purpose of the present study was to evaluate the long-time outcomes of conservative non-surgical
O. Ristow   +8 more
semanticscholar   +1 more source

Bisphosphonates and Osteonecrosis of the Jaw

Journal of the American Geriatrics Society, 2011
Bisphosphonates are used worldwide as a successful treatment for people with osteoporosis, which is the major underlying cause of fractures in postmenopausal women and older adults. These agents are successful at increasing bone mass and bone trabecular thickness, decreasing the risk of fracture, and decreasing bone pain, enabling ...
Jodi, Shannon   +3 more
openaire   +2 more sources

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