Results 221 to 230 of about 134,783 (292)

FGF-23 facilitates osteosarcoma metastasis by modulating the miR-4463/LOXL2 axis expression via the ERK, p38, and JNK signaling pathway. [PDF]

Int J Med Sci
Hou CH, Lin CY.
europepmc   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

Cell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao, Yuqing Sun, Yutao Huang, Qinghang Meng, Xinhua Lin, Wei Wei, Xiaofang Tang   +6 more
wiley   +1 more source

Spatial resolution of the metastatic osteosarcoma tumor microenvironment using immunolabeling across murine, canine and human lung. [PDF]

J Transl Med
J A B, Pereira JS, Silver KI, L E M, Muhlinen NV, D R R, D O B, E F E, Mazcko C, A K L.   +9 more
europepmc   +1 more source

Atypical Fibroxanthoma/Pleomorphic Dermal Sarcoma With Osseous Metaplasia: A Series of Three Cases

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare mesenchymal tumors typically arising on sun‐damaged skin of the head and neck in elderly patients. PDS is a more aggressive tumor but with similar demographics, cellular morphology, immunohistochemical features, and genetic findings.
Taylor Novice, Yitong Xu, Thomas Brenn, Scott C. Bresler   +3 more
wiley   +1 more source

Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models. [PDF]

Mol Cancer Ther
Wang Y, Zhang Z, Longo C, Zhang W, Wang Q, Najjar A, Tian X, Lazcano Segura RN, Roth ME, Gill J, Harrison DJ, Xu Z, Yi Y, Zhou X, Jusu S, Stearns TM, Neuhauser SB, Bult CJ, Wang J, Lazar AJ, Gorlick R.   +20 more
europepmc   +1 more source

Correction: The nuclear-cytoplasmic trafficking of a chromatin-modifying and remodelling protein (KMT2C), in osteosarcoma

, 2018
Caterina Chiappetta, Chiara Puggioni, Raffaella Carletti, Vincenzo Petrozza, Carlo Della Rocca, Claudio Di Cristofano   +5 more
openalex   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Collateral Impact of Mannose Supplementation on Metastatic Properties in Osteosarcoma Cell Models. [PDF]

Biology (Basel)
Morita A, Hara T.
europepmc   +1 more source

Transcription factor Snai1-1 induces osteosarcoma invasion and metastasis by inhibiting E-cadherin expression

, 2014
Huiguang Yang, Yunqing Zhang, Zhengming Zhou, Xuefeng Jiang, Aidong Shen   +4 more
openalex   +2 more sources

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source