Results 61 to 70 of about 236,560 (230)

The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach [PDF]

open access: yes, 2018
Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow ...
Bou-said, Benyebka   +4 more
core  

Using the stress function in the flow of generalized Newtonian fluids through pipes and slits

open access: yes, 2015
We use a generic and general numerical method to obtain solutions for the flow of generalized Newtonian fluids through circular pipes and plane slits. The method, which is simple and robust can produce highly accurate solutions which virtually match any ...
Sochi, Taha
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Fractional Dynamics: Applications of the Caputo Operator in Solving the Sawada–Kotera and Rosenau–Hyman Equations

open access: yesMathematics
This study investigates the fractional-order Sawada–Kotera and Rosenau–Hyman equations, which significantly model non-linear wave phenomena in various scientific fields.
Khudhayr A. Rashedi   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The Influence of the Protrusion Inclination Angle on the Formability of Hollow Joint in the Tube Hydroforming Process

open access: yesJournal of Machine Engineering
Hollow joints formed through the tube hydroforming process offer superior advantages over traditional forming methods such as casting, welding, sheet metal bending, and cutting.
Nguyen Dac Trung, Vu Duc Quang
doaj   +1 more source

Development of an integrated BEM for hot fluid-structure interaction [PDF]

open access: yes
One of the most difficult problems in engine structural component durability analysis is the determination of the temperatures and fluxes in the structural components directly in contact with the hot gas flow path.
Banerjee, P. K., Dargush, G. F.
core   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong   +7 more
wiley   +1 more source

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