Results 41 to 50 of about 99,821 (371)

Npp1 promotes atherosclerosis in ApoE knockout mice. [PDF]

, 2011
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition.
Nitschke, Yvonne, Rutsch, Frank, Terkeltaub, Robert, Weissen-Plenz, Gabriele   +3 more
core   +1 more source

Research Models for Studying Vascular Calcification [PDF]

, 2020
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen, Giet, Markus van der, Herrmann, Jaqueline, Schuchardt, Mirjam, Tölle, Markus   +4 more
core   +1 more source

Expression and function of osteopontin in vascular adventitial fibroblasts and pathological vascular remodeling. [PDF]

PLoS ONE, 2011
Osteopontin is known to play important roles in various diseases including vascular disorders. However, little is known about its expression and function in vascular adventitial fibroblasts.
Xin Jin, Guo-xiang Fu, Xiao-dong Li, Ding-liang Zhu, Ping-jin Gao   +4 more
doaj   +1 more source

Strong Associations between Plasma Osteopontin and Several Inflammatory Chemokines, Cytokines, and Growth Factors

Biomedicines, 2021
Osteopontin is a member of the proinflammatory cytokine network, a complex system that involves many chemokines, cytokines, and growth factors. The aim of the present study was to study the associations between osteopontin and a large number of ...
Anders Larsson, Johanna Helmersson-Karlqvist, Lars Lind, Johan Ärnlöv, Tobias Rudholm Feldreich   +4 more
doaj   +1 more source

Osteopontin in patients with chronic obstructive pulmonary disease and coronary heart disease

Alʹmanah Kliničeskoj Mediciny, 2023
Background: Osteopontin is a protein expressed by various cell types, such as endothelial and epithelial cells, osteoclasts, hepatocytes, smooth muscle cells, activated macrophages, and T-cells.
Natalia A. Suvorova, Ivan G. Gordeev, Elena E. Luchinkina   +2 more
doaj   +1 more source

Caspase-independent programmed cell death triggers Ca2PO4 deposition in an in vitro model of nephrocalcinosis [PDF]

, 2018
We provide evidence of caspase-independent cell death triggering the calcification process in GDNF-silenced HK-2 ...
Anglani F., Ceol M, Cristofaro R, Del Prete D, Furlan C, Gianesello L, Priante G, Quaggio F, Terrin L   +8 more
core   +1 more source

The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma

OncoTarget, 2021
Background: Cancer-tumor associated macrophage (TAM)-cancer associated fibroblast (CAF) interactions are an important factor in the tumor microenvironment of hepatocellular carcinoma.
K. Tokuda, Y. Morine, Katsuki Miyazaki, S. Yamada, Yu Saito, M. Nishi, T. Tokunaga, T. Ikemoto, S. Imura, M. Shimada   +9 more
semanticscholar   +1 more source

Osteopontin and `Melanoma Inhibitory Activity': Comparison of Two Serological Tumor Markers in Metastatic Uveal Melanoma Patients [PDF]

, 2009
Background: Evaluation of the protein osteopontin (OPN) as a potential new marker in comparison to melanoma inhibitory activity (MIA) for screening and detection of metastatic uveal melanoma. Methods: Plasma levels of 32 patients with uveal melanoma were
Haritoglou, Christos, Haritoglou, Ingrid, Hein, Ruediger, Maier, Tanja, Schaller, Ulrich Christoph, Wolf, Armin   +5 more
core   +1 more source

IER2-induced senescence drives melanoma invasion through osteopontin

Oncogene, 2021
Expression of the immediate-early response gene IER2 has been associated with the progression of several types of cancer, but its functional role is poorly understood.
L. Kyjacová, Rafael Saup, K. Rönsch, S. Wallbaum, Stefanie Dukowic-Schulze, Amelia Foss, Sandra D. Scherer, M. Rothley, A. Neeb, N. Grau, W. Thiele, S. Thaler, Natascha Cremers, C. Sticht, N. Gretz, B. Garvalov, J. Utikal, J. Sleeman   +17 more
semanticscholar   +1 more source

Osteopontin-c isoform levels are associated with SR and hnRNP differential expression in ovarian cancer cell lines

Tumor Biology, 2017
Osteopontin-c splicing isoform activates ovarian cancer progression features. Imbalanced expression of splicing factors from serine/arginine -rich and heterogeneous ribonucleoproteins families has been correlated with the generation of oncogenic splicing
Durval Santos Marques, Jessica Grativol, Rodrigo Alves da Silva Peres, Aline da Rocha Matos, Etel Rodrigues Pereira Gimba   +4 more
doaj   +1 more source