Results 51 to 60 of about 482,563 (236)

Shaping Reforms and Business Models for the OTC Derivatives Market: Quo vadis? ECMI Research Report No. 5, 15 April 2010 [PDF]

, 2010
Now that the worst of the financial storm is over, regulators are setting new strategies to deal with the systemic importance of the €427 trillion ($604 trillion) over-the-counter (OTC) derivatives market.
Valiante, Diego.
core  

The future of centrally cleared OTC derivatives markets

, 2023
This chapter aims to formulate conjectures about the directions in which centrally cleared over-the-counter (OTC) derivatives markets may develop in the future. It begins by examining the potential effects for centrally cleared OTC derivatives markets of
Stegeman, Rezaheditor, Löber, Klaus, de Seriere, Victoreditor, Callens, EvariestRE210001101499648020025387090000-0003-4037-0025341B32CA-F0EE-11E1-A9DE-61C894A0A6B4, Pearson, Patrickeditor, Zebregs, Baseditor   +5 more
core  

Redescription of the cranial morphology of Amphisbaena braestrupi and Amphisbaena laurenti (Squamata: Amphisbaenidae) from the Pleistocene of Brazil using x‐ray computed tomography

The Anatomical Record, EarlyView.
Abstract Amphisbaenians (Squamata: Amphisbaenidae) are fossorial reptiles with highly specialized cranial morphology, yet their fossil record is frequently limited by fragmentary preservation. This study provides a detailed osteological redescription of the skulls of Amphisbaena braestrupi and Amphisbaena laurenti from the Pleistocene of Lagoa Santa ...
Carolina L. Paiva, Henrique C. Costa, Christy A. Hipsley   +2 more
wiley   +1 more source

Essential Oral Single Nutritional Therapy Products for Inherited Metabolic Diseases: Evidence and Consensus Assessment Using a Modified Delphi Method. [PDF]

J Inherit Metab Dis
ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Stolwijk NN, Penninx BMF, Bosch AM, Langeveld M, Salomons GS, Hollak CEM, Essential Nutritional Therapy Products for IMDs Consensus Group.   +6 more
europepmc   +2 more sources

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Patient‐reported outcomes and medication errors during oral antitumour therapy in paediatrics: Results from the youngAMBORA care programme

British Journal of Clinical Pharmacology, EarlyView.
Aim Increasing use of oral antitumour therapeutics (OAT) in paediatrics is associated with numerous advantages, but also with error‐prone aspects. Based on the randomized AMBORA trial including adults treated with various OAT, we developed a tailored pharmacological/pharmaceutical care programme for children and their caregivers during OAT treatment ...
Phyllis Lensker, Lisa Cuba, Frank Dörje, Martin F. Fromm, Markus Metzler   +4 more
wiley   +1 more source

DNA analysis of Ornithine Transcarbamylase (OTC) deficiency in South African patients [PDF]

, 2004
Hyperammonaemia is not an infrequent presentation in the newborn or neonatal period. While the majority are transitory in nature and due to infective processes or liver pathology/immaturity, a significant number are due to defects in enzymes of the urea ...
Swarts, Liezel Catharine
core   +1 more source

Exonic duplication of the OTC gene by a complex rearrangement that likely occurred via a replication-based mechanism: a case report

BMC Medical Genetics, 2018
Background Ornithine transcarbamylase deficiency (OTCD) is an X-linked recessive disorder involving a defect in the urea cycle caused by OTC gene mutations.
Katsuyuki Yokoi, Yoko Nakajima, Hidehito Inagaki, Makiko Tsutsumi, Tetsuya Ito, Hiroki Kurahashi   +5 more
doaj   +1 more source

Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders

EMBO Molecular Medicine, 2020
Urea cycle disorders (UCD) are inherited defects in clearance of waste nitrogen with high morbidity and mortality. Novel and more effective therapies for UCD are needed.
Leandro R Soria, Sonam Gurung, Giulia De Sabbata, Dany P Perocheau, Angela De Angelis, Gemma Bruno, Elena Polishchuk, Debora Paris, Paola Cuomo, Andrea Motta, Michael Orford, Youssef Khalil, Simon Eaton, Philippa B Mills, Simon N Waddington, Carmine Settembre, Andrés F Muro, Julien Baruteau, Nicola Brunetti‐Pierri   +18 more
doaj   +1 more source

MOLECULAR STUDY OF ORNITHINE TRANSCARBAMYLASE: OTC DEFICIENCY AND ANALYSIS OF MITOCHONDRIAL TARGETING OF THE OTC PRECURSOR [PDF]

Pediatric Research, 1987
MOLECULAR STUDY OF ORNITHINE TRANSCARBAMYLASE: OTC DEFICIENCY AND ANALYSIS OF MITOCHONDRIAL TARGETING OF THE OTC ...
openaire   +1 more source