Results 81 to 90 of about 23,381 (306)

Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone‐Related Diseases

Cell Proliferation, EarlyView.
Engineered BMSCs and vesicles enhance therapy effects for bone diseases via multi‐strategic approaches. ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems.
Xuemei Long, Dan Tan, Qianke Tao, Qiaonan Ye, Luwen Ye, Qing Li, Jingang Xiao   +6 more
wiley   +1 more source

The use of platelet-rich fibrin in the surgical treatment of medication-related osteonecrosis of the jaw: 40 patients prospective study.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2020
OBJECTIVES Medication-related osteonecrosis of the jaw (MRONJ) is defined as exposed bone in the maxillofacial region persisting for more than eight weeks in patients who are or were treated with antiresorptive or antiangiogenic agents and had no ...
J. Zelinka, J. Blahák, V. Peřina, R. Pacasová, J. Treglerová, O. Bulík   +5 more
semanticscholar   +1 more source

Concept, diagnosis and classification of bisphosphonate-associated osteonecrosis of the jaws: a review of the literature [PDF]

, 2016
Background: Bisphosphonates (BPs) and other antiresorptive agents such as denosumab are widely prescribed for the treatment of osteoporosis and are also used in patients with multiple myeloma and metastatic breast or prostate cancer for avoiding bone ...
Bagán Sebastián, José Vicente, Gavaldá Esteve, Carmen   +1 more
core   +1 more source

Prevention Of Drug-Induced Osteonecrosis Of The Jaw In Cancer Patients

Креативная хирургия и онкология, 2022
The occurrence of drug-induced osteonecrosis of the jaw in cancer patients treated using bone-modifying medications (bisphosphonates and denosumab) is a highly relevant research problem studied by dentists, maxillofacial surgeons, and oncologists ...
E. M. Spevak, D. Yu. Christophorando, V. A. Shutov, A. V. Ermakova   +3 more
doaj   +1 more source

Surgical therapy for medication-related osteonecrosis of the jaw in osteoporotic patients treated with antiresorptive agents.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2020
BACKGROUND Medication - related osteonecrosis of the jaw (MRONJ) is a rare but serious complication of antiresorptive and/or antiangiogenic therapy. It mainly affects oncological patients, however, it can occur in patients with metabolic bone diseases ...
L. Hauer, J. Jambura, D. Hrusak, M. Chalupova, P. Pošta, S. Rusnak, V. Vyskočil   +6 more
semanticscholar   +1 more source

Updates on osteonecrosis of the jaw [PDF]

Current Opinion in Supportive & Palliative Care, 2010
Osteonecrosis of the jaw (ONJ) is an uncommon condition noted to occur in patients with cancer who are receiving intravenous bisphosphonates. The cause of ONJ remains unknown. The leading hypotheses addressing the mechanism of ONJ are reviewed here.The present clinical data suggest that ONJ may occur in approximately 5% of patients with metastatic bone
Junro, Yamashita, Laurie K, McCauley, Catherine, Van Poznak   +2 more
openaire   +2 more sources

Adalimumab: Another Medication Related to Osteonecrosis of the Jaws?

Case Reports in Dentistry, 2016
Objective. The acronym MRONJ has been created in order to identify “Medication-Related Osteonecrosis of the Jaw,” observed after the use of Bisphosphonates, RANK ligand inhibitor, and antiangiogenic medications. Only a case of osteonecrosis of the jaw in
Andrea Cassoni, Umberto Romeo, Valentina Terenzi, Marco Della Monaca, Oriana Rajabtork Zadeh, Ingrid Raponi, Maria Teresa Fadda, Antonella Polimeni, Valentino Valentini   +8 more
doaj   +1 more source

Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis

Equine Veterinary Education, EarlyView.
Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch, C. Frank, J. B. Daniels, E. Acutt, E. Contino   +4 more
wiley   +1 more source

Regenerative effect of recombinant human bone morphogenetic protein-2/absorbable collagen sponge (rhBMP-2/ACS) after sequestrectomy of medication-related osteonecrosis of the jaw (MRONJ)

Journal of the Korean Association of Oral and Maxillofacial Surgeons, 2020
Objectives Beyond the original application approved by the U.S. Food and Drug Administration, recombinant human bone morphogenetic protein-2 (rhBMP-2) is used for medication-related osteonecrosis of the jaw (MRONJ) treatment because of its bone ...
Song-Hee Min, No-Eul Kang, S. Song, Jeong-Keun Lee   +3 more
semanticscholar   +1 more source

Ovariectomy Stimulates and Bisphosphonates Inhibit Intracortical Remodeling in the Mouse Mandible [PDF]

, 2010
Objective –  The pathophysiology of osteonecrosis of the jaw (ONJ) is thought to be linked to suppression of intracortical remodeling. The aim of this study was to determine whether mice, which normally do not undergo appreciable amounts of intracortical
Allen, Matthew R., Burr, David B., Kubek, Daniel J   +2 more
core   +1 more source